Assignment of disulfide bonds in the beta subunit of human chorionic gonadotropin.
The assignment of five disulfide bonds in the alpha subunit of human chorionic gonadotropin (hCG) using partial reduction and S-[14C]carboxymethylation has been reported earlier (Mise, T., and Bahl, O. P. (1980) J. Biol. Chem. 255, 8516-8522). Employing a similar approach, we have determined the locations of six disulfide bonds in hCG-beta.
T, Mise, O P, Bahl
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Determination of biological activity of gonadotropins hCG and FSH by Forster resonance energy transfer based biosensors [PDF]
Determination of biological activity of gonadotropin hormones is essential in reproductive medicine and pharmaceutical manufacturing of the hormonal preparations.
Allikalt, Anni +4 more
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Involvement of human chorionic gonadotropin in regulating vasculogenic mimicry and hypoxia-inducible factor-1α expression in ovarian cancer cells [PDF]
BACKGROUND: Human chorionic gonadotropin (hCG) can play a crucial role in angiogenesis. In the present study, we focused on hCG to gain insight into its potential effects on vasculogenic mimicry (VM) in ovarian cancer cells. METHODS: Ovarian cancer OVCAR-
Caoyi Chen +6 more
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Human chorionic gonadotropin (hCG) concentrations during the late first trimester are associated with fetal growth in a fetal sex-specific manner [PDF]
Human chorionic gonadotropin (hCG) is a pregnancy-specific hormone that regulates placental development. hCG concentrations vary widely throughout gestation and differ based on fetal sex.
Barjaktarovic, M. (Mirjana) +6 more
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Chen-Yu Chen,1–3 Yuh-Ming Hwu,2 Chie-Pein Chen,2 Chia-Chen Chang41Department of Medicine, Mackay Medical College, New Taipei City, Taiwan; 2Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei, Taiwan; 3Mackay Junior College of
Chen CY, Hwu YM, Chen CP, Chang CC
doaj
Beta-Subunit of Human Chorionic Gonadotropin in Malignant Lymphoma : An Immunohistochemical Study [PDF]
We present a rare case of a 77-year-old Japanese man with malignant lymphoma associated with production of beta-subunit of human chorionic gonadotropin in the cytoplasms of lymphoma cells in the lymph nodes.
Senba Masachika, Watanabe Masami
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Evolution of placental function in mammals:the molecular basis of gas and nutrient transfer, hormone secretion, and immune responses [PDF]
Placenta has a wide range of functions. Some are supported by novel genes that have evolved following gene duplication events while others require acquisition of gene expression by the trophoblast.
Carter, Anthony Michael
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Study objective To determine the prevalence of false negative point‐of‐care (POC) urine pregnancy tests among emergency department (ED) patients and among those with abdominal pain or vaginal bleeding.
Sarah Kleinschmidt +3 more
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SDS-PAGE Electrophoretic Property of Human Chorionic Gonadotropin (hCG) and its β-subunit [PDF]
The microheterogeneity property of hCG with regards to its sialic acid contents resulted in variable mobility of the glycoprotein in SDS-PAGE. The intact hCG molecule is composed of two dissimilar subunits, namely alpha- and beta-subunits. The identification of hCG bands in SDS-PAGE was accomplished by the immunoblotting experiment, whereby the ...
Lay-Harn, Gam, Aishah, Latiff
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Objective. To evaluate the performance of a first trimester aneuploidy screening program for preeclampsia (PE) prediction in a Portuguese obstetric population, when performed under routine clinical conditions. Materials and Methods.
Cláudia Teixeira +5 more
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