Beta-Human Chorionic Gonadotropin Producing Osteosarcoma of the Sacrum in a 26-Year-Old Woman: A Case Report and Review of the Literature [PDF]
, 2015 Ectopic secretion of beta-human chorionic gonadotropin is considered a poor prognostic marker in epithelial tumors. However, very few cases have been reported in sarcomas.
Glass, R. +7 more
core +1 more source
The amino acid sequence of human chorionic gonadotropin. The alpha subunit and beta subunit.
Journal of Biological Chemistry, 1975 The amino acid sequences of both the alpha and beta subunits of human chorionic gonadotropin have been determined. The amino acid sequence of the alpha subunit is: Ala - Asp - Val - Gln - Asp - Cys - Pro - Glu - Cys-10 - Thr - Leu - Gln - Asp - Pro - Phe - Ser - Gln-20 - Pro - Gly - Ala - Pro - Ile - Leu - Gln - Cys - Met - Gly-30 - Cys - Cys - Phe ...
F J, Morgan, S, Birken, R E, Canfield
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Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization
Advanced Science, Volume 13, Issue 26, 8 May 2026.This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin +11 more
wiley +1 more source
Beta-HCG Secretion by a Pulmonary Choriocarcinoma in a Male Patient
Case Reports in Oncological MedicineBackground. Paraneoplastic secretion of beta-subunit of human chorionic gonadotropin (β-HCG) in pulmonary carcinoma is rare. Case Presentation. A 65-year-old man presented with bilateral gynaecomastia with abnormally high levels of β-hCG and elevated ...
Brecht Devos +7 more
doaj +1 more source
The Japanese Journal of Urology, 2005 A 62-year-old man was presented with a firm mass in right scrotum. Serum LDH and AFP were within normal range, but hCG-beta was elevated (2.3 ng/ml). Under the diagnosis of right testicular tumor, he underwent right radical orchiectomy. The specimen was a spermatic cord tumor with poorly differentiated adenocarcinoma.
Yoshida, Soichiro +7 more
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Luteinizing hormone receptor knockout mouse: What has it taught us?
Andrology, Volume 14, Issue 4, Page 1017-1028, May 2026.Abstract Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis ...
Ilpo T. Huhtaniemi
wiley +1 more source
Proline-rich tyrosine kinase 2 mediates gonadotropin-releasing hormone signaling to a specific extracellularly regulated kinase-sensitive transcriptional locus in the luteinizing hormone beta-subunit gene [PDF]
, 2007 G protein-coupled receptor regulation of gene transcription primarily occurs through the phosphorylation of transcription factors by MAPKs. This requires transduction of an activating signal via scaffold proteins that can ultimately determine the outcome
Naor, Zvi +10 more
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Ectopic Pregnancy In Previously Infertile Women Subsequent Pregnancy Outcome After Laparoscopic Management [PDF]
Al Ameen Journal of Medical Sciences, 2009 Ectopic tubal pregnancy (ETP) is a major event in a woman's reproductive life particularly if it happens after treatment of infertility. It complicates infertility treatment and must be recognized early to simplify the treatment strategy, which must ...
Siddhartha Chatterjee +2 more
doaj
Solution structure of the α-subunit of human chorionic gonadotropin [PDF]
, 1999 The three-dimensional solution structure of the α-subunit in the α, β heterodimeric human chorionic gonadotropin (hCG), deglycosylated with endo-β-N-acetylglucosaminidase-B (dg-α hCG), was determined using 2D homonuclear and 2D heteronuclear 1H, 13C NMR ...
Karimi-Nejad, Y. +5 more
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The Association and diagnostic value between Maternal Serum Placental Markers and Placenta Previa
European Journal of Obstetrics & Gynecology and Reproductive Biology: XObjective: This study aims to evaluate the correlation and diagnostic value of maternal serum placental markers: pregnancy-associated plasma protein-A (PAPP-A), free beta human chorionic gonadotropin (free β-hCG), and alpha fetoprotein (AFP) in relation ...
Panpan Ma, Tingting Hu, Yiming Chen
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