Results 71 to 80 of about 4,284 (223)

Phosphatase PPP1CC Regulates the First Lineage Segregation by GAS5 in Mouse Preimplantation Embryos

Cell Proliferation, Volume 59, Issue 6, June 2026.
Subcortical GAS5 directs PPP1CC phosphatase spatiotemporal positioning during mouse morula‐blastocyst transition, controlling YAP dephosphorylation to drive first embryonic lineage specification. ABSTRACT The transcriptional effector of the Hippo signalling pathway, YAP, regulates the first lineage specification in mouse preimplantation embryos ...
Jianwu Wang, Yan Zhang, Laijin Wu, Hongshuang Xie, Guang Yang, Yiwei Zhang, Cheng Huang, Shanyi Chou, Xuehan Li, Zhonghua Liu, Jiaqiang Wang   +10 more
wiley   +1 more source

Human Chorionic Gonadotropin and CA 15-3 Producing Adenocarcinoma

, 1998
Summary50 years old man suffering from primary lung adenocarcinoma presented with high levels of both beta subunit human chorionic gonadotropin (βHCG) and cancer antigen 15-3 (CA 15-3) in the absence of elevated carcinoembrionic antigen (CEA), alfa ...
A. Arpaci, G. Üçkaya, S. Kömiircü, A. Özet   +3 more
core   +1 more source

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, Volume 13, Issue 26, 8 May 2026.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

Solution structure of the α-subunit of human chorionic gonadotropin

, 1999
The three-dimensional solution structure of the α-subunit in the α, β heterodimeric human chorionic gonadotropin (hCG), deglycosylated with endo-β-N-acetylglucosaminidase-B (dg-α hCG), was determined using 2D homonuclear and 2D heteronuclear 1H, 13C NMR ...
Karimi-Nejad, Y., Vliegenthart, J.F.G., Beer, T. de, Kamerling, J.P., Erbel, P.J.A., Boelens, R.   +5 more
core   +1 more source

Luteinizing hormone receptor knockout mouse: What has it taught us?

Andrology, Volume 14, Issue 4, Page 1017-1028, May 2026.
Abstract Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis ...
Ilpo T. Huhtaniemi
wiley   +1 more source

The amino acid sequence of human chorionic gonadotropin. The alpha subunit and beta subunit.

Journal of Biological Chemistry, 1975
The amino acid sequences of both the alpha and beta subunits of human chorionic gonadotropin have been determined. The amino acid sequence of the alpha subunit is: Ala - Asp - Val - Gln - Asp - Cys - Pro - Glu - Cys-10 - Thr - Leu - Gln - Asp - Pro - Phe - Ser - Gln-20 - Pro - Gly - Ala - Pro - Ile - Leu - Gln - Cys - Met - Gly-30 - Cys - Cys - Phe ...
F J, Morgan, S, Birken, R E, Canfield
openaire   +2 more sources

Pharmacogenetics of follicle‐stimulating hormone action in the male

Andrology, Volume 14, Issue 4, Page 1064-1072, May 2026.
Abstract Male factor infertility (MFI) is involved in half of the cases of couple infertility. The follicle‐stimulating hormone (FSH) therapy is considered efficient to improve semen parameters and pregnancy rate in patients with idiopathic MFI, following the lesson learned from hypogonadotropic hypogonadism.
Andrea Graziani, Giuseppe Grande, Raffele Scafa, Riccardo Selice, Andrea Garolla, Maria Santa Rocca, Cinzia Vinanzi, Alberto Ferlin   +7 more
wiley   +1 more source

First Trimester Aneuploidy Screening Program for Preeclampsia Prediction in a Portuguese Obstetric Population

Obstetrics and Gynecology International, 2014
Objective. To evaluate the performance of a first trimester aneuploidy screening program for preeclampsia (PE) prediction in a Portuguese obstetric population, when performed under routine clinical conditions. Materials and Methods.
Cláudia Teixeira, Eduardo Tejera, Helena Martins, António Tomé Pereira, Altamiro Costa-Pereira, Irene Rebelo   +5 more
doaj   +1 more source

Triploidia fetal associada à diminuição da subunidade beta e do estriol não-conjugado no soro materno Fetal triploidy associated with low levels of unconjugated estriol and beta-subunit in maternal serum

Revista Brasileira de Ginecologia e Obstetrícia, 1999
Relatamos um caso de triploidia fetal não-molar detectada na 20ª semana gestacional por cordocentese realizada em razão de estudo ultra-sonográfico que revelou retardo do crescimento intra-uterino e grave oligoidrâmnio.
Eduardo Vieira Neto, Luiz Fernando Zingoni, Armando A. Fonseca   +2 more
doaj   +1 more source

Advances in the Use of Recombinant Gonadotropins for Reproductive Biotechnologies in Ruminants: A Review

Reproduction in Domestic Animals, Volume 61, Issue 5, May 2026.
ABSTRACT Recombinant gonadotropins, particularly recombinant follicle‐stimulating hormone (rFSH) and recombinant equine chorionic gonadotropin (reCG), have emerged as viable alternatives to traditional animal‐derived hormones in reproductive biotechnologies. This review aims to provide an updated and comprehensive overview of recombinant gonadotropins,
Vitória Leite Di Domenico, Fabiane Pereira de Moraes, Natália Ávila de Castro, Fernando Caetano de Oliveira, Diogo Magnabosco, Bernardo Garziera Gasperin   +5 more
wiley   +1 more source