Results 91 to 100 of about 28,191 (215)
The Plant Journal, 2020 Histone chaperones mediate assembly and disassembly of nucleosomes and participate in essentially all DNA-dependent cellular processes. In Arabidopsis thaliana, loss-of-functions of FAS1 or FAS2 subunits of the H3-H4 histone chaperone complex CHROMATIN ...
K. Kolářová +5 more
semanticscholar +1 more source
Cell Proliferation, EarlyView.Active nucleoli have the capability to release perinuclear heterochromatin, which is a novel event of iPSC reprogramming. ABSTRACT Ribosome biogenesis occurs within the nucleolus, with the initial step being the transcription of ribosomal DNA (rDNA). Although rDNA transcription is limited in somatic cells, it is more active in stem cells. Nevertheless,
Yuchen Sun +7 more
wiley +1 more source
Role of MAP kinase and myosin light chain kinase in chromosome-induced development of mouse egg polarity [PDF]
, 2005 During maturation, the mouse oocyte is transformed into a highly polarized egg, characterized by an actin cap and cortical granule-free domain (CGFD) overlying the meiotic spindle that is in close proximity to the cortex.
Deng, Manqi +2 more
core +1 more source
Conformational dynamics of the Hop1 HORMA domain reveal a common mechanism with the spindle checkpoint protein Mad2. [PDF]
, 2017 The HORMA domain is a highly conserved protein-protein interaction module found in eukaryotic signaling proteins including the spindle assembly checkpoint protein Mad2 and the meiotic HORMAD proteins.
Corbett, Kevin D +2 more
core +2 more sources
Advanced Science, Volume 12, Issue 21, June 5, 2025.IR783‐stabilized nanodrugs composed of NIR dye IR783, ROS inducer β‐lapachone, and epigenetic modulator CUDC101 are designed for breast cancer immunotherapy. The nanodrugs can not only promote cancer cell apoptosis through HDAC inhibition‐enhanced oxidation therapy but also reshape the immunosuppressive microenvironment, which provides a novel strategy
Jinzhao Liu +6 more
wiley +1 more source
Potential functions of histone H3.3 lysine 56 acetylation in mammals
Epigenetics, 2022 H3K56 acetylation (H3K56Ac) was first identified in yeast and has recently been reported to play important roles in maintaining genomic stability, chromatin assembly, DNA replication, cell cycle progression and DNA repair.
Lei Fang +5 more
doaj +1 more source
SKIL Promotes Pancreatic Cancer Metastasis by Inhibiting TSPYL2 to Activate the TGF‐β Pathway
Cancer Innovation, Volume 4, Issue 3, June 2025.The elevated expression of the SKIL gene is associated with poor prognosis in pancreatic cancer patients. High SKIL expression activates the TGF‐β pathway by inhibiting the expression of the TSPYL2 gene, subsequently inducing the epithelial–mesenchymal transition (EMT) through the downregulation of E‐cadherin expression and the upregulation of Vimentin
Chenxi Wang +6 more
wiley +1 more source
The COPI Complex Functions in Nuclear Envelope Breakdown and Is Recruited by the Nucleoporin Nup153 [PDF]
, 2003 Nuclear envelope breakdown is a critical step in the cell cycle of higher eukaryotes. Although integral membrane proteins associated with the nuclear membrane have been observed to disperse into the endoplasmic reticulum at mitosis, the mechanisms ...
Fager, Ammon M +3 more
core +1 more source
Molecular Biology of the Cell, 2006 We have studied assembly of chromatin using Xenopus egg extracts and single DNA molecules held at constant tension by using magnetic tweezers. In the absence of ATP, interphase extracts were able to assemble chromatin against DNA tensions of up to 3.5 ...
Jie Yan +7 more
semanticscholar +1 more source
The Roles of Epigenetics in the Interplay Between Beneficial Rhizobacteria and Plants
Modern Agriculture, Volume 3, Issue 1, June 2025.The activity of PGPR in soil enhances the availability of nutrients and hormones secreted by these PGPRs, while nutrients acquired from PGPR‐enriched soil induce epigenetic modifications in plants. These altered epigenetic marks subsequently regulate plant gene expression patterns, including those involved in metabolite synthesis (such as root exudates)
Rui Zou +5 more
wiley +1 more source