Results 21 to 30 of about 19,014 (210)

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Probing the (H3-H4)(2) histone tetramer structure using pulsed EPR spectroscopy combined with site-directed spin labelling [PDF]

, 2009
The (H3-H4)(2) histone tetramer forms the central core of nucleosomes and, as such, plays a prominent role in assembly, disassembly and positioning of nucleosomes.
Ward, Richard, Owen-Hughes, Tom; id_orcid, Norman, David G., Bowman, Andrew, El-Mkami, Hassane, Bowman, A., Owen-Hughes, Tom   +6 more
core   +1 more source

Quantitative analysis of the transcription control mechanism

Molecular Systems Biology, 2010
Gene transcription requires a sequence of promoter state transitions, including chromatin remodeling, assembly of the transcription machinery, and clearance of the promoter by RNA polymerase.
Changhui Mao, Christopher R Brown, Elena Falkovskaia, Shawfeng Dong, Eva Hrabeta‐Robinson, Lauren Wenger, Hinrich Boeger   +6 more
doaj   +1 more source

Transcription factor complex formation and chromatin fine structure alterations at the murine c-fms (CSF-1 receptor) locus during maturation of myeloid precursor cells [PDF]

, 2002
Expression of the gene for the macrophage colony stimulating factor receptor (CSF-1R), c-fms, has been viewed as a hallmark of the commitment of multipotent precursor cells to macrophages.
Bonifer, Constanze, Pieter J.M. Leenen, Himes, R, Clarke, D, Himes, Roy, Riggs, A. D., Bonifer, Constanze; id_orcid, Tagoh, H., Tagoh, Hiromi, Hume, David, Himes, R., Tagoh, H, Hume, D., Leenen, PJ, Roy Himes, Clarke, D., Bonifer, C, Leenen, Pieter J M, Constanze Bonifer, David Hume, Riggs, AD, Bonifer, C., Leenen, P. J. M., Arthur D. Riggs, Leenen, Pieter, Clarke, Deborah, Hiromi Tagoh, Deborah Clarke, Riggs, Arthur D, Hume, D   +29 more
core   +1 more source

Nucleosome disassembly during human non-homologous end joining followed by concerted HIRA- and CAF-1-dependent reassembly

eLife, 2016
The cell achieves DNA double-strand break (DSB) repair in the context of chromatin structure. However, the mechanisms used to expose DSBs to the repair machinery and to restore the chromatin organization after repair remain elusive.
Xuan Li, Jessica K Tyler
doaj   +1 more source

Expression of chicken lamin B2 in Escherichia coli : characterization of its structure, assembly, and molecular interactions [PDF]

, 1991
Chicken lamin B2, a nuclear member of the intermediate-type filament (IF) protein family, was expressed as a full-length protein in Escherichia coli.
Aebi, U., Peter, M., Lustig, A., E Heitlinger, M Häner, M Peter, Häner, M., Nigg, E. A., U Aebi, Heitlinger, E., A Lustig, E A Nigg   +11 more
core   +1 more source

Repo-Man coordinates chromosomal reorganization with nuclear envelope reassembly during mitotic exit [PDF]

, 2011
This article is available open access under a Creative Commons license (http://creativecommons.org/licenses/by/3.0/). Copyright @ 2011 Elsevier Inc.Repo-Man targets protein phosphatase 1 γ (PP1γ) to chromatin at anaphase onset and regulates chromosome ...
Vagnarelli, Paola, Rappsilber, Juri, Susana Ribeiro, David A. Kelly, Ribeiro, S, Sanchez-Pulido, Luis, Luis Sanchez-Pulido, Ponting, CP, Verheyen, Toon, de Lima Alves, F, Sennels, L, de Lima Alves, Flavia, Ponting, Chris P.; id_orcid, Ponting, Chris P., William C. Earnshaw, Earnshaw, William C., Vagnarelli, P, Sennels, Lau, Kelly, David A., Verheyen, T, Chris P. Ponting, Sanchez-Pulido, L, Ribeiro, Susana, Paola Vagnarelli, Juri Rappsilber, Alves, Flavia de Lima, Kelly, DA, Rappsilber, J, Earnshaw, WC, Lau Sennels, Flavia de Lima Alves, Toon Verheyen   +31 more
core   +1 more source

Histone deposition promotes recombination-dependent replication at arrested forks.

PLoS Genetics, 2019
Replication stress poses a serious threat to genome stability. Recombination-Dependent-Replication (RDR) promotes DNA synthesis resumption from arrested forks.
Julien Hardy, Dingli Dai, Anissia Ait Saada, Ana Teixeira-Silva, Louise Dupoiron, Fatemeh Mojallali, Karine Fréon, Francoise Ochsenbein, Brigitte Hartmann, Sarah Lambert   +9 more
doaj   +1 more source

How the cell cycle impacts chromatin architecture and influences cell fate

Frontiers in Genetics, 2015
Since the earliest observations of cells undergoing mitosis, it has been clear that there is an intimate relationship between the cell cycle and nuclear chromatin architecture.
Yiqin eMa, Kiriaki eKanakousaki, Laura eButtitta   +2 more
doaj   +1 more source

Membraneless organelles: a smart design for metabolic control

FEBS Open Bio, 2021
While most organelles are surrounded by membranes, cells also contain membraneless organelles, which remain separated in the cell by avoiding the mixture of their components with the surroundings.
Irene Díaz‐Moreno, Miguel A. De la Rosa   +1 more
doaj   +1 more source