Efficacy and safety of prednisolone and chloroquine Add on therapy in osteoarthritis of the knee treated with fixed Dose combination of Glucosamine and chondroitin sulfate [PDF]
Background & ObjectiveOsteoarthritis is the most common type of joint disorder and also the main reason to consult Rheumatologists. Furthermore, a high level of weakness especially among elderly is due to OA.
بهلولی, شهاب+2 more
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Cloned mouse cells with natural killer function and cloned suppressor T cells express ultrastructural and biochemical features not shared by cloned inducer T cells. [PDF]
We have examined the morphology, cytochemistry, and biochemistry of mouse leukocyte subsets by analyzing cloned leukocyte populations specialized to perform different immunologic functions.
Cantor, H+10 more
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Abstract The skin, as the body's largest organ, plays essential roles in protection, immune regulation, and homeostasis. Skin trauma, especially chronic wounds such as diabetic ulcers, poses significant clinical challenges. Traditional treatments, while often effective, can be costly and pose risks.
Boxiang Yang+12 more
wiley +1 more source
Differential expression of ADAMTS -1, -4, -5 and TIMP -3 in rat spinal cord at different stages of acute experimental autoimmune encephalomyelitis [PDF]
Experimental autoimmune encephalomyelitis (EAE) is an animal model of inflammatory demyelination, a pathological event common to multiple sclerosis (MS). During CNS inflammation there are alterations in the extracellular matrix (ECM).
A.K. Cross+52 more
core +1 more source
Nanomaterials for promoting axon regeneration after spinal cord injury: Mechanisms and prospects
The effects of clinical therapies for spinal cord injury (SCI) are greatly limited due to poor axon regeneration. This review systematically discusses the ability of nanomaterials (NMs) to treat SCI and the mechanism underlying their therapeutic effects. The properties of NMs that are conducive to axon regeneration after SCI are outlined.
Jia Liu+9 more
wiley +1 more source
Incorporation of thiolated chondroitin sulphate in gelAGE hydrogels and the production of heterogeneous samples, allows us to provide cells with a dynamic environment, by tuning hydrogel viscoelasticity, rather than elasticity alone, for functional advancing tissue engineering replacements.
Manuela A. Boos+3 more
wiley +1 more source
The role of epidermal growth factor-like module containing mucin-like hormone receptor 2 in human cancers. [PDF]
G-protein coupled receptors (GPCRs) are among the most diverse and ubiquitous proteins in all of biology. The epidermal growth factor-seven span transmembrane (EGF-TM7) subfamily of adhesion GPCRs is a small subset whose members are mainly expressed on ...
Bloch, Orin+8 more
core +2 more sources
To engineer meniscus tissue, a combination of silk fibroin, decellularized meniscus extracellular matrix, and gelatin is 3D bioprinted with infrapatellar fat pad‐derived mesenchymal stem cells. Cell addition is found to affect the enzymatic crosslinking and the mechanical properties of the hydrogels, whose Young's modulus matches with human meniscus ...
Jennifer Fritz+6 more
wiley +1 more source
Modulated glycosylation of proteoglycans during differentiation of human B lymphocytes [PDF]
Proteoglycans are mediators of cellular adhesion and regulate growth factor activities. Proteoglycans of B lymphocytes undergo structural changes during B cell ontogeny which may correspond to the specific requirements of the respective microenvironment ...
Ebeling, Olaf+2 more
core +1 more source
A dECM‐based cryogel scaffold with sustained VEGF release is developed to promote angiogenesis in ischemic tissues. Fabricated from decellularized porcine urinary bladder matrix and heparin, the scaffold supports VEGF binding and prolonged release. The cryogel demonstrates enhanced angiogenic potential in vitro and in a murine hindlimb ischemia model ...
Dayeon Roo+7 more
wiley +1 more source