Results 41 to 50 of about 4,869 (131)

Organization and sequence of the gene encoding the human acrosin-trypsin inhibitor (HUSI-II) [PDF]

open access: yes, 1993
A complete cDNA encoding the acrosin-trypsin inhibitor, HUSI-II, was used as a probe to isolate genomic clones from a human placenta library. Three clones which cover the entire HUSI-II gene were isolated and characterized.
Abelson   +28 more
core   +1 more source

Semen quality in patients with testicular cancer is associated with age and with greatly elevated levels of beta human chorionic gonadotropin

open access: yesAndrology, EarlyView.
Abstract Background Poor semen quality is a well‐known feature in patients with testicular germ cell tumours (GCTs) at the time of diagnosis but the underlying biological reasons are incompletely understood. Objectives This study aimed to identify GCT‐specific clinical factors that are involved with poor semen quality in GCT patients.
Klaus‐Peter Dieckmann   +9 more
wiley   +1 more source

Identification of MEF2A, MEF2C, and MEF2D interactomes in basal and Fsk‐stimulated mouse MA‐10 Leydig cells

open access: yesAndrology, EarlyView.
Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos   +4 more
wiley   +1 more source

Urine tests for Down's syndrome screening [PDF]

open access: yes, 2015
Background Down's syndrome occurs when a person has three copies of chromosome 21, or the specific area of chromosome 21 implicated in causing Down's syndrome, rather than two.
Abbas   +524 more
core   +1 more source

Pharmacogenetics of follicle‐stimulating hormone action in the male

open access: yesAndrology, EarlyView.
Abstract Male factor infertility (MFI) is involved in half of the cases of couple infertility. The follicle‐stimulating hormone (FSH) therapy is considered efficient to improve semen parameters and pregnancy rate in patients with idiopathic MFI, following the lesson learned from hypogonadotropic hypogonadism.
Andrea Graziani   +7 more
wiley   +1 more source

Mouse models of altered gonadotrophin action: insight into male reproductive disorders [PDF]

open access: yes, 2014
The advent of technologies to genetically manipulate the mouse genome has revolutionised research approaches, providing a unique platform to study the causality of reproductive disorders in vivo. With the relative ease of generating genetically modified (
Huhtaniemi, Ilpo T.   +4 more
core   +2 more sources

Clustering Longitudinal Data: A Review of Methods and Software Packages

open access: yesInternational Statistical Review, EarlyView.
Summary Clustering of longitudinal data is becoming increasingly popular in many fields such as social sciences, business, environmental science, medicine and healthcare. However, it is often challenging due to the complex nature of the data, such as dependencies between observations collected over time, missingness, sparsity and non‐linearity, making ...
Zihang Lu
wiley   +1 more source

Neuroactive steroid exposure impacts neurodevelopment: Comparison of human and rodent placental contribution

open access: yesJournal of Neuroendocrinology, EarlyView.
Abstract The placenta is a fetal endocrine organ that secretes many neuroactive factors, including steroids, that play critical roles in brain development. The study of the placenta‐brain axis and the links between placental function and brain development represents an emerging research area dubbed “neuroplacentology.” The placenta drives many ...
Claire‐Marie Vacher   +3 more
wiley   +1 more source

Central mechanisms of emesis: A role for GDF15

open access: yesNeurogastroenterology &Motility, Volume 37, Issue 3, March 2025.
Abstract Background Nausea and emesis are ubiquitously reported medical conditions and often present as treatment side effects along with polymorbidities contributing to detrimental life‐threatening outcomes, such as poor nutrition, lower quality of life, and unfavorable patient prognosis.
Tito Borner   +2 more
wiley   +1 more source

The β subunit of human chorionic gonadotropin lacks specificity for malignant cells in serous effusions [PDF]

open access: yesModern Pathology, 2004
The cytologic diagnosis of malignancy is frequently straightforward. For difficult cases, multiple immunostains and immunostain panels have been investigated without consensus. beta-human chorionic gonadotropin (hCG) has been reportedly expressed in malignancies, but not in normal tissue. HCG also has been reported as a specific marker of metastases in
Robert L. Zimmerman, Franz Fogt
openaire   +2 more sources

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