Results 41 to 50 of about 28,191 (215)
Membraneless organelles: a smart design for metabolic control
FEBS Open Bio, 2021 While most organelles are surrounded by membranes, cells also contain membraneless organelles, which remain separated in the cell by avoiding the mixture of their components with the surroundings.
Irene Díaz‐Moreno +1 more
doaj +1 more source
Plant Biotechnology, 2023 Nitrogen (N) availability is one of the most important factors regulating plant metabolism and growth as it affects global gene expression profiles.
Linnan Jie +9 more
semanticscholar +1 more source
Uncoupling of p97 ATPase activity has a dominant negative effect on protein extraction [PDF]
, 2019 p97 is a highly abundant, homohexameric AAA+ ATPase that performs a variety of essential cellular functions. Characterized as a ubiquitin-selective chaperone, p97 recognizes proteins conjugated to K48-linked polyubiquitin chains and promotes their ...
Long, David T. +3 more
core +1 more source
Regulation of lamin properties and functions: does phosphorylation do it all? [PDF]
Open Biology, 2015 The main functions of lamins are their mechanical and structural roles as major building blocks of the karyoskeleton. They are also involved in chromatin structure regulation, gene expression, intracellular signalling pathway modulation and development ...
Magdalena Machowska +2 more
doaj +1 more source
Open Biology, 2022 Lamin A phosphorylation/de-phosphorylation is an important process during cells division as it allows for nuclear envelope (NE) disassembly at mitotic entry and its re-assembly during mitotic exit.
Florentin Huguet +4 more
doaj +1 more source
A Meiotic Checkpoint Alters Repair Partner Bias to Permit Inter-sister Repair of Persistent DSBs [PDF]
, 2019 Accurate meiotic chromosome segregation critically depends on the formation of inter-homolog crossovers initiated by double-strand breaks (DSBs). Inaccuracies in this process can drive aneuploidy and developmental defects, but how meiotic cells are ...
Aguilera López, Andrés +7 more
core +1 more source
Histone deposition promotes recombination-dependent replication at arrested forks.
PLoS Genetics, 2019 Replication stress poses a serious threat to genome stability. Recombination-Dependent-Replication (RDR) promotes DNA synthesis resumption from arrested forks.
Julien Hardy +9 more
doaj +1 more source
Genome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombination. [PDF]
PLoS Genetics, 2007 To investigate the DNA damage response, we undertook a genome-wide study in Saccharomyces cerevisiae and identified 86 gene deletions that lead to increased levels of spontaneous Rad52 foci in proliferating diploid cells.
David Alvaro +2 more
doaj +1 more source
Dynamic chromatin: concerted nucleosome remodelling and acetylation [PDF]
, 2005 The flexibility of chromatin that enables translation of environmental cues into changes in genome utilisation, relies on a battery of enzymes able to modulate chromatin structure in a highly targeted and regulated manner.
Becker, Peter +2 more
core +1 more source
Chromatin remodeling pathways in smooth muscle cell differentiation, and evidence for an integral role for p300. [PDF]
PLoS ONE, 2010 Phenotypic alteration of vascular smooth muscle cells (SMC) in response to injury or inflammation is an essential component of vascular disease. Evidence suggests that this process is dependent on epigenetic regulatory processes.
Joshua M Spin +2 more
doaj +1 more source