Results 41 to 50 of about 15,622 (209)
Heparan sulfate proteoglycan-dependent neutrophil chemotaxis toward PR-39 cathelicidin
Journal of Inflammation, 2006 Cathelicidins are mammalian proteins containing a C-terminal cationic antimicrobial domain. Porcine PR-39 cathelicidin affects leukocyte biology.
Patsch Josef R +6 more
doaj +1 more source
Three-fold mechanism of inhibition of SARS-CoV-2 infection by the interaction of the spike glycoprotein with heparin [PDF]
arXiv, 2021 Heparin has been found to have antiviral activity against SARS-CoV-2. Here, by means of sliding window docking, molecular dynamics simulations and biochemical assays, we investigate the binding mode of heparin to the virus spike glycoprotein and the molecular basis for its antiviral activity.
arxiv
Nature Communications, 2023 Placental malaria is caused by Plasmodium falciparum-infected erythrocytes (IEs) adhering to chondroitin sulfate proteoglycans in placenta via VAR2CSA-type PfEMP1.
Reetesh Raj Akhouri +2 more
doaj +1 more source
Poultry Science, 2023 : This study aimed to assess the influence of glycosaminoglycan (chondroitin and glucosamine sulfates) supplementation in the diet of broilers on the expression of matrix metallopeptidase 9 (MMP-9) and metallopeptidase inhibitor 2 (TIMP-2) genes, the ...
Julyana M.S. Martins +8 more
doaj
Auto-assemblies of Alpha-Cyclodextrin and Grafted Polysaccharides: Crystal Structure and Specific Properties of the Platelets [PDF]
, 2018 Cyclodextrins (CD) are a family of oligosaccharides with a toroid shape, which exhibit a remarkable ability to include guest molecules in their internal cavity providing a hydrophobic environment for poorly soluble molecules. Recently new types of inclusions of alpha CD with alkyl grafted polysaccharide chains (pullulan, chitosan, dextran, amylopectin,
arxiv +1 more source
A Large Chondroitin Sulfate Proteoglycan, Versican, in Porcine Predentin [PDF]
Journal of Oral Biosciences, 2011 Proteoglycans and their constituent glycosaminoglycan (GAG) have been proposed to be involved in the inhibition of mineralization in unmineralized tissue, predentin. Among the proteoglycans secreted by odontoblasts, we focused on the large chondroitin sulfate proteoglycan, versican, for its large binding capacity for calcium ions.
Makoto Fukae +3 more
openaire +3 more sources
Nature Communications, 2016 Chondroitin sulfate proteoglycans (CSPGs) secreted by astrocytes are known to inhibit OPC differentiation and remyelination. Here, the authors identify a novel CSPG synthesis inhibitor and find it can rescue OPC differentiation in vitroand accelerate ...
Michael B. Keough +12 more
doaj +1 more source
Cell Reports, 2016 The basement membrane is crucial for cell polarity, adhesion, and motility, but how it is assembled on the cell surface remains unclear. Here, we find that ablation of glycosaminoglycan (GAG) side chains of proteoglycans in the neuroretina disrupts the ...
Chenqi Tao, Xin Zhang
doaj +1 more source
Pattern of chondroitin sulfate proteoglycan expression after ablation of the sensorimotor cortex of the neonatal and adult rat brain [PDF]
Archives of Biological Sciences, 2008 The central nervous system has a limited capacity for self-repair after damage. However, the neonatal brain has agreater capacity for recovery than the adult brain.
Dacić Sanja +6 more
doaj +1 more source
Biophysical and biomechanical properties of cartilage [PDF]
arXiv, 2023 Cartilage is a connective tissue that covers the surfaces of bones in joints and provides a smooth gliding surface for movement. It is characterized by specific biophysical properties that allow it to withstand compressive loads, distribute mechanical forces, and maintain tissue integrity.
arxiv