Results 91 to 100 of about 16,028 (258)

Biochemical characterization and modulation of LH/CG-receptor during human trophoblast differentiation.: LH/CG-R in human trophoblast differentiation. [PDF]

, 2007
Due to the key role of the human chorionic gonadotropin hormone (hCG) in placental development, the aim of this study was to characterize the human trophoblastic luteinizing hormone/chorionic gonadotropin receptor (LH/CG-R) and to investigate its ...
Badet, Josette, Evain-Brion, Danièle, Ferreira, Fatima, Frendo, Jean-Louis, Gerbaud, Pascale, Guibourdenche, Jean, Marpeau, Olivier, Meduri, Geri, Pidoux, Guillaume, Tsatsaris, Vassilis   +9 more
core   +4 more sources

Regulation of the Human Chorionic Gonadotropin α- and β-Subunit Promoters by AP-2 [PDF]

Journal of Biological Chemistry, 1997
Production of the placental hormone, chorionic gonadotropin (CG), increases dramatically as cytotrophoblasts fuse to form syncytiotrophoblasts. The CG alpha- and beta-promoters are both responsive to cAMP, although the kinetics of cAMP stimulation are different.
W, Johnson, C, Albanese, S, Handwerger, T, Williams, R G, Pestell, J L, Jameson   +5 more
openaire   +2 more sources

Role of disulfide bond formation in the folding of human chorionic gonadotropin beta subunit into an alpha beta dimer assembly-competent form.

Journal of Biological Chemistry, 1990
The malignant trophoblastic cell line JAR was used as a model system to study protein folding in intact cells. We have used this model previously to identify conformational intermediates in the production of an assembly-competent form of the human ...
J S Beebe, K. Mountjoy, R. Krzesicki, F. Perini, R. W. Ruddon   +4 more
semanticscholar   +1 more source

Signal Amplification in the HPT Axis—Evidence for Its Existence, Location, Significance, and Molecular Mechanisms

Acta Physiologica, Volume 242, Issue 4, April 2026.
ABSTRACT Thyroid hormones (THs) are under negative feedback regulation via the hypothalamic–pituitary‐thyroid (HPT) axis. How this axis operates to keep the circulating THs within a narrow physiological range is not well understood quantitatively. Led by the design principle of robust homeostatic feedback control, here we review and synthesize the ...
Li Jing, Sarahna A. Moyd, Qiang Zhang
wiley   +1 more source

First Trimester Aneuploidy Screening Program for Preeclampsia Prediction in a Portuguese Obstetric Population

Obstetrics and Gynecology International, 2014
Objective. To evaluate the performance of a first trimester aneuploidy screening program for preeclampsia (PE) prediction in a Portuguese obstetric population, when performed under routine clinical conditions. Materials and Methods.
Cláudia Teixeira, Eduardo Tejera, Helena Martins, António Tomé Pereira, Altamiro Costa-Pereira, Irene Rebelo   +5 more
doaj   +1 more source

Triploidia fetal associada à diminuição da subunidade beta e do estriol não-conjugado no soro materno Fetal triploidy associated with low levels of unconjugated estriol and beta-subunit in maternal serum

Revista Brasileira de Ginecologia e Obstetrícia, 1999
Relatamos um caso de triploidia fetal não-molar detectada na 20ª semana gestacional por cordocentese realizada em razão de estudo ultra-sonográfico que revelou retardo do crescimento intra-uterino e grave oligoidrâmnio.
Eduardo Vieira Neto, Luiz Fernando Zingoni, Armando A. Fonseca   +2 more
doaj   +1 more source

IGF‐1 Deficiency Serves as an Integrated Biomarker Pathogenic Driver and Predictor in Poor Ovarian Response

Advanced Science, Volume 13, Issue 18, 27 March 2026.
IGF‐1 deficiency underlies poor ovarian response (POR), as reduced levels in follicular fluid and granulosa cells impair antral follicle formation and compromise reproductive outcomes. Including IGF‐1 as a biomarker significantly enhances the accuracy of models predicting both PORrisk and pregnancy success.
Zhu Hu, Yuanyuan Yu, Guanyou Huang, Jinnan Li, Chao Yang, Aizhuan Long, Jia Tang, Tengxiang Chen, Shuyun Zhao, Tuo Zhang   +9 more
wiley   +1 more source

Revisiting the expression and function of follicle-stimulation hormone receptor in human umbilical vein endothelial cells [PDF]

, 2016
Expression of follicle-stimulation hormone receptor (FSHR) is confined to gonads and at low levels to some extragonadal tissues like human umbilical vein endothelial cells (HUVEC). FSH-FSHR signaling was shown to promote HUVEC angiogenesis and thereafter
Akerfelt, Malin, Chrusciel, Marcin, Doroszko, Milena, Frentsch, Marco, Huhtaniemi, Ilpo, Kero, Jukka, Li, Xiangdong, Nees, Matthias, Ponikwicka-Tyszko, Donata, Rahman, Nafis A., Stelmaszewska, Joanna, Wolczynski, Slawomir   +11 more
core   +1 more source

Epithelioid Trophoblastic Tumor Similar to Uterine Arteriovenous Malformation: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 3, March 2026.
Overview of the intraoperative and gross pathological findings of an epithelioid trophoblastic tumor mimicking uterine arteriovenous malformation. ABSTRACT Epithelioid trophoblastic tumor (ETT) is a rare subtype of gestational trophoblastic neoplasia, most commonly arising in the cervix or lower uterine segment and often associated with mildly elevated
Huihua Xiang, Xiaoxiao Feng, Shanrong Shu   +2 more
wiley   +1 more source

Midtrimester urine human chorionic gonadotropin beta-subunit core fragment levels and the subsequent development of pre-eclampsia.

American Journal of Obstetrics and Gynecology, 1998
OBJECTIVE Our purpose was to determine whether midtrimester maternal urine human chorionic gonadotropin beta-subunit core fragment predicts later pre-eclampsia.
R. Bahado-Singh, U. Oz, T. Isozaki, E. Seli, E. Kovanci, Chaur-Dong Hsu, L. Cole   +6 more
semanticscholar   +1 more source