Heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1) maintains muscle progenitor identity by stabilizing the Ppp1r1b-lncRNA-PRC2 complex. [PDF]
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Embryonic stem cell factors DPPA2/4 amplify active H3K4me3-H2AK119ub chromatin domains in non-small cell lung cancer. [PDF]
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Automated chromatin profiling with spa-ChIP-seq uncovers the impacts of condition variations. [PDF]
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Letter to the Editor: Single-cell and multi-omics integrative modeling identifies mitochondrial gene HSPE1 as a therapeutic target in osteosarcoma. [PDF]
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Native Chromatin Immunoprecipitation (N-ChIP) in Primary Cortical Rat Astrocytes
Chromatin immunoprecipitation (ChIP) in conjunction with qPCR or next generation sequencing (ChIPseq) is used to detect protein-DNA interaction. Typically, DNA bound to a protein of interest is captured with an antibody against this protein, and DNA is ...
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The presence or absence of specific transcription factors, chromatin remodeling machineries, chromatin modification enzymes, post-translational histone modifications and histone variants all play crucial roles in the regulation of pathogenicity genes ...
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