Results 91 to 100 of about 19,241 (174)

Multi‐Organ Inflammatory and Endocrine Crosstalk Shapes the Early Brain Response to Combined Burn and Blast Injury

The FASEB Journal, Volume 40, Issue 21, 15 November 2026.
Concomitant burn injury and blast‐induced mild TBI lead to a magnified neuroimmune response shaped by endocrine stress‐related pathways and IL‐1R1‐dependent inflammatory signals, which also produce cytokine‐mediated impairment of erythropoiesis. These integrated systemic and CNS responses illustrate how inflammation, hematopoietic adaptation, and early
Hana C. Schwierling, Satarupa Sengupta, John G. Noel, Christopher J. O'Connell, Andrew S. Potter, Mike Adam, Matthew J. Robson, Jason C. Gardner   +7 more
wiley   +1 more source

Estimation of metabolic water production in human and rat brain and spinal cord

Fluids and Barriers of the CNS
Background Cerebrospinal fluid (CSF) is vital to maintain brain homeostasis by facilitating waste removal, nutrient transport, and regulation of intracranial pressure.
Cecilie R. Hvass, Shai D. Ben-Shoshan, Jonathan F. Carlsen, Blanca I. Aldana, Bjørn Quistorff, Adam E. Hansen, Nanna MacAulay   +6 more
doaj   +1 more source

Multimodal Characterization of Glymphatic‐Related Magnetic Resonance Imaging Markers in Huntington's Disease: A Multi‐Cohort Retrospective Study

Annals of Neurology, Volume 100, Issue 5, Page 1055-1067, November 2026.
Objective To characterize magnetic resonance imaging (MRI)‐based glymphatic surrogates in Huntington's disease (HD) using MRI measures of perivascular diffusivity and structural perivascular alterations across multiple large cohorts. Methods We analyzed 2,731 MRI sessions from 880 participants across 3 large retrospective HD cohorts.
Alexia Solomon, Zexi Wang, Francesco Sanvito, Zheng Zhou, Adys Mendizabal, Jingwen Yao   +5 more
wiley   +1 more source

Diagnostic Value of Choroid Plexus-to-Lateral Ventricle Volume Ratio (CLVVR) in First-Trimester Screening (11–13⁺6 Weeks) for Fetal Autosomal Aneuploidies

International Journal of General Medicine
Shanshan Huang,1 Chushuang Zhang,1 Yanqiu Ding,1 Guorong Lv21Department of Ultrasound, Jinjiang Municipal Hospital (Shanghai Sixth People’s Hospital Fujian), Jinjiang, People’s Republic of China; 2Department of Ultrasound Medicine, The Second Affiliated ...
Huang S, Zhang C, Ding Y, Lv G
doaj  

A Multidimensional “Source-Dynamics-Function-Structure” Magnetic Resonance Imaging Framework for Characterizing the Pathophysiological Imaging Profile of Moderate-to-Advanced Parkinson’s Disease Eligible for Deep Brain Stimulation

Brain Science Advances
Objective: To characterize glymphatic- and cerebrospinal fluid (CSF)-related imaging alterations in moderate-to-advanced, deep brain stimulation (DBS)-eligible Parkinson’s disease (PD) using a multidimensional magnetic resonance imaging (MRI) framework ...
Liying Sun, Suhua Miao, Rongsong Zhou, Zhihua Zhang, Tiange Lu, Tiemin Li, Mingyuan Yan, Yu Ma, Yuqi Zhang   +8 more
doaj   +1 more source

Prenatal Diagnosis of Recurrent Fetal Intracranial Hemorrhage and a Maternally Inherited COL4A1 Variant of Uncertain Significance: A Case Report With Maternal Reverse Phenotyping

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT A 33‐year‐old woman with two consecutive pregnancies affected by fetal left periventricular germinal matrix hemorrhage (Grade IV) and progressive ventriculomegaly underwent trio whole‐exome sequencing. A heterozygous COL4A1 c.4249G>C (p.Gly1417Arg) variant, classified as a variant of uncertain significance, was identified in the fetus of the ...
Wei Shi, Hongjing Xu, Caihong Pu, Yuanzhong Liang, Ting Zhao, Xueli Wang, Zhenxing Liu, Chunhua Zhang, Ting Li, Fengquan He   +9 more
wiley   +1 more source

The microbiome and brain metastasis in non‐small cell lung cancer: A graded appraisal and a framework for prevention‐oriented research

Clinical and Translational Medicine, Volume 16, Issue 11, November 2026.
This Review proposes a microbiome–premetastatic brain niche axis connecting gut, lung, and intratumoral microbes with metabolites, blood–brain barrier remodeling, neuroimmune priming, and brain metastasis in NSCLC. It integrates current evidence while distinguishing established mechanisms from associations and hypotheses requiring prospective and ...
Long Liang, Fangjuan Hu, Xiaofeng Wang, Chunhan Tang, Chun Wang, Gefei Jiang, Chungang Zhao, Yin Zhang, Churong Li   +8 more
wiley   +1 more source

Glial Dysfunction and Memory Impairments in a Model of Pediatric Obstructive Sleep Apnea

Glia, Volume 74, Issue 11, November 2026.
Generation and analysis of an snRNA‐seq atlas of the hippocampus in POSA. Validation of reduced protein expression of six genes across four cell types. Cellular‐level investigation of aberrant glial function in POSA using transgenic reporter mice. ABSTRACT Pediatric obstructive sleep apnea (POSA) is a common childhood disease that often causes aberrant
Michael R. Williamson, Jorge Botas, Mahyar J. Hedayatpour, Thea Zlatkov, Akdes Serin Harmanci, Christopher J. Yates, Kenneth Nobleza, Roshan Ailani, Adam C. Adler, Farrah Kheradmand, Hyun Kyoung Lee, Benjamin Deneen, Hyun‐Hwan Jeong, Arvind Chandrakantan   +13 more
wiley   +1 more source

Harmonized Protocol for Segmentation of the Hippocampal Tail on High‐Resolution In Vivo MRI From the Hippocampal Subfields Group (HSG)

Hippocampus, Volume 36, Issue 6, November 2026.
ABSTRACT The hippocampus is a heterogeneous structure with cytoarchitectonically distinct subfields that exhibit heterogeneous lifespan trajectories and are differentially susceptible to diseases. Advances in high‐resolution imaging have accelerated research on these structures, yet variability in segmentation protocols limits cross‐study comparability.
Robin de Flores, Kelsey L. Canada, Thackery Brown, Nicole J. Gervais, Anne Maass, Gustaf Rådman, Jonathan Shine, Hannah L. Tucker, Eóin N. Molloy, Jenna N. Adams, Michelle Baca Reinke, Arnold Bakker, David Berron, Marshall A. Dalton, Kristen M. Kennedy, Renaud LaJoie, Susanne G. Mueller, Noa Ofen, Rosanna K. Olsen, Naftali Raz, Tracy Riggins, Karen M. Rodrigue, Craig Stark, Lei Wang, Laura E. M. Wisse, Paul A. Yushkevich, Valerie A. Carr, Ana M. Daugherty, the Alzheimer's Disease Neuroimaging Initiative, on behalf of the Hippocampal Subfields Group   +29 more
wiley   +1 more source

Associations of ischemic heart disease with brain glymphatic MRI indices and risk of Alzheimer's disease

The Journal of Prevention of Alzheimer's Disease
Background: The impact of ischemic heart disease (IHD) on the brain glymphatic MRI indices and risk of Alzheimer's disease (AD) remains largely unclear.
Ming-Liang Wang, Meng-Meng Yu, Zheng Sun, Jun-Jie Zhang, Jing-Kun Zhang, Xue Wu, Xiao-Er Wei, Yue-Hua Li   +7 more
doaj   +1 more source