Results 131 to 140 of about 19,014 (210)

The NF‐κB Signalling Pathway: Mechanisms, Consequences and Therapeutic Targets

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT Nuclear Factor‐kappa B (NF‐κB) is a master transcriptional regulator orchestrating critical cellular processes, predominantly immunity and inflammation. However, its aberrant constitutive activation has emerged as a unifying pathogenetic hallmark across diverse malignancies, autoimmune disorders, and chronic inflammatory diseases.
Bherouz Pourdad, Arash Pourdad
wiley   +1 more source

Histone binding of ASF1 is required for fruiting body development but not for genome stability in the filamentous fungus Sordaria macrospora

open access: yesmBio
The highly conserved eukaryotic histone chaperone ASF1 is involved in the assembly and disassembly of nucleosomes during transcription, DNA replication, and repair. It was the first chaperone discovered to be involved in all three of these processes. The
Jan Breuer   +3 more
doaj   +1 more source

CpERF‐WRI1 Manipulates Ethylene Sensing by Regulating the Expression of CpERS1 and Fruit Ripening in Papaya

open access: yesPlant Biotechnology Journal, Volume 24, Issue 6, Page 3550-3569, June 2026.
ABSTRACT Ethylene plays a crucial role in fruit ripening and is perceived by specialised receptor proteins embedded in the endoplasmic reticulum (ER) membrane. As an ethylene antagonist, 1‐methylcyclopropene (1‐MCP) binds to these receptors and delays papaya ripening, but improper use can cause ripening disorders.
Ziling Wu   +7 more
wiley   +1 more source

Interactions between nuclear lamins and their binding partners in EDMD fibroblasts [PDF]

open access: yes, 2003
Lamins are components of the nuclear lamina and are divided In A and B-types, which Interact with proteins of the inner nuclear membrane like emerin.
Alvarez-Reyes, Mauricio
core  

The dynamics of kinetochore assembly/disassembly in C. albicans.

open access: yes, 2012
Cellular levels of an essential KT protein maintain centromere clustering and integrity of a KT formed on the foundation of CENP-A containing centromeric chromatin.
Kaustuv Sanyal (169834)   +1 more
core   +1 more source

Hacking the centromere chromatin code: dissecting the epigenetic regulation of centromere identity [PDF]

open access: yes, 2010
The centromere is a specialized chromatin domain that serves as the assembly site for the mitotic kinetochore structure, thereby playing a fundamental role in facilitating the maintenance of the genetic information.
Bergmann, Jan H.
core  

Chromatin gels are auxetic due to cooperative nucleosome assembly and disassembly dynamics

open access: yesChromatin gels are auxetic due to cooperative nucleosome assembly and disassembly dynamics
We study "chromatin gels", model systems for chromatin, to theoretically predict the conditions, under which such gels show negative Poisson's ratios. A chromatin gel shows phase separation due to an instability arising from the disassembly of nucleosomes by RNA polymerases during transcription.
openaire  

Transcriptional regulation of Synaptonemal complex assembly and disassembly during meiosis

open access: yes
Human female meiosis can take several decades to be concluded, as the oocytes enter meiosis before birth and stay arrested in prophase I in a dormant state until puberty. We aim to better understand the mechanisms responsible for the correct awakening of
Marques, Bruno Filipe Pinheiro
core  

Reshaping cancer cell plasticity by P-body dynamics and protein translation. [PDF]

open access: yesCommun Biol
Senatore E   +4 more
europepmc   +1 more source

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