Results 11 to 20 of about 8,910 (222)
Molecular profile of atypical Leydig cell tumours. [PDF]
HistopathologyCopy number variations by themselves are not sufficient to discriminate between benign and potential malignant Leydig cell tumours (LCTs). Genomic instability was only detected in malignant and atypical cases, and not in any benign tumours. Currently, the presence of metastasis remains the only malignant criterion for LCTs.
Choudhry MFK +6 more
europepmc +2 more sources
Intramural ectopic pregnancy [PDF]
Archive of Oncology, 2010 Gestational trophoblastic neoplasia refers to a subset of gestational trophoblastic conditions characterized with persistently elevated serum β-human chorionic gonadotropin, absence of a normal pregnancy, and a history of normal or abnormal pregnancies ...
Milenković Vera, Lazović Biljana
doaj +1 more source
Variants of human chorionic gonadotropin from pregnant women and tumor patients recognized by monoclonal antibodies [PDF]
, 1993 In biological fluids, hCG and its free alpha- (hCG alpha) and beta-subunits (hCG beta), occur in multiple forms. These various forms differ at the molecular level primarily in glycosylation, but also differ in protein backbone modifications corresponding
Berger, Peter +4 more
core +1 more source
Origin and Occurrence of Human Chorionic Gonadotropin β-Subunit Core Fragment [PDF]
Molecular Endocrinology, 1988 Human chorionic gonadotropin (hCG) beta-subunit core fragment (beta-fragment) is present in the urine of pregnant individuals as well as those with trophoblast disease and certain other cancers at concentrations 0.8 (early pregnancy) to 7 (second trimester pregnancy)-fold greater than that of hCG.
L A, Cole, S, Birken
openaire +2 more sources
Genetic models for the study of luteinizing hormone receptor function [PDF]
, 2015 The luteinizing hormone/chorionic gonadotropin receptor (LHCGR) is essential for fertility in men and women. LHCGR binds luteinizing hormone (LH) as well as the highly homologous chorionic gonadotropin.
Narayan, Prema
core +10 more sources
Negative βhCG and Molar Pregnancy: The Hook Effect
Acta Médica Portuguesa, 2017 Molar pregnancy, included in gestational trophoblastic disease, is a benign pathology with ability to metastasize, usually occurring with excessively high βhCG levels.
Isabel Lobo Antunes +3 more
doaj +1 more source
An unusual cause of gynaecomastia in a male [PDF]
, 2019 Summary: Beta-human chorionic gonadotropin (βhCG) is normally produced by syncytiotrophoblasts of the placenta during pregnancy and aids embryo implantation.
Bano, G +4 more
core +1 more source
Акушерство, гинекология и репродукция, 2022 Aim: to find out the predictive value of blood serum biochemical parameters PAPP-A (pregnancy-associated plasma protein A) and β-hCG (beta subunit of human chorionic gonadotropin) in the assessment of unfavorable pregnancy outcomes in women infected by ...
S. Yu. Pseush +2 more
doaj +1 more source
Prenatal Identification of a Novel <i>ITGB4</i> Gene Mutation Associated With Junctional Epidermolysis Bullosa: A Case Report. [PDF]
Clin Case RepUltrasonographic characteristics of fetal junctional epidermolysis bullosa associated with ITGB4 gene mutation. ABSTRACT Homozygous or compound heterozygous mutations in the ITGB4 gene are associated with the pathogenesis of junctional epidermolysis bullosa, characterized by increased fragility of the skin and mucous membranes.
Xu Q +7 more
europepmc +2 more sources
The Pathogenic TSH β-Subunit Variant C105Vfs114X Causes a Modified Signaling Profile at TSHR [PDF]
, 2019 1) Background: Central congenital hypothyroidism (CCH) is a rare endocrine disorder that can be caused by mutations in the β-subunit of thyrotropin (TSHB).
Biebermann, Heike +6 more
core +1 more source