Results 171 to 180 of about 23,621 (212)
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microRNA in Chondrogenesis, Cartilage and Osteoarthritis
Current Rheumatology Reviews, 2012Osteoarthritis (OA) is a multifactorial disease, typified by the loss of articular cartilage, with a strong genetic component. Current work, even with genome-wide association studies, has failed to identify the genes that describe the full genetic susceptibility to the disease.
Barter, Matt J. +2 more
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Vitamin A inhibits chondrogenesis but not myogenesis
Experimental Cell Research, 1980Abstract Limb bud cells were isolated from HH stage 22–23 chick embryos and were grown as a ‘spot culture’ in in vitro conditions which support their differentiation into chondrocytes and myotubes. By day 4 of culture, numerous chondrocyte nodules developed and were scattered mainly in the very centre of the cell spot.
M, Pacifici +3 more
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Chondrogenesis: Genotypic and phenotypic expression
Journal of Cellular Physiology, 1968It is becoming increasingly evident that the in vitro induction of vertebral chondrogenesis may not be due to the acquisition of a new metabolic pattern, but to the stabilization of one that is already existing. The sclerotome region of embryonic chick somites will undergo chondrogenesis in vitro as a response to various stimuli, the most effective ...
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Developmental control of chondrogenesis and osteogenesis
The International Journal of Developmental Biology, 2000During vertebrate embryogenesis, bones of the vertebral column, pelvis, and upper and lower limbs, are formed on an initial cartilaginous model. This process, called endochondral ossification, is characterized by a precise series of events such as aggregation and differentiation of mesenchymal cells, and proliferation, hypertrophy and death of ...
CANCEDDA, RANIERI +4 more
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Chondrogenesis in the external ear of the rat
Zeitschrift für Anatomie und Entwicklungsgeschichte, 1970The differentiation of cartilage in the external ear of the rat proceeds in four steps. Each of them is characterized by a specific biosynthetic activity of the chondroblast resulting in the appearance of a new structural component of the tissue: collagen fibrils, elastin fibers, cartilage ground substance and intracellular fat droplets.
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Role of Runx Proteins in Chondrogenesis
Critical Reviews in Eukaryotic Gene Expression, 2005The mammalian RUNX protein family comprises three transcription factorsRUNX1, RUNX2, and RUNX3. RUNX1 is involved in hematopoiesis, RUNX2 has multiple roles in osteogenesis and RUNX3 is associated with neural and gut development. In addition, all RUNX proteins are expressed during chondrogenesis, the process by which cartilage is formed.
Carolina A, Yoshida, Toshihisa, Komori
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Effect of Oncogenes on Chondrogenesis
Pathology and Immunopathology Research, 2008D, Boettiger, A S, Menko
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Cellular interaction and chondrogenesis in vitro
Developmental Biology, 1970Abstract The elaboration of organized tissue structures by dissociated chondrocytes has been analyzed in vitro. Such tissue reconstruction involves not only synthesis of matrix components, but also the organization of matrix around the cells in lacunae. The expression of this tissue phenotype was favored when an initial inoculum of at least 106 cells
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Notch signaling in chondrogenesis.
International review of cell and molecular biology, 2009The different stages of cartilage development are well described but no transcription factor capable of specifically inducing differentiation to articular cartilage has been identified and little is known about the molecular mechanisms regulating cartilage development.
Camilla, Karlsson, Anders, Lindahl
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Newer Knowledge of Chondrogenesis
Clinical Orthopaedics and Related Research, 1973openaire +2 more sources