Results 171 to 180 of about 22,928 (224)

Chondrogenesis and Developments in Our Understanding

Current Stem Cell Research & Therapy, 2012
Conditions affecting cartilage through damage or age-related degeneration pose significant challenges to individual patients and their healthcare systems. The disease burden will rise in the future as life expectancy increases. This has resulted in vigorous efforts to develop novel therapies to meet current and future needs.
Mabvuure, Nigel, Hindocha, Sandip, Jordan, Daniel, Khan, Wasim S.   +3 more
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MicroRNAs regulate osteogenesis and chondrogenesis

Biochemical and Biophysical Research Communications, 2012
MicroRNAs (miRNAs) are a class of small molecules and non-coding single strand RNAs that regulate gene expression at the post-transcriptional level by binding to specific sequences within target genes. miRNAs have been recognized as important regulatory factors in organism development and disease expression.
Shiwu, Dong, Bo, Yang, Hongfeng, Guo, Fei, Kang   +3 more
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Studies of chondrogenesis in rotating systems

Journal of Cellular Biochemistry, 1993
AbstractA great deal of energy has been exerted over the years researching methods for regenerating and repairing bone and cartilage. Several techniques, especially bone implants and grafts, show great promise for providing a remedy for many skeletal disorders and chondrodystrophies.
P J, Duke, E L, Daane, D, Montufar-Solis
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Role of c-Myb in chondrogenesis

Bone, 2015
The Myb locus encodes the c-Myb transcription factor involved in controlling a broad variety of cellular processes. Recently, it has been shown that c-Myb may play a specific role in hard tissue formation; however, all of these results were gathered from an analysis of intramembranous ossification.
Oralová, V, Matalová, E, Janečková, E, Drobná Krejčí, E, Knopfová, L, Šnajdr, P, Tucker, A S, Veselá, I, Šmarda, J, Buchtová, M   +9 more
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Inhibition of limb chondrogenesis by fibronectin

Differentiation, 1984
This study compares the chondrogenic capacity of high density cultures prepared from either the developmentally younger, distal region or more advanced proximal region of stage 23/24 limb mesenchyme in high density cultures. Distal cultures undergo extensive chondrogenesis whether in F12 medium supplemented with 10% fetal calf serum, 5% fetal calf ...
B J, Swalla, M, Solursh
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Hypoxia and HIF‐1α in Chondrogenesis

Annals of the New York Academy of Sciences, 2005
Abstract:  In endochondral bone development chondrocytes undergo proliferation, hypertrophic differentiation, mineralization of the surrounding matrix, death, blood vessel invasion, and finally replacement of cartilage with bone. The chondrocytic growth plate is a unique mesenchymal tissue, as it is avascular but it requires blood vessel invasion in ...
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In vitro chondrogenesis in human chondrodysplasias

American Journal of Medical Genetics, 1993
AbstractBone morphogenesis depends on the sequential expression of multiple genes that first allow formation of mesenchymal anlagen, their replacement by cartilage models, and finally, the synthesis of new bone at growth plates. These processes require orchestration of synthesis of multiple collagens, proteoglycans and glycoproteins, the genes for many
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Environmental enhancement of in vitro chondrogenesis

Developmental Biology, 1971
Abstract In most in vitro tissue interaction studies, it is assumed that the negative control of the culture system (i.e., the tissue which does not differentiate when isolated) is representative of an in vivo situation, and that the isolated tissue is quite unable to differentiate without the interacting tissue.
M L, Ellison, J W, Lash
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Mechanical regulation of secondary chondrogenesis

Biorheology: The Official Journal of the International Society of Biorheology, 2006
This article has been retracted. The original article can be found on: http://dev.biologists.org/cgi/reprint/130/19/4729.
Archer, C W, Buxton, P, Hall, B K, Francis-West, P   +3 more
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Chondrogenesis: Genotypic and phenotypic expression

Journal of Cellular Physiology, 1968
It is becoming increasingly evident that the in vitro induction of vertebral chondrogenesis may not be due to the acquisition of a new metabolic pattern, but to the stabilization of one that is already existing. The sclerotome region of embryonic chick somites will undergo chondrogenesis in vitro as a response to various stimuli, the most effective ...
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