Results 101 to 110 of about 19,241 (174)

Pan‐Cancer Landscape of TMEM9 With Experimental Validation in Head and Neck Squamous Cell Carcinoma

The Journal of Gene Medicine, Volume 28, Issue 11, November 2026.
Transmembrane protein 9 (TMEM9) was investigated across cancers using public transcriptomic, clinical, genomic, and immune datasets, followed by functional validation in head and neck squamous cell carcinoma (HNSC). TMEM9 showed cancer‐dependent expression, diagnostic discrimination, prognostic associations, and relationships with immune infiltration ...
Mi Wang, Shangyan Ying, Chunyan Weng, Youfeng Li   +3 more
wiley   +1 more source

Neurodegenerative Diseases: Epidemiology, Risk Factors, Classification, Pathophysiology, Clinical Features, Diagnosis, and Therapeutic Strategies

MedComm, Volume 7, Issue 11, November 2026.
Neurodegenerative diseases share convergent risk architectures and pathological mechanisms, yet diverge in selective vulnerability, clinical presentation, and therapeutic responsiveness. This review integrates cross‐disease epidemiology, pathophysiology, diagnosis, and treatment, highlighting the transition from symptomatic care toward biomarker‐guided
Zimeng He, Jingjing Zeng, Guoqing Wang, Yuxin Li, Feng Zhang   +4 more
wiley   +1 more source

Effects of Pco2 acetazolamide and ouabain on volume and composition of choroid‐plexus fluid. [PDF]

The Journal of Physiology, 1965
A, Ames, K, Higashi, F B, Nesbett
openaire   +2 more sources

Using Manganese‐Enhanced DCE‐MRI to Assess Blood‐Cerebrospinal Fluid Barrier Transport

Magnetic Resonance in Medicine, Volume 96, Issue 5, Page 2083-2091, November 2026.
ABSTRACT PurposeWe developed a dynamic, heavily T2‐weighted (hT2w) FLAIR protocol to resolve acute Mn2+ transport kinetics, as a proxy for Ca2+, across the choroid plexus (ChP)—cerebrospinal fluid (CSF) interface, in vivo. By quantifying intercompartmental Mn2+ dynamics, and comparing these with Gd‐DOTA, we sought to characterize blood‐CSF‐barrier ...
Charith Perera, Zhiping Feng, Shereen Nizari, Phillip Muza, Christina Katsiva, Tammy L. Kalber, Mark F. Lythgoe, Ian F. Harrison, Daniel J. Stuckey, Jack A. Wells   +9 more
wiley   +1 more source

Longitudinal changes of choroid plexus volumes and MRI ratios in multiple sclerosis

Brain Communications
Abstract This longitudinal study aimed to identify the predictive role of choroid plexus enlargement for disability progression and its association with tissue damage in early multiple sclerosis patients. Forty patients with clinically isolated syndrome or early relapsing–remitting multiple sclerosis underwent brain MRI scanning at ...
Britta Krieger, Barbara Bellenberg, Dajana Müller, Hasan Sbaihat, Anna Katharina Roenneke, Theodoros Ladopoulos, Ruth Schneider, Ralf Gold, Carsten Lukas   +8 more
openaire   +1 more source

Human brain matters: Navigating the neuropathology of COVID‐19

Brain Pathology, Volume 36, Issue 6, November 2026.
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland, Angelica Scaramuzza, Marianna Bugiani, Wilma D. J. van de Berg, Jinte Middeldorp   +4 more
wiley   +1 more source

Distinct brain alterations and neurodegenerative processes in cognitive impairment associated with post-acute sequelae of COVID-19

Nature Communications
Although brain alterations have been reported in post-acute sequelae of SARS-CoV-2 (PASC), their prevalence and relationship to neurodegeneration remain unclear.
Dayoung Seo, Yangsean Choi, Eunseon Jeong, Sanghwi Bang, Ji-Sung Lee, In-Hye Jang, Lynkyung Choi, Jin Hee Kim, Wangyoung Shin, Bo-Ra Seo, Shina Kim, Hee-Jae Jung, Ji-Yon Kim, Hyunjin Kim, Young-Min Lim, Ji-Soo Kwon, Euijin Chang, Jacob Lee, Tae-In Kam, Su-Hyung Park, Eun-Jae Lee, Sung-Han Kim   +21 more
doaj   +1 more source

Direct evidence implicating the asymmetrical dimethylarginine (ADMA)‐dimethylarginine dimethylaminohydrolase 1 (DDAH1) pathway in cerebrovascular dysfunction and stroke pathogenesis in mice

British Journal of Pharmacology, Volume 183, Issue 21, Page 6422-6443, November 2026.
Abstract Background and Purpose Asymmetrical dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide synthase (NOS), whereas dimethylaminohydrolase 1 (DDAH1) is primarily responsible for its metabolism. However, the roles of DDAH1 in cerebrovascular regulation are poorly understood. Furthermore, despite evidence that elevated ADMA levels are
Arun Flynn, Alexandra Riddell, Ashton Bernard, Jennifer Haggarty, Stefan Weidt, Jawza Alenazi, Erika Trabold, Delyth Graham, Laura B. Dowsett, James Leiper, Alyson A. Miller   +10 more
wiley   +1 more source

Spotlight commentary: Addressing the persistent problem of benzodiazepine overuse, time for clinical, educational and AI‐driven reform

British Journal of Clinical Pharmacology, Volume 92, Issue 11, Page 3703-3706, November 2026.
Jakša Vukojević, Luka Horvat, Vito Papić, Andrija Štajduhar   +3 more
wiley   +1 more source

Ocular Manifestations of Infectious Salmon Anaemia Virus Infection in Atlantic Salmon (Salmo salar)

Journal of Fish Diseases, Volume 49, Issue 11, November 2026.
ABSTRACT Eyes are essential sensory organs needed by teleost Atlantic salmon for high visual acuity and survival in both the wild and in aquaculture settings. In this work, we assessed the ocular manifestations of Infectious Salmon Anaemia Virus (ISAV) infection in Atlantic salmon by a cohabitation‐mediated infection assay and histological and ...
Emily Mahon, Rebecca R. Kwabiah, Hélène Paradis, Manuel A. Soto‐Dávila, Sathees Duglas, Raja Ram Gurung, Thurka Paramanathan, Ignacio Vasquez, Shams Al‐Badoosh, John Law, Javier Santander, Mark D. Fast, Robert L. Gendron   +12 more
wiley   +1 more source