Results 51 to 60 of about 4,869 (131)

Determination of biological activity of gonadotropins hCG and FSH by Forster resonance energy transfer based biosensors [PDF]

open access: yes, 2017
Determination of biological activity of gonadotropin hormones is essential in reproductive medicine and pharmaceutical manufacturing of the hormonal preparations.
Allikalt, Anni   +4 more
core   +1 more source

Mitofusin 1 Drives Preimplantation Development by Enhancing Chromatin Incorporation of Histone H3.3

open access: yesAdvanced Science, Volume 12, Issue 18, May 15, 2025.
MFN1 exerts its function partially through histone H3.3 in early embryos. MFN1 colocalizes with PADI6, and its deficiency results in compromised cytoplasmic lattices and ribosomal subunits, leading to declined H3.3 protein level. This, in turn, hinders the incorporation of H3.3 into the embryonic genome, thereby causing failure of male pronucleus ...
Xiao‐yan Shi   +9 more
wiley   +1 more source

Hydatidiform mole and gestational trophoblastic disease [PDF]

open access: yes, 2009
A mola hidatiforme é uma complicação relativamente infrequente da gravidez, mas com potencial para evolução para formas que necessitam de tratamento sistêmico e podem ser ameaçadoras da vida.
ANDRADE, Jurandyr Moreira de
core   +2 more sources

Detection of the GH analog somatrogon in sports drug testing: Immunological approaches and LC‐HRMS/MS

open access: yesDrug Testing and Analysis, Volume 17, Issue 5, Page 634-646, May 2025.
The detectability of the GH analog somatrogon with approved doping control immunoassays for hGH and hCG was evaluated and a both sensitive and specific qualitative detection assay employing affinity purification, tryptic digestion, and LC‐HRMS/MS was developed to confirm the presence of the drug in suspicious serum samples. Abstract Due to the presumed
Katja Walpurgis   +5 more
wiley   +1 more source

Moderate Day‐To‐Day Variation in First‐Morning Urine Total Luteinizing Hormone Levels Supports the Use of a Single Determination to Identify Imminent Puberty

open access: yesClinical Endocrinology, Volume 102, Issue 5, Page 578-588, May 2025.
ABSTRACT Objectives We aimed to study the daily variation in first‐morning urinary total luteinizing hormone (U‐LH) determination and validate it as a noninvasive method for analyzing age‐ and pubertal stage‐related changes in LH immunoreactivity (LH‐ir) levels to predict imminent onset of central puberty.
And Demir   +3 more
wiley   +1 more source

SDS-PAGE Electrophoretic Property of Human Chorionic Gonadotropin (hCG) and its β-subunit [PDF]

open access: yesInternational Journal of Biological Sciences, 2005
The microheterogeneity property of hCG with regards to its sialic acid contents resulted in variable mobility of the glycoprotein in SDS-PAGE. The intact hCG molecule is composed of two dissimilar subunits, namely alpha- and beta-subunits. The identification of hCG bands in SDS-PAGE was accomplished by the immunoblotting experiment, whereby the ...
Lay-Harn Gam, Aishah Latiff
openaire   +3 more sources

Endometrial carcinoma with ectopic human chorionic gonadotropin expression [PDF]

open access: yes, 2015
• Aggressive course and treatment resistance characterize ectopic human chorionic gonadotropin. • Recurrence of endometrial cancer with ectopic hCG was treated with brachytherapy and EMACO.
Bouzyk, Mark   +4 more
core   +2 more sources

Paternal Obesity‐Induced H3K27me3 Elevation Leads to MANF‐Mediated Transgenerational Metabolic Dysfunction in Female Offspring

open access: yesAdvanced Science, Volume 12, Issue 16, April 24, 2025.
Paternal lifestyle and environmental exposures play a critical role in the offspring's health. The present study established a paternal obesity model and demonstrated that elevated H3K27me3 levels in sperm persist through the 8‐cell embryo stage. This epigenetic modification triggers transgenerational decrease of MANF, inducing ER stress and activating
Yajun Shi   +13 more
wiley   +1 more source

The molecular relationship between antigenic domains and epitopes on hCG [PDF]

open access: yes, 2016
Antigenic domains are defined to contain a limited number of neighboring epitopes recognized by antibodies (Abs) but their molecular relationship remains rather elusive.
Berger, Peter, Lapthorn, Adrian J.
core   +1 more source

Extracellular Vesicles Alter Trophoblast Function in Pregnancies Complicated by COVID‐19

open access: yesJournal of Extracellular Vesicles, Volume 14, Issue 4, April 2025.
ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection and resulting coronavirus disease (COVID‐19) cause placental dysfunction, which increases the risk of adverse pregnancy outcomes. While abnormal placental pathology resulting from COVID‐19 is common, direct infection of the placenta is rare.
Thea N. Golden   +12 more
wiley   +1 more source

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