Results 61 to 70 of about 435,081 (300)

An Organ‐on‐Chip Platform for Strain‐Controlled, Tissue‐Specific Compression of Cartilage and Mineralized Osteochondral Interface to Study Mechanical Overloading in Osteoarthritis

Advanced Healthcare Materials, EarlyView.
A mechanically active OsteoChondral Unit (OCU)‐on‐Chip platform mimicking the OCU's functional anatomy and the strain gradient across the osteochondral interface is presented. Upon compartment‐specific hyperphysiological compression, the model replicates mechanisms observed in osteoarthritis (OA) progression, such as calcium crystal accumulation ...
Andrea Mainardi, Anastasiya Börsch, Paola Occhetta, Robert Ivanek, Martin Ehrbar, Lisa Krattiger, Philipp Oertle, Marko Loparic, Ivan Martin, Marco Rasponi, Andrea Barbero   +10 more
wiley   +1 more source

In Vivo Anti-Cancer Mechanism of Low-Molecular-Weight Fucosylated Chondroitin Sulfate (LFCS) from Sea Cucumber Cucumaria frondosa

Molecules, 2016
The low-molecular-weight fucosylated chondroitin sulfate (LFCS) was prepared from native fucosylated chondroitin sulfate (FCS), which was extracted and isolated from sea cucumber Cucumaria frondosa, and the anti-cancer mechanism of LFCS on mouse Lewis ...
Xiaoxiao Liu, Yong Liu, Jiejie Hao, Xiaoliang Zhao, Yinzhi Lang, Fei Fan, C. Cai, Guoyun Li, Lijuan Zhang, Guangli Yu   +9 more
semanticscholar   +1 more source

Mechanical Reinforced and Self‐healing Hydrogels: Bioprinted Biomimetic Methacrylated Collagen Peptide‐Xanthan Gum Constructs for Ligament Regeneration

Advanced Healthcare Materials, EarlyView.
Readily UV‐curing and self‐healing methacrylated collagen peptide (COPMA) hydrogels are developed with tunable mechanical properties. As the interpenetrating network between COPMA and xanthan gum (XG), COPMA‐XG bioinks show improved mechanical properties, printability, and stability, compared to COPMA or XG.
Hongjuan Weng, Monize Caiado Decarli, Lei He, Wen Chen, Sabine van Rijt, Katrien V. Bernaerts, Lorenzo Moroni   +6 more
wiley   +1 more source

Structure and biological activity of a fucosylated chondroitin sulfate from the sea cucumber Cucumaria japonica.

Glycobiology, 2016
A fucosylated chondroitin sulfate (FCS) was isolated from the body wall of Pacific sea cucumber Cucumaria japonicaby extraction in the presence of papain followed by Cetavlon precipitation and anion-exchange chromatography.
N. Ustyuzhanina, M. Bilan, A. Dmitrenok, A. Shashkov, M. Kusaykin, V. Stonik, N. Nifantiev, A. Usov   +7 more
semanticscholar   +1 more source

From Mechanoelectric Conversion to Tissue Regeneration: Translational Progress in Piezoelectric Materials

Advanced Materials, EarlyView.
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang, Sílvio Terra Stefanello, Victor Shahin, Yun Qian   +3 more
wiley   +1 more source

Bioengineered Models of Nerve Regeneration

Advanced Materials Technologies, EarlyView.
Bioengineered nerve regeneration platforms ranging from patterned cell cultures and hydrogels to fibrous scaffolds and microfluidic systems are reviewed, highlighting the complex cellular and biochemical environments essential for nerve repair. Challenges associated with these platforms, such as balancing complexity with throughput and the need for ...
Madalynn Jade Thompson, John Paul Frampton   +1 more
wiley   +1 more source

Isotachophoretic determination of glucosamine and chondroitin sulphate in dietary supplements

Czech Journal of Food Sciences, 2013
Glucosamine and chondroitin sulfate, components of normal cartilage, are used as ingredients in dietary supplements intended to treat osteoarthritis and/or to support joint health.
Eliška VÁCLAVÍKOVÁ, František KVASNIČKA   +1 more
doaj   +1 more source

Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib

Annals of the Rheumatic Diseases, 2015
Objectives To compare the efficacy and safety of chondroitin sulfate plus glucosamine hydrochloride (CS+GH) versus celecoxib in patients with knee osteoarthritis and severe pain.
M. Hochberg, J. Martel-Pelletier, J. Monfort, I. Möller, J. Castillo, N. Arden, F. Berenbaum, F. Blanco, P. Conaghan, G. Doménech, Y. Henrotin, T. Pap, P. Richette, A. Sawitzke, P. du Souich, J. Pelletier   +15 more
semanticscholar   +1 more source

Facile Fabrication of Large‐Area Biofunctionalized Metallic Nanostructures for High Performance Affinity Plasmonic Biosensors

Advanced Materials Technologies, EarlyView.
A novel approach enables facile and reproducible fabrication of gold nanoparticle arrays with tunable near‐infrared plasmonic properties and enhanced sensing accuracy. Using advanced lithography and ion milling, combined with innovative surface chemistry, the approach minimizes ohmic losses and non‐specific sorption, improving biomolecular detection ...
Dario Cattozzo Mor, Adam Benjamin Plšek, Prasanth Asokan, Van‐Truc Vu, Gizem Aktug, Elena Giordani, Elena Ricciardi, Jiri Perutka, Kamil Önder, Ladislav Fekete, Zdeněk Hubička, Chun‐Jen Huang, Jakub Dostalek   +12 more
wiley   +1 more source

INTRACELLULAR SYNTHESIS OF CHONDROITIN SULFATE [PDF]

The Journal of Cell Biology, 1962
In autoradiograms of slices of costal cartilage, incubated for 4 hours in a salt solution containing S35-sulfate and then washed extensively and dehydrated, about 85 per cent of the radioactivity was assignable to the chondrocytes. From alkaline extracts of similarly prepared slices of cartilage, 64 to 83 per cent of the total sulfur-35 in the slices ...
openaire   +3 more sources