Results 31 to 40 of about 392,110 (289)
TelNet - a database for human and yeast genes involved in telomere maintenance
BMC Genetics, 2018 Background The ends of linear chromosomes, the telomeres, comprise repetitive DNA sequences in complex with proteins that protects them from being processed by the DNA repair machinery.
Delia M. Braun +4 more
doaj +1 more source
Chromatin status and transcription factor binding to gonadotropin promoters in gonadotrope cell lines. [PDF]
, 2017 BackgroundProper expression of key reproductive hormones from gonadotrope cells of the pituitary is required for pubertal onset and reproduction. To further our understanding of the molecular events taking place during embryonic development, leading to ...
Brayman, Melissa J +6 more
core +3 more sources
The influence of the cylindrical shape of the nucleosomes and H1 defects on properties of chromatin [PDF]
, 2007 We present a model improving the two-angle model for interphase chromatin (E2A model). This model takes into account the cylindrical shape of the histone octamers, the H1 histones in front of the nucleosomes and the vertical distance $d$ between the in ...
Barbi +31 more
core +3 more sources
Stem Cells International, 2021 Transposable elements (TEs) are mobile genetic sequences capable of duplicating and reintegrating at new regions within the genome. A growing body of evidence has demonstrated that these elements play important roles in host genome evolution, despite ...
Yixuan Low +4 more
doaj +1 more source
Evaluation of genome-wide chromatin library of Stat5 binding sites in human breast cancer [PDF]
, 2005 BACKGROUND: There is considerable interest in identifying target genes and chromatin binding sites for transcription factors in a genome-wide manner. Such information may become useful in diagnosis and treatment of disease, drug target identification ...
LeBaron, Matthew J +2 more
core +3 more sources
LMTK3 represses tumor suppressor-like genes through chromatin remodeling in breast cancer [PDF]
, 2015 LMTK3 is an oncogenic receptor tyrosine kinase (RTK) implicated in various types of cancer, including breast, lung, gastric, and colorectal cancer. It is local-ized in different cellular compartments, but its nuclear function has not been investigated so
Aceto +52 more
core +9 more sources
ATP-dependent chromatosome remodeling [PDF]
, 2008 Chromatin serves to package, protect and organize the complex eukaryotic genomes to assure their stable inheritance over many cell generations. At the same time, chromatin must be dynamic to allow continued use of DNA during a cell's lifetime.
Dimitrov S. +6 more
core +1 more source
Journal of Physics: Condensed Matter, 2003 topical review for the Journal of Physics: Condensed Matter, 90 pages including 24 ...
Everaers, R., Schiessel, H.
openaire +7 more sources
Critical parameters for efficient sonication and improved chromatin immunoprecipitation of high molecular weight proteins [PDF]
, 2016 Solubilization of cross-linked cells followed by chromatin shearing is essential for successful chromatin immunoprecipitation (ChIP). However, this task, typically accomplished by ultrasound treatment, may often become a pitfall of the process, due to ...
Adams, Peter D. +2 more
core +2 more sources
Scientific Reports, 2021 Chromatin configuration influences gene expression in eukaryotes at multiple levels, from individual nucleosomes to chromatin domains several Mb long.
John A. Halsall +6 more
doaj +1 more source