Results 61 to 70 of about 4,284 (223)

The combined screening test in the first trimester of pregnancy and preeclampsia [PDF]

open access: yesScripta Medica, 2015
Introduction: The combined screening test in the first trimester of pregnancy and determination of biochemical markers, pregnancy-associated plasma protein-A (PAPP-A) and free beta subunit of human chorionic gonadotropin (free ß-hCG) were measured to ...
Đorđević Aleksandra   +1 more
doaj  

Semen quality in patients with testicular cancer is associated with age and with greatly elevated levels of beta human chorionic gonadotropin

open access: yesAndrology, EarlyView.
Abstract Background Poor semen quality is a well‐known feature in patients with testicular germ cell tumours (GCTs) at the time of diagnosis but the underlying biological reasons are incompletely understood. Objectives This study aimed to identify GCT‐specific clinical factors that are involved with poor semen quality in GCT patients.
Klaus‐Peter Dieckmann   +9 more
wiley   +1 more source

Decreased levels of genuine large free hCG alpha in men presenting with abnormal semen analysis

open access: yesReproductive Biology and Endocrinology, 2011
Background The pregnancy hormone human chorionic gonadotropin (hCG) and its free subunits (hCG alpha, hCG beta) are produced in the male reproductive tract and found in high concentrations in seminal fluid, in particular hCG alpha.
Plas Eugen   +5 more
doaj   +1 more source

Predicting fetal growth retardation: mathematical modeling

open access: yesАкушерство, гинекология и репродукция, 2023
Introduction. Annually, more than 13 million neonates are born with fetal growth retardation (FGR) worldwide. FGR increases prenatal mortality and morbidity.
E. V. Kudryavtseva   +3 more
doaj   +1 more source

Identification of MEF2A, MEF2C, and MEF2D interactomes in basal and Fsk‐stimulated mouse MA‐10 Leydig cells

open access: yesAndrology, EarlyView.
Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos   +4 more
wiley   +1 more source

Parallel Liquid Biopsy Analysis of miR‐371a‐3p and Cell‐Free DNA in an Unselected Cohort of Patients With Testicular Germ Cell Tumors

open access: yesAndrology, EarlyView.
ABSTRACT Background Despite robust data showing strong potential to improve diagnosis and disease monitoring in testicular germ cell tumors (TGCTs), miR‐371a‐3p testing has not yet been implemented in routine clinical practice. Cell‐free DNA (cfDNA) represents another promising liquid biopsy biomarker that may provide complementary molecular ...
Laura Matouskova   +6 more
wiley   +1 more source

The role of the free beta subunit of human chorionic gonadotropin in human malignancy

open access: yes, 2020
Detection of an elevated level of placental derived β-subunit of human chorionic gonadotropin hormone (hCGβ) in blood or urine is used clinically for the confirmation of pregnancy.
Sinnappan, S, Baxter, R, Marsh, D
core  

Lactate metabolism and lactylation in female reproductive diseases: From metabolic rewiring to biomarkers and translational therapeutics

open access: yesClinical and Translational Medicine, Volume 16, Issue 6, June 2026.
1. Lactate‐derived histone lactylation links glycolytic reprogramming to epigenetic regulation in female reproductive diseases. 2. In endometriosis, lactylation may promote inflammatory remodelling, immune dysregulation and ferroptosis resistance. 3. In PCOS, lactylation connects metabolic disturbance to granulosa‐cell dysfunction and hyperandrogenism.
Jiajun Qiao   +5 more
wiley   +1 more source

Generation of Human chorionic gonadotropin Beta Subunit Specific Monoclonal Antibody Using a Synthetic Peptide

open access: yes, 1999
Human chorionic gonadotropin (hCG) is well known for early immunological and bioassay tests for early detection of pregnancy. Since the hormone specific beta subunit confers unique biological and immunological specificity to hCG, immunochemical ...
Huang, Zhe
core   +1 more source

Multi‐Omics Reveals Early Pregnancy Placental Dysfunction Associated With Preterm and Term Preeclampsia

open access: yesMedComm, Volume 7, Issue 6, June 2026.
Preeclampsia, a severe pregnancy‐induced disorder unique to humans, affects ∼5% of pregnancies globally. To understand the pathogenesis of preeclampsia, this study performed a comprehensive multi‐omics analysis of early pregnancy placental biopsies (chorionic villus samples) from pregnancies that later developed preterm/term preeclampsia, compared to ...
Ellen Menkhorst   +13 more
wiley   +1 more source

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