Results 11 to 20 of about 4,869 (131)

First-trimester or second-trimester screening, or both, for Down's syndrome [PDF]

, 2005
BACKGROUND: It is uncertain how best to screen pregnant women for the presence of fetal Down's syndrome: to perform first-trimester screening, to perform second-trimester screening, or to use strategies incorporating measurements in both trimesters ...
Ball, RH, Berkowitz, RL, Bianchi, DW, Bukowski, R, Canick, JA, Carr, SR, Comstock, CH, Craigo, SD, D'Alton, ME, Dugoff, L, Dukes, K, FASTER Res Consortium, Gross, SJ, Hackshaw, AK, Lambert-Messerlian, G, Malone, FD, Nyberg, DA, Rudnicka, AR, Timor-Tritsch, IE, Wald, NJ, Wolfe, HM   +20 more
core   +1 more source

Ability of human chorionic gonadotropin β-subunit to inhibit the steroidogenic response to lutropin [PDF]

Biochemical Journal, 1979
Ability of the beta-subunit of human chorionic gonadotropin to inhibit the response to lutropin (luteinizing hormone, LH) was tested in the immature rat ovarian system and pregnant-mare-serum-gonadotropin-primed rat ovarian system with progesterone production being used as the response.
Dighe, RR, Muralidhar, K, Moudgal, NR
openaire   +3 more sources

The Pathogenic TSH β-Subunit Variant C105Vfs114X Causes a Modified Signaling Profile at TSHR [PDF]

, 2019
1) Background: Central congenital hypothyroidism (CCH) is a rare endocrine disorder that can be caused by mutations in the β-subunit of thyrotropin (TSHB).
Biebermann, Heike, Grüters-Kieslich, Annette, Kalveram, Laura, Kleinau, Gunnar, Rivero-Müller, Adolfo, Scheerer, Patrick, Szymańska, Kamila   +6 more
core   +1 more source

The development of contraceptive vaccines [PDF]

, 2002
The use of vaccination as a means of controlling fertility was established during the last decade with the publication of a successful Phase II trial demonstrating the efficacy of this approach to family planning.
Delves, PJ
core   +1 more source

Making of a unique birth control vaccine against hCG with additional potential of therapy of advanced stage cancers and prevention of obesity and insulin resistance [PDF]

, 2014
Reviewed is the work which led to the development of a unique vaccine that prevents pregnancy in sexually active women without impairment of ovulation and block of their making normally their sex steroid hormones. Being given that hCG is not expressed by
Atrey, Nishu, Chopra, Prem, Gupta, Jagdish C., Kabeer, Rafi Shiraz, Nand, Kripa, Purswani, Shilpi, Rulli, Susana Beatriz, Singh, Priyanka, Talwar, G. P., Vyas, Hemant   +9 more
core   +2 more sources

Human Chorionic Gonadotropin

Journal of Biological Chemistry, 1973
The linear amino acid sequence of the α subunit of human chorionic gonadotropin (hCG-α) has been derived from a study of the tryptic and cyanogen bromide peptides. The total number of amino acids varies from 89 to 92 because of NH2-terminal heterogeneity probably caused by proteolysis of hCG.
Ronald Bellisario, Om P. Bahl, Robert B. Carlsen   +2 more
openaire   +3 more sources

Hyperprolactinemia induced by hCG leads to metabolic disturbances in female mice [PDF]

, 2016
The metabolic syndrome is a growing epidemic; it increases the risk for diabetes, cardiovascular disease, fatty liver, and several cancers. Several reports have indicated a link between hormonal imbalances and insulin resistance or obesity.
Bonaventura, Maria Marta, Calandra, Ricardo Saul, Huhtaniemi, Ilpo T., Lux, Victoria Adela R., Poutanen, Matti, Ratner, Laura Daniela, Rulli, Susana Beatriz, Stevens, Guillermina   +7 more
core   +1 more source

Human chorionic gonadotropin. VII. Preparation and immunocharacteristics of carboxyl-terminal peptides of the .BETA.-subunit of human chorionic gonadotropin.

Chemical and Pharmaceutical Bulletin, 1982
Various carboxyl-terminal peptides of hCG-β were prepared from the corresponding blocked peptides by TFA treatment followed by hydrogenation. The prepared peptides were tested for inhibitory action on the binding between 125I-hCG and the antiserum against the carboxyl-terminal portion of hCG-β.
Mitsuko Maeda, Tetsu Takagi, Shin Iguchi, Yoshio Okada, Chiye Kawasaki, Osamu Tanizawa, Kenji Yamaji, Nagatoshi Sugita, Koichi Kawasaki   +8 more
openaire   +4 more sources

Origin and Occurrence of Human Chorionic Gonadotropin β-Subunit Core Fragment [PDF]

Molecular Endocrinology, 1988
Human chorionic gonadotropin (hCG) beta-subunit core fragment (beta-fragment) is present in the urine of pregnant individuals as well as those with trophoblast disease and certain other cancers at concentrations 0.8 (early pregnancy) to 7 (second trimester pregnancy)-fold greater than that of hCG.
Laurence A. Cole, Steven Birken
openaire   +2 more sources

The amino acid sequence of human chorionic gonadotropin. The alpha subunit and beta subunit.

Journal of Biological Chemistry, 1975
The amino acid sequences of both the alpha and beta subunits of human chorionic gonadotropin have been determined. The amino acid sequence of the alpha subunit is: Ala - Asp - Val - Gln - Asp - Cys - Pro - Glu - Cys-10 - Thr - Leu - Gln - Asp - Pro - Phe - Ser - Gln-20 - Pro - Gly - Ala - Pro - Ile - Leu - Gln - Cys - Met - Gly-30 - Cys - Cys - Phe ...
S. Birken, F. J. Morgan, Robert E. Canfield   +2 more
openaire   +3 more sources