Results 11 to 20 of about 3,249,481 (296)
Chromatin Organization and Function in Drosophila [PDF]
Cells, 2021 Eukaryotic genomes are packaged into high-order chromatin structures organized in discrete territories inside the cell nucleus, which is surrounded by the nuclear envelope acting as a barrier. This chromatin organization is complex and dynamic and, thus,
Palmira Llorens-Giralt +3 more
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Phase-separation in chromatin organization [PDF]
Journal of Biosciences, 2020 The organization of chromatin into different types of compact versus open states provides a means to fine tune gene regulation. Recent studies have suggested a role for phase-separation in chromatin compaction, raising new possibilities for regulating chromatin compartments.
Narlikar, Geeta J
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Polymer models of chromatin organization [PDF]
Frontiers in Genetics, 2013 The exploration of the spatial organization of chromosomes in the cell nucleus has been greatly enhanced by genome-scale technologies such as Hi-C methods. Polymer models are helping to understand the new emerging complex scenarios and here we review some recent developments.
Mariano eBarbieri +7 more
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Nucleomeric Organization of Chromatin [PDF]
European Journal of Biochemistry, 1982 In the nuclei fixed in situ, as well as in nuclei in low‐ionic‐strength solutions containing magnesium ions, chromatin is represented by globular nucleomeric fibrils 20–25 nm in diameter. Staphylococcal or endogenous nucleases cleave chromatin fibrils to nucleomers and multinucleomers.
G I, Kiryanov +2 more
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Automated FRAP microscopy for high-throughput analysis of protein dynamics in chromatin organization and transcription. [PDF]
FEBS Open BioRoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Yavuz S +6 more
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Chromatin organization and expression [PDF]
Genome Biology, 2008 A report on the 29th Lorne Genome Conference on the Organization and Expression of the Genome, Lorne, Australia, 17-21 February 2008.
Sanij, E, Hannan, RD
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Chromatin assembly and organization [PDF]
Journal of Cell Science, 2001 The poster shows the general steps in chromatin assembly and the diversity of chromatin organization. At each step, variation in the basic constituents of chromatin leads to the establishment of distinct final structures. The left-hand column of text provides examples of such variation; the right-
P, Ridgway, G, Almouzni
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Nuclear cytometry and chromatin organization [PDF]
Cytometry Part A, 2018 AbstractThe nuclear‐targeting chemical probe, for the detection and quantification of DNA within cells, has been a mainstay of cytometry—from the colorimetric Feulgen stain to smart fluorescent agents with tuned functionality. The level of nuclear structure and function at which the probe aims to readout, or indeed at which a DNA‐targeted drug acts, is
Smith, Paul J. +2 more
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Architectural RNA in chromatin organization [PDF]
Biochemical Society Transactions, 2020 RNA plays a well-established architectural role in the formation of membraneless interchromatin nuclear bodies. However, a less well-known role of RNA is in organizing chromatin, whereby specific RNAs have been found to recruit chromatin modifier proteins.
Jitendra Thakur, Steven Henikoff
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3D organization of regulatory elements for transcriptional regulation in Arabidopsis
Genome Biology, 2023 Background Although spatial organization of compartments and topologically associating domains at large scale is relatively well studied, the spatial organization of regulatory elements at fine scale is poorly understood in plants.
Li Deng +14 more
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