Results 61 to 70 of about 15,622 (209)
Journal of Lipid Research, 1992 Stimulation of rat serosal mast cells in vitro triggers exocytosis of secretory granules from their cytoplasm. Thereupon, the granules lose their perigranular membranes, and about 40% of the heparin proteoglycans and all of the chondroitin sulfate ...
KA Lindstedt, JO Kokkonen, PT Kovanen
doaj
Serglycin: at the crossroad of inflammation and malignancy
Frontiers in Oncology, 2014 Serglycin has been initially characterized as an intracellular proteoglycan expressed by hematopoietic cells. All inflammatory cells highly synthesize serglycin and store it in granules, where it interacts with numerous inflammatory mediators, such as ...
Angeliki eKorpetinou +6 more
doaj +1 more source
Direct quantification of brown algae-derived fucoidans in human plasma by a fluorescent probe assay [PDF]
arXiv, 2016 Fucoidan is a generic term for a class of fucose rich, structurally diverse sulfated polysaccharides that are found in brown algae and other marine organisms. Depending on the species from which the fucoidan is extracted, a wide variety of biological activities including antitumor, antiinflammatory, immune-modulating, antiviral, antibacterial and pro ...
arxiv
End-functionalized glycopolymers as mimetics of chondroitin sulfate proteoglycans
Chemical Science, 2010 Glycosaminoglycans are sulfated polysaccharides that play important roles in fundamental biological processes, such as cell division, viral invasion, cancer and neuroregeneration. The multivalent presentation of multiple glycosaminoglycan chains on proteoglycan scaffolds may profoundly influence their interactions with proteins and subsequent ...
Lee, Song-Gil +6 more
openaire +6 more sources
Inhibition of neurite growth by the NG2 chondroitin sulfate proteoglycan [PDF]
The Journal of Neuroscience, 1994 The chondroitin sulfate proteoglycans (CSPGs) have been implicated as both positive and negative modulators of axonal growth; however, the functional properties of only a few specific CSPGs have been investigated. Here we demonstrate that NG2, an integral membrane CSPG expressed on the surfaces of glial progenitor cells, inhibits neurite growth from ...
Chang-Lin Dou, Joel M. Levine
openaire +2 more sources
Ligand-induced Coupling versus Receptor Pre-association: Cellular automaton simulations of FGF-2 binding [PDF]
J. Theor. Biol. 227(2) 239-251 (2004), 2003 The binding of basic fibroblast growth factor (FGF-2) to its cell surface receptor (CSR) and subsequent signal transduction is known to be enhanced by Heparan Sulfate Proteoglycans (HSPGs). HSPGs bind FGF-2 with low affinity and likely impact CSR-mediated signaling via stabilization of FGF-2-CSR complexes via association with both the ligand and the ...
arxiv
A Mechanistic Model of Annual Sulfate Concentrations in the United States [PDF]
arXiv, 2020 We develop a mechanistic model to analyze the impact of sulfur dioxide emissions from coal-fired power plants on average sulfate concentrations in the central United States. A multivariate Ornstein-Uhlenbeck (OU) process is used to approximate the dynamics of the underlying space-time chemical transport process, and its distributional properties are ...
arxiv
Structure of glassy lithium sulfate films sputtered in nitrogen (LISON): Insight from Raman spectroscopy and ab initio calculations [PDF]
, 2007 Raman spectra of thin solid electrolyte films obtained by sputtering a lithium sulfate target in nitrogen plasma are measured and compared to ab initio electronic structure calculations for clusters composed of 28 atoms. Agreement between measured and calculated spectra is obtained when oxygen atoms are replaced by nitrogen atoms and when the nitrogen ...
arxiv +1 more source
Quantification of sulfated polysaccharides in urine by the Heparin Red mix-and-read fluorescence assay [PDF]
arXiv, 2018 Quantification of sulfated polysaccharides in urine samples is relevant to pharmacokinetic studies in drug development projects and to the non-invasive diagnosis and therapy monitoring of mucopolysaccharidoses. The Heparin Red Kit is a particularly simple and user friendly fluorescence assay for the quantification of sulfated polysaccharides and has ...
arxiv
Biomolecules, 2020 The chondroitin sulfate (CS)-rich dense extracellular matrix surrounding neuron cell bodies and proximal dendrites in a mesh-like structure is called a perineuronal net (PNN).
Satomi Nadanaka +5 more
doaj +1 more source