Results 181 to 190 of about 22,928 (224)
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microRNA in Chondrogenesis, Cartilage and Osteoarthritis
Current Rheumatology Reviews, 2012Osteoarthritis (OA) is a multifactorial disease, typified by the loss of articular cartilage, with a strong genetic component. Current work, even with genome-wide association studies, has failed to identify the genes that describe the full genetic susceptibility to the disease.
Barter, Matt J. +2 more
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Vitamin A inhibits chondrogenesis but not myogenesis
Experimental Cell Research, 1980Abstract Limb bud cells were isolated from HH stage 22–23 chick embryos and were grown as a ‘spot culture’ in in vitro conditions which support their differentiation into chondrocytes and myotubes. By day 4 of culture, numerous chondrocyte nodules developed and were scattered mainly in the very centre of the cell spot.
M, Pacifici +3 more
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Chondrogenesis in the external ear of the rat
Zeitschrift für Anatomie und Entwicklungsgeschichte, 1970The differentiation of cartilage in the external ear of the rat proceeds in four steps. Each of them is characterized by a specific biosynthetic activity of the chondroblast resulting in the appearance of a new structural component of the tissue: collagen fibrils, elastin fibers, cartilage ground substance and intracellular fat droplets.
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Developmental control of chondrogenesis and osteogenesis
The International Journal of Developmental Biology, 2000During vertebrate embryogenesis, bones of the vertebral column, pelvis, and upper and lower limbs, are formed on an initial cartilaginous model. This process, called endochondral ossification, is characterized by a precise series of events such as aggregation and differentiation of mesenchymal cells, and proliferation, hypertrophy and death of ...
CANCEDDA, RANIERI +4 more
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Role of Runx Proteins in Chondrogenesis
Critical Reviews in Eukaryotic Gene Expression, 2005The mammalian RUNX protein family comprises three transcription factorsRUNX1, RUNX2, and RUNX3. RUNX1 is involved in hematopoiesis, RUNX2 has multiple roles in osteogenesis and RUNX3 is associated with neural and gut development. In addition, all RUNX proteins are expressed during chondrogenesis, the process by which cartilage is formed.
Carolina A, Yoshida, Toshihisa, Komori
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In vitro chondrogenesis and cell viability
Developmental Biology, 1974Abstract Anterior somites cultured with (NSA) or without (SA) notochord, and posterior somites cultured with (NSP) or without notochord (SP) were compared with respect to changes in their DNA content, their potential to synthesize the active sulfate principle phosphoadenosine phosphosulfate (PAPS), and their ability to accumulate 35 S-sulfate ...
J S, Gordon, J W, Lash
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Multiple functions of BMPs in chondrogenesis
Journal of Cellular Biochemistry, 2004AbstractThe ability of bone morphogenetic proteins (BMPs) to promote chondrogenesis has been investigated extensively over the past two decades. Although BMPs promote almost every aspect of chondrogenesis, from commitment to terminal differentiation is well known, the mechanisms of BMP action in discrete aspects of endochondral bone formation have only
Byeong S, Yoon, Karen M, Lyons
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Non‐conventional chondrosarcomas and chondrogenesis
Histopathology, 1985Pattern formation in chondroid development is compared with growth models exhibited by mesenchymal and myxoid chondrosarcomas. The results reveal strong similarities between mesenchymal chondrosarcoma and normal chondrogenesis. The fine vascularization of the tumor lobules of myxoid chondrosarcoma is discussed in relation to chondroid differentiation ...
J R, Vilanova +4 more
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Cellular interaction and chondrogenesis in vitro
Developmental Biology, 1970Abstract The elaboration of organized tissue structures by dissociated chondrocytes has been analyzed in vitro. Such tissue reconstruction involves not only synthesis of matrix components, but also the organization of matrix around the cells in lacunae. The expression of this tissue phenotype was favored when an initial inoculum of at least 106 cells
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Effect of Oncogenes on Chondrogenesis
Pathology and Immunopathology Research, 2008D, Boettiger, A S, Menko
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