Results 11 to 20 of about 357,335 (290)

Insights into HP1a-Chromatin Interactions [PDF]

open access: yesCells, 2020
Understanding the packaging of DNA into chromatin has become a crucial aspect in the study of gene regulatory mechanisms. Heterochromatin establishment and maintenance dynamics have emerged as some of the main features involved in genome stability ...
Silvia Meyer-Nava   +3 more
doaj   +3 more sources

Epigenetics & chromatin: interactions and processes [PDF]

open access: yesEpigenetics & Chromatin, 2013
On 11 to 13 March 2013, BioMed Central will be hosting its inaugural conference, Epigenetics & Chromatin: Interactions and Processes, at Harvard Medical School, Cambridge, MA, USA.
Henikoff Steven, Grosveld Frank
doaj   +4 more sources

Interactions of Cisplatin and Daunorubicin at the chromatin level [PDF]

open access: yesScientific Reports, 2020
Unexpectedly, the widely used anticancer agents Cisplatin (Cis-Pt) and Daunorubicin (Dauno) exhibited cell type- and concentration-dependent synergy or antagonism in vitro.
Bacsó, Zsolt   +7 more
core   +6 more sources

Cohesin-Mediated Chromatin Interactions and Autoimmunity [PDF]

open access: yesFrontiers in Immunology, 2022
Proper physiological functioning of any cell type requires ordered chromatin organization. In this context, cohesin complex performs important functions preventing premature separation of sister chromatids after DNA replication. In partnership with CCCTC-
Venkataragavan Chandrasekaran   +12 more
doaj   +3 more sources

Tetranucleosome Interactions Drive Chromatin Folding [PDF]

open access: yesACS Central Science, 2021
The multiscale organizational structure of chromatin in eukaryotic cells is instrumental to DNA transcription, replication, and repair. At mesoscopic length scales, nucleosomes pack in a manner that serves to regulate gene expression through condensation and expansion of the genome.
Walter Alvarado   +3 more
doaj   +4 more sources

Untangling chromatin interactions [PDF]

open access: yesJournal of Experimental Botany, 2020
The plant nucleus contains myriad subdomains that define and are defined by the composition of their chromatin. On a whole nucleus scale, this includes regions of active euchromatin and inactive heterochromatin, although the boundaries between these states are blurred.
Parry, Geraint   +3 more
openaire   +3 more sources

Stress Conditions Modulate the Chromatin Interactions Network in Arabidopsis

open access: yesFrontiers in Genetics, 2022
Stresses have been known to cause various responses like cellular physiology, gene regulation, and genome remodeling in the organism to cope and survive.
Vikash Kumar Yadav   +14 more
doaj   +1 more source

Long-Range Chromatin Interactions [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2015
To accommodate genomes in the limited space of the cell nucleus and ensure the correct execution of gene expression programs, genomes are packaged in complex fashion in the three-dimensional cell nucleus. As a consequence of the extensive higher-order organization of chromosomes, distantly located genomic regions on the same or distinct chromosomes ...
Dekker, Job, Misteli, Tom
openaire   +3 more sources

ChIAMM: A Mixture Model for Statistical Analysis of Long-Range Chromatin Interactions From ChIA-PET Experiments

open access: yesFrontiers in Genetics, 2020
Chromatin interaction analysis by paired-end tag sequencing (ChIA-PET) is an important experimental method for detecting specific protein-mediated chromatin loops genome-wide at high resolution. Here, we proposed a new statistical approach with a mixture
Yibeltal Arega   +6 more
doaj   +1 more source

Open chromatin interaction maps reveal functional regulatory elements and chromatin architecture variations during wheat evolution

open access: yesGenome Biology, 2022
Background Bread wheat (Triticum aestivum) is an allohexaploid that is generated by two subsequent allopolyploidization events. The large genome size (16 Gb) and polyploid complexity impede our understanding of how regulatory elements and their ...
Jingya Yuan   +11 more
doaj   +1 more source

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