Results 51 to 60 of about 435,081 (300)

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

open access: yesAdvanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz   +3 more
wiley   +1 more source

Chondroitin sulfate alleviates osteoporosis caused by calcium deficiency by regulating lipid metabolism

open access: yesNutrition & Metabolism, 2023
The use of non-drug intervention for calcium deficiency has attracted attention in recent years. Although calcium carbonate is the preferred raw material for calcium supplementation, there are few reports on the mechanism of the combined action of ...
Tianshu Liu   +5 more
doaj   +1 more source

Catabolism of chondroitin sulfate

open access: yesCellular and Molecular Biology Letters, 2015
AbstractChondroitin sulfate (CS) is a ubiquitous component of the cell surface and extracellular matrix of animal tissues. CS chains are covalently bound to a core protein to form a proteoglycan, which is involved in various biological events including cell proliferation, migration, and invasion.
openaire   +3 more sources

Anti-tumor Study of Chondroitin Sulfate-Methotrexate Nanogels

open access: yesNanoscale Research Letters, 2017
Self-assembly nanogels (NGs) were formed by bioconjugating methotrexate (MTX) with chondroitin sulfate (CS). MTX-CS NGs can greatly enhance the solubility and improve the delivery efficacy of MTX due to the CD44 binding property of CS.
Jinyuan Wang   +4 more
semanticscholar   +1 more source

Engineering Highly Cellularized Living Materials via Mechanical Agitation

open access: yesAdvanced Functional Materials, EarlyView.
A mechanical agitation strategy is developed to engineer highly cellularized living materials, achieving cell densities of up to 1 billion cells per milliliter. By precisely tuning properties such as stiffness and toughness in blood clots, the approach is validated in both in vitro and in vivo studies.
Aram Bahmani   +9 more
wiley   +1 more source

RATIONAL THERAPY OF OSTEOARTHRITIS IN OUTPATIENT CONDITIONS

open access: yesKlinicist, 2014
Aim. To evaluate in the comparative aspect of the symptomatic effectiveness of therapy chondroitin sulfate and it’s combination with glucosamine hydrochloride in patients with osteoarthritis in outpatient conditions and determine the most rational scheme
E. E. Savelova, O. Yu. Maiko
doaj   +3 more sources

Inflammatory microRNA-194 and -515 attenuate the biosynthesis of chondroitin sulfate during human intervertebral disc degeneration

open access: yesOncoTarget, 2017
Intervertebral disc degeneration (IDD) is characterized by dehydration and loss of extracellular matrixes in the nucleus pulposus region. Chondroitin sulfate has been found to be the water-binding molecule that played a key role in IDD.
Bo Hu   +9 more
semanticscholar   +1 more source

A Novel Sprayable Fibrinogen/Glycosaminoglycans/Collagen‐Based Bioink for Skin Wound Healing Applied by a Handheld Dual‐Head Airbrush

open access: yesAdvanced Healthcare Materials, EarlyView.
A dual‐head airbrush‐based spraying device, combined with a fibrinogen bioink enriched with glycosaminoglycans and collagen, enables the delivery of biomaterials and cells to promote wound healing. This system demonstrates effective skin regeneration in vitro and in vivo, with comparable results to autografts.
Paula Pleguezuelos‐Beltrán   +7 more
wiley   +1 more source

Pathobiochemical pathways of redox imbalance in the neurological long-term effects of COVID-19 and the role of chondroitin sulfate in the redox status restoration

open access: yesНеврология, нейропсихиатрия, психосоматика, 2021
The review examines the epidemiology and clinical manifestations of COVID-19 long-term neurological effects, main pathobiochemical mechanisms, and integrated circuits of redox status impairment in COVID-19, such as the decrease of adenosine triphosphate ...
I. V. Sarvilina   +2 more
doaj   +1 more source

Systematic Analysis of Pharmaceutical Preparations of Chondroitin Sulfate Combined with Glucosamine

open access: yesPharmaceuticals, 2017
Glycosaminoglycans are carbohydrate-based compounds widely employed as nutraceuticals or prescribed drugs. Oral formulations of chondroitin sulfate combined with glucosamine sulfate have been increasingly used to treat the symptoms of osteoarthritis and ...
G. R. Santos   +6 more
semanticscholar   +1 more source

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