Results 51 to 60 of about 4,869 (131)
Determination of biological activity of gonadotropins hCG and FSH by Forster resonance energy transfer based biosensors [PDF]
Determination of biological activity of gonadotropin hormones is essential in reproductive medicine and pharmaceutical manufacturing of the hormonal preparations.
Allikalt, Anni+4 more
core +1 more source
Mitofusin 1 Drives Preimplantation Development by Enhancing Chromatin Incorporation of Histone H3.3
MFN1 exerts its function partially through histone H3.3 in early embryos. MFN1 colocalizes with PADI6, and its deficiency results in compromised cytoplasmic lattices and ribosomal subunits, leading to declined H3.3 protein level. This, in turn, hinders the incorporation of H3.3 into the embryonic genome, thereby causing failure of male pronucleus ...
Xiao‐yan Shi+9 more
wiley +1 more source
Hydatidiform mole and gestational trophoblastic disease [PDF]
A mola hidatiforme é uma complicação relativamente infrequente da gravidez, mas com potencial para evolução para formas que necessitam de tratamento sistêmico e podem ser ameaçadoras da vida.
ANDRADE, Jurandyr Moreira de
core +2 more sources
The detectability of the GH analog somatrogon with approved doping control immunoassays for hGH and hCG was evaluated and a both sensitive and specific qualitative detection assay employing affinity purification, tryptic digestion, and LC‐HRMS/MS was developed to confirm the presence of the drug in suspicious serum samples. Abstract Due to the presumed
Katja Walpurgis+5 more
wiley +1 more source
ABSTRACT Objectives We aimed to study the daily variation in first‐morning urinary total luteinizing hormone (U‐LH) determination and validate it as a noninvasive method for analyzing age‐ and pubertal stage‐related changes in LH immunoreactivity (LH‐ir) levels to predict imminent onset of central puberty.
And Demir+3 more
wiley +1 more source
SDS-PAGE Electrophoretic Property of Human Chorionic Gonadotropin (hCG) and its β-subunit [PDF]
The microheterogeneity property of hCG with regards to its sialic acid contents resulted in variable mobility of the glycoprotein in SDS-PAGE. The intact hCG molecule is composed of two dissimilar subunits, namely alpha- and beta-subunits. The identification of hCG bands in SDS-PAGE was accomplished by the immunoblotting experiment, whereby the ...
Lay-Harn Gam, Aishah Latiff
openaire +3 more sources
Endometrial carcinoma with ectopic human chorionic gonadotropin expression [PDF]
• Aggressive course and treatment resistance characterize ectopic human chorionic gonadotropin. • Recurrence of endometrial cancer with ectopic hCG was treated with brachytherapy and EMACO.
Bouzyk, Mark+4 more
core +2 more sources
Paternal lifestyle and environmental exposures play a critical role in the offspring's health. The present study established a paternal obesity model and demonstrated that elevated H3K27me3 levels in sperm persist through the 8‐cell embryo stage. This epigenetic modification triggers transgenerational decrease of MANF, inducing ER stress and activating
Yajun Shi+13 more
wiley +1 more source
The molecular relationship between antigenic domains and epitopes on hCG [PDF]
Antigenic domains are defined to contain a limited number of neighboring epitopes recognized by antibodies (Abs) but their molecular relationship remains rather elusive.
Berger, Peter, Lapthorn, Adrian J.
core +1 more source
Extracellular Vesicles Alter Trophoblast Function in Pregnancies Complicated by COVID‐19
ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection and resulting coronavirus disease (COVID‐19) cause placental dysfunction, which increases the risk of adverse pregnancy outcomes. While abnormal placental pathology resulting from COVID‐19 is common, direct infection of the placenta is rare.
Thea N. Golden+12 more
wiley +1 more source