Results 161 to 170 of about 23,621 (212)
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Role of c-Myb in chondrogenesis

Bone, 2015
The Myb locus encodes the c-Myb transcription factor involved in controlling a broad variety of cellular processes. Recently, it has been shown that c-Myb may play a specific role in hard tissue formation; however, all of these results were gathered from an analysis of intramembranous ossification.
Oralová, V   +9 more
openaire   +3 more sources

MicroRNAs regulate osteogenesis and chondrogenesis

Biochemical and Biophysical Research Communications, 2012
MicroRNAs (miRNAs) are a class of small molecules and non-coding single strand RNAs that regulate gene expression at the post-transcriptional level by binding to specific sequences within target genes. miRNAs have been recognized as important regulatory factors in organism development and disease expression.
Shiwu, Dong   +3 more
openaire   +2 more sources

In vitro chondrogenesis and cell viability

Developmental Biology, 1974
Abstract Anterior somites cultured with (NSA) or without (SA) notochord, and posterior somites cultured with (NSP) or without notochord (SP) were compared with respect to changes in their DNA content, their potential to synthesize the active sulfate principle phosphoadenosine phosphosulfate (PAPS), and their ability to accumulate 35 S-sulfate ...
J S, Gordon, J W, Lash
openaire   +2 more sources

Multiple functions of BMPs in chondrogenesis

Journal of Cellular Biochemistry, 2004
AbstractThe ability of bone morphogenetic proteins (BMPs) to promote chondrogenesis has been investigated extensively over the past two decades. Although BMPs promote almost every aspect of chondrogenesis, from commitment to terminal differentiation is well known, the mechanisms of BMP action in discrete aspects of endochondral bone formation have only
Byeong S, Yoon, Karen M, Lyons
openaire   +2 more sources

Non‐conventional chondrosarcomas and chondrogenesis

Histopathology, 1985
Pattern formation in chondroid development is compared with growth models exhibited by mesenchymal and myxoid chondrosarcomas. The results reveal strong similarities between mesenchymal chondrosarcoma and normal chondrogenesis. The fine vascularization of the tumor lobules of myxoid chondrosarcoma is discussed in relation to chondroid differentiation ...
J R, Vilanova   +4 more
openaire   +2 more sources

Hypoxia and HIF‐1α in Chondrogenesis

Annals of the New York Academy of Sciences, 2005
Abstract:  In endochondral bone development chondrocytes undergo proliferation, hypertrophic differentiation, mineralization of the surrounding matrix, death, blood vessel invasion, and finally replacement of cartilage with bone. The chondrocytic growth plate is a unique mesenchymal tissue, as it is avascular but it requires blood vessel invasion in ...
openaire   +3 more sources

Environmental enhancement of in vitro chondrogenesis

Developmental Biology, 1971
Abstract In most in vitro tissue interaction studies, it is assumed that the negative control of the culture system (i.e., the tissue which does not differentiate when isolated) is representative of an in vivo situation, and that the isolated tissue is quite unable to differentiate without the interacting tissue.
M L, Ellison, J W, Lash
openaire   +2 more sources

In vitro chondrogenesis in human chondrodysplasias

American Journal of Medical Genetics, 1993
AbstractBone morphogenesis depends on the sequential expression of multiple genes that first allow formation of mesenchymal anlagen, their replacement by cartilage models, and finally, the synthesis of new bone at growth plates. These processes require orchestration of synthesis of multiple collagens, proteoglycans and glycoproteins, the genes for many
openaire   +2 more sources

Inhibition of limb chondrogenesis by fibronectin

Differentiation, 1984
This study compares the chondrogenic capacity of high density cultures prepared from either the developmentally younger, distal region or more advanced proximal region of stage 23/24 limb mesenchyme in high density cultures. Distal cultures undergo extensive chondrogenesis whether in F12 medium supplemented with 10% fetal calf serum, 5% fetal calf ...
B J, Swalla, M, Solursh
openaire   +2 more sources

Mechanical regulation of secondary chondrogenesis

Biorheology: The Official Journal of the International Society of Biorheology, 2006
This article has been retracted. The original article can be found on: http://dev.biologists.org/cgi/reprint/130/19/4729.
Archer, C W   +3 more
openaire   +2 more sources

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