Novas perspectivas no diagnóstico do hipogonadismo pediátrico masculino: a importância do AMH como marcador de células de Sertoli [PDF]
, 2011 Sertoli cells are the most active cell population in the testis during infancy and childhood. In these periods of life, hypogonadism can only be evidenced without stimulation tests, if Sertoli cell function is assessed.
Grinspon, Romina, Rey, Rodolfo Alberto
core +2 more sources
Cancer Medicine, Volume 14, Issue 5, March 2025.ABSTRACT Background Colon cancer and pancreatic ductal adenocarcinoma are among the most aggressive tumors for which therapeutic options are limited. Both cancers share common features, such as some KRAS pathogenic variants and common epidemiology. The integration of multidimensional datasets by combining machine learning and bioinformatics approaches ...
Katia Pane +6 more
wiley +1 more source
Two hormones for one receptor: evolution, biochemistry, actions and pathophysiology of LH and hCG [PDF]
, 2018 Luteinizing hormone (LH) and chorionic gonadotropin (CG) are glycoproteins fundamental for sexual development and reproduction. Since they act on the same receptor (LHCGR), there is a general consensus that LH and hCG are equivalent.
Brigante, Giulia +3 more
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Characterizing the Role of Endocannabinoid Receptor Cnr1 in Mouse Ovarian Granulosa Cells
Cell Biochemistry and Function, Volume 43, Issue 3, March 2025.ABSTRACT The endocannabinoid receptors Cnr1 and Cnr2 have been found in reproductive organs such as the oviduct and uterus. These receptors bind to endocannabinoids, the arachinodoylethanolamine (AEA) and arachinodoylglycerol (2‐AG), respectively. Both cannbinoid receptors have been investigated for their role in implantation and fertilization. However,
Jasmine Randhawa +4 more
wiley +1 more source
Endocrine Journal, 2000 Human chorionic gonadotropin (hCG) is a member of a family of heterodimeric glycoprotein hormones that contain a common alpha-subunit but differ in their hormone-specific beta-subunits. Both subunits have five and six disulfide bonds, respectively, which consist of cystine knot structure.
Madoka Furuhashi, Nobuhiko Suganuma
openaire +4 more sources
Involvement of human chorionic gonadotropin in regulating vasculogenic mimicry and hypoxia-inducible factor-1α expression in ovarian cancer cells [PDF]
, 2016 BACKGROUND: Human chorionic gonadotropin (hCG) can play a crucial role in angiogenesis. In the present study, we focused on hCG to gain insight into its potential effects on vasculogenic mimicry (VM) in ovarian cancer cells. METHODS: Ovarian cancer OVCAR-
Caoyi Chen +6 more
core +1 more source
hCG, the wonder of today's science [PDF]
, 2012 Background hCG is a wonder. Firstly, because hCG is such an extreme molecule. hCG is the most acidic glycoprotein containing the highest proportion of sugars. Secondly, hCG exists in 5 common forms.
Cole, Laurence A
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Human chorionic gonadotropin (hCG) concentrations during the late first trimester are associated with fetal growth in a fetal sex-specific manner [PDF]
, 2017 Human chorionic gonadotropin (hCG) is a pregnancy-specific hormone that regulates placental development. hCG concentrations vary widely throughout gestation and differ based on fetal sex.
Barjaktarovic, M. (Mirjana) +6 more
core +1 more source
Evolution of placental function in mammals:the molecular basis of gas and nutrient transfer, hormone secretion, and immune responses [PDF]
, 2012 Placenta has a wide range of functions. Some are supported by novel genes that have evolved following gene duplication events while others require acquisition of gene expression by the trophoblast.
Carter, Anthony Michael
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Biological functions of hCG and hCG-related molecules [PDF]
, 2010 Background hCG is a term referring to 4 independent molecules, each produced by separate cells and each having completely separate functions. These are hCG produced by villous syncytiotrophoblast cells, hyperglycosylated hCG produced by cytotrophoblast ...
Cole, Laurence A
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