Results 111 to 120 of about 31,713 (195)

Regulation of Chromatin Assembly/Disassembly by Rtt109p, a Histone H3 Lys56-specific Acetyltransferase, in Vivo [PDF]

, 2010
Geetha Durairaj, Priyasri Chaurasia, Shweta Lahudkar, Shivani Malik, Abhijit Shukla, Sukesh R. Bhaumik   +5 more
openalex   +1 more source

Molecular Insights Into Heat Stress Resilience in Chickpea Near‐Isogenic Lines

Plant, Cell &Environment, EarlyView.
Miriam Negussu, Maria Ventimiglia, Chiara Vergata, Matteo Buti, David J. Bonfil, Dudy Bar‐Zvi, Michele Zaccai, Federico Martinelli   +7 more
wiley   +1 more source

Histone Chaperone Jun Dimerization Protein 2 (JDP2): Role in Cellular Senescence and Aging

Kaohsiung Journal of Medical Sciences, 2010
Transcription factor Jun dimerization protein 2 (JDP2) binds directly to histones and DNA, and inhibits p300-mediated acetylation of core histones and reconstituted nucleosomes that contain JDP2-recognition DNA sequences.
Yu-Chang Huang, Shigeo Saito, Kazunari Kzaushige Yokoyama   +2 more
doaj   +1 more source

Transcriptomic analysis identifies B-lymphocyte kinase as a therapeutic target for desmoplastic small round cell tumor cancer stem cell-like cells

Oncogenesis
Desmoplastic small round cell tumor (DSRCT) is an aggressive pediatric cancer caused by the EWSR1-WT1 fusion oncoprotein. The tumor is refractory to treatment with a 5-year survival rate of only 15–25%, necessitating the development of novel therapeutics,
Justin W. Magrath, Dane A. Flinchum, Alifiani B. Hartono, Shruthi Sanjitha Sampath, Tina M. O’Grady, Melody Baddoo, Liang Haoyang, Xiaojiang Xu, Erik K. Flemington, Sean B. Lee   +9 more
doaj   +1 more source

SCF E3 Ligase Substrates Switch from CAN-D to Can-ubiquitylate

, 2018
Liu et al. (2018) report a mathematical model predicting how the cellular repertoire of SCF E3 ligases is assembled by “adaptive exchange on demand,” with the limited pool of CUL1 scanning the vast sea of F-box proteins for those with substrates ...
Schulman, B., Scott, D.
core   +1 more source

Male meiotic spindle poles are stabilized by TACC3 and cKAP5/chTOG differently from female meiotic or somatic mitotic spindles in mice

Scientific Reports
Transforming acidic acid coiled-coil protein 3 (TACC3) and cytoskeleton associated protein 5 (cKAP5; or colonic hepatic tumor overexpressed gene, chTOG) are vital for spindle assembly and stabilization initiated through TACC3 Aurora-A kinase interaction.
Calvin Simerly, Emily Robertson, Caleb Harrison, Sydney Ward, Charlize George, Jasmine Deleon, Carrie Hartnett, Gerald Schatten   +7 more
doaj   +1 more source

HP1 reshapes nucleosome core to promote phase separation of heterochromatin [PDF]

, 2019
Heterochromatin affects genome function at many levels. It enables heritable gene repression, maintains chromosome integrity and provides mechanical rigidity to the nucleus1,2.
Burlingame, AL, Dharmarajan, V, Griffin, PR, Gross, JD, Narlikar, GJ, Pascal, BD, Sanulli, S, Tibble, RW, Trnka, MJ   +8 more
core  

Role of the ubiquitin-selective CDC-48/UFD-1/NPL-4 chaperone in DNA replication [PDF]

, 2012
Faithful transmission of genomic information requires tight spatiotemporal regulation of DNA replication factors. Posttranslational modifications, such as ubiquitylation, constitute a fast and effective mechanism to control such complex protein function.
Franz, André
core  

The conformational flexibility of the C-terminus of histone H4 promotes histone octamer and nucleosome stability and yeast viability

Epigenetics & Chromatin, 2012
Background The protein anti-silencing function 1 (Asf1) chaperones histones H3/H4 for assembly into nucleosomes every cell cycle as well as during DNA transcription and repair.
Chavez Myrriah S, Scorgie Jean K, Dennehey Briana K, Noone Seth, Tyler Jessica K, Churchill Mair EA   +5 more
doaj   +1 more source

Histone binding of ASF1 is required for fruiting body development but not for genome stability in the filamentous fungus Sordaria macrospora

mBio
The highly conserved eukaryotic histone chaperone ASF1 is involved in the assembly and disassembly of nucleosomes during transcription, DNA replication, and repair. It was the first chaperone discovered to be involved in all three of these processes. The
Jan Breuer, Tobias Busche, Jörn Kalinowski, Minou Nowrousian   +3 more
doaj   +1 more source