Results 71 to 80 of about 10,464 (192)
The FEBS Journal, EarlyView.Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo +4 more
wiley +1 more source
Generation of iPSC lines from primary human chorionic villi cells
Stem Cell Research, 2015 Primary human chorionic villi (CV) cells were used to generate the iPSC line by retroviral transduction of the four Yamanaka-factors OCT4, SOX2, KLF4 and c-MYC. Pluripotency was confirmed both in vivo and in vitro.
Björn Lichtner +2 more
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Transforming growth factor (TGF)‐β2 and interleukin (IL)‐1β induced morphological and molecular changes consistent with endothelial‐to‐mesenchymal transition (EndMT) in HUVECs isolated from both pregnancies complicated by gestational diabetes (GDM) and non‐GDM pregnancies.
Abigail R. Byford +9 more
wiley +1 more source
Placenta percreta: Histoplathological overview of a rare case
Journal of Dr. NTR University of Health SciencesPlacenta percreta is a rare condition characterized by abnormal proliferation and penetration of the chorionic villi through the full thickness of myometrium and serosa. We present a case of 32-year-old female, G4P2L2A1 with low lying placenta.
Greeshma Sasmal +4 more
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend We investigated how environmental hypoxia and genetic adaptation to high altitudes jointly impact the development of the placental exchange surface in ways that might protect fetal growth potential. We used wild‐derived, lab‐born North American deer mice (Peromyscus maniculatus) from low‐elevation and high‐elevation environments (
Kathryn Wilsterman +6 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Schematic overview of a flow‐driven in vitro model of the human placental barrier designed to study transport processes during pregnancy. The model recreates key features of the maternal–fetal interface, enabling the investigation of how nutrients and therapeutic compounds cross the placental barrier under physiologically ...
Barbara Fuenzalida +7 more
wiley +1 more source
BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 5, Page 888-899, April 2026.ABSTRACT Background Caesarean scar ectopic pregnancy (CSEP) is defined by the implantation and development of a gestational sac inside a caesarean scar defect, but variations in classification systems and diagnostic criteria exist. Objectives This study aimed to systematically review the different criteria used in the medical literature to diagnose ...
Simrit Nijjar +5 more
wiley +1 more source
Immunoexpression of neuropilin-1 in the chorionic villi of HIV-infected preeclamptic South African women of African ancestry. [PDF]
Histochem Cell Biol, 2023 Naidoo N, Abel T, Moodley J, Naicker T.
europepmc +1 more source
Molecular Testing in Sickle Cell Disease: From Newborn Screening to Transfusion Care
International Journal of Laboratory Hematology, Volume 48, Issue 2, Page 295-304, April 2026.ABSTRACT Sickle cell disease (SCD) is one of the most frequent monogenic diseases worldwide and a highly heterogeneous and complex disease. SCD care carries several challenges. This includes early and accurate diagnosis as well as optimal red blood cell transfusion matching in this population carrying a high risk of alloimmunization.
Thomas Pincez, Yves D. Pastore
wiley +1 more source
Prenatal Diagnosis of Renal Anomalies Associated With a Novel Causative Variant in RAP1B Gene
Clinical Case Reports, Volume 14, Issue 3, March 2026.A case of prenatal renal cystic disease and unilateral renal agenesis is reported. Molecular investigations including TRIO next‐generation sequencing analysis using the Clinical exome sequencing protocol identified the c.179G>T, p.(Gly60Val) “de novo” variant in a heterozygous state in the RAP1B gene.
Adalgisa Cordisco +5 more
wiley +1 more source