Results 101 to 110 of about 4,869 (131)
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Human chorionic gonadotropin beta-subunit nicking enzymes in pregnancy and cancer patient serum.
The Journal of Clinical Endocrinology & Metabolism, 1994hCG is a dimer composed of an alpha- and a beta-subunit, joined noncovalently. In addition to the hCG dimer, uncombined alpha- and beta-subunits (free beta) and nicked hCG and free beta molecules (cleaved at 44-45 or 47-48) can be detected in the circulation. Of these circulating molecules, only the intact hCG dimer fully expresses biological activity.
Andrew Kardana, Laurence A. Cole
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American Journal of Obstetrics and Gynecology, 1982
Abstract Luteinizing hormone-human chorionic gonadotropin (LH-hCG), beta subunit of human chorionic gonadotropin (β-hCG), follicle-stimulating hormone (FSH), estradiol, cortisol, and testosterone were determined and correlated with each other in 62 samples of cord serum.
Takao Fukaya+6 more
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Abstract Luteinizing hormone-human chorionic gonadotropin (LH-hCG), beta subunit of human chorionic gonadotropin (β-hCG), follicle-stimulating hormone (FSH), estradiol, cortisol, and testosterone were determined and correlated with each other in 62 samples of cord serum.
Takao Fukaya+6 more
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Life Sciences, 1997
Human chorionic gonadotropin (hCG) and the beta subunit of this dimer glycoprotein hormone (beta hCG) have been reported by us to inhibit HIV replication. In order to identify the active site responsible for the antiviral activity, twelve overlapping peptides spanning across beta hCG were examined for their effect against HIV-caused cell death ...
John E. Powell+2 more
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Human chorionic gonadotropin (hCG) and the beta subunit of this dimer glycoprotein hormone (beta hCG) have been reported by us to inhibit HIV replication. In order to identify the active site responsible for the antiviral activity, twelve overlapping peptides spanning across beta hCG were examined for their effect against HIV-caused cell death ...
John E. Powell+2 more
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ABSENCE OF THE COOH-TERMINAL PEPTIDE ON ECTOPIC HUMAN CHORIONIC GONADOTROPIN B-SUBUNIT (hCGB)
Endocrinology, 1982A comparison of the physical properties and immunoreactivity of ectopic hCG beta from cultured cervical cancer cells and standard hCG beta was performed. The heterogeneity of the preparations was examined by ion-exchange chromatography, and the molecular size by analytical gel filtration. Two distinct forms of ectopic hCG beta were identified. One form
Steven Birken+4 more
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Journal of Bioluminescence and Chemiluminescence, 1992
AbstractAn enhanced chemiluminescence immunoassay for the determination of serum human chorionic gonadotropin (HCG) in specimens from oncology patients has been assessed with respect to its cross‐reactivity with the free HCG ββ‐subunit (HCG‐β). The assay, standardized against the First International Reference Preparation 75/537, had a crossreactivity ...
P. Luppa+4 more
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AbstractAn enhanced chemiluminescence immunoassay for the determination of serum human chorionic gonadotropin (HCG) in specimens from oncology patients has been assessed with respect to its cross‐reactivity with the free HCG ββ‐subunit (HCG‐β). The assay, standardized against the First International Reference Preparation 75/537, had a crossreactivity ...
P. Luppa+4 more
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Evidence for free beta-subunit secretion in so-called human chorionic gonadotropin-positive seminoma
Cancer, 1988In 349 patients with pure seminoma the authors determined human chorionic gonadotropin (HCG) plus the free beta-subunit (HCG-beta) by a polyclonal radioimmunoassay (RIA) and found elevated serum levels in 42 patients (12%). In addition, each HCG and HCG-beta were specifically measured by monoclonal immunoradiometric assays (IRMA) in 19 of these ...
Klaus Mann, Kenneth Siddle
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Immuno-Biological Studies with Beta-Subunit of Human Chorionic Gonadotropin and Its Subfragments
1980The onset of pregnancy is associated with a number of physiological changes brought about by the hormones and other factors synthesized and secreted by the placenta. Human chorionic gonadotropin (hCG) is one of the early products of pregnancy, detectable in circulation between days 8 to 10 post-fertilization (Saxena et al., 1974; Catt et al., 1975 ...
S. Ramakrishnan, G. P. Talwar
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Immunological Specificity of the β Subunit of the Human Chorionic Gonadotropin (HCG)
Hormone and Metabolic Research, 1974G. Rosselin+2 more
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Mass Spectrometric Characterization of the β-Subunit of Human Chorionic Gonadotropin
2003Bowers Ld, Black Rs
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