Results 61 to 70 of about 547,450 (338)
Science Advances, 2019 Proteasomal-regulated chromatin remodeler mediates cocaine relapse during abstinence. Neuroadaptations in the nucleus accumbens (NAc) underlie cue-induced cocaine craving that intensifies (“incubates”) during abstinence and is believed to contribute to ...
Craig T. Werner +13 more
semanticscholar +1 more source
Expression and purification of an NSD3-GB1 fusion protein as a way to study the structure of complex formation with Brd4 ET. [PDF]
, 2020 The BRD4 protein belongs to the bromodomain and extraterminal domain (BET) family of eukaryotic transcription factors, and is linked to several types of cancer, inflammation, and obesity.
Tuokkola, Jennifer
core
The BAH domain of Rsc2 is a histone H3 binding domain [PDF]
, 2013 Bromo-adjacent homology (BAH) domains are commonly found in chromatin-associated proteins and fall into two classes; Remodels the Structure of Chromatin (RSC)-like or Sir3-like. Although Sir3-like BAH domains bind nucleosomes, the binding partners of RSC-
Adams +61 more
core +1 more source
Nature Communications, 2022 Repeated exposure to social stressors in rodents results in behavioural changes. Here the authors show that behavioural adaptations to stress are associated with nuclear organization changes through SWI/SNF chromatin remodeler in specific neuronal ...
Abdallah Zayed +15 more
doaj +1 more source
eLife, 2022 One-dimensional (1D) target search is a well-characterized phenomenon for many DNA-binding proteins but is poorly understood for chromatin remodelers. Herein, we characterize the 1D scanning properties of SWR1, a conserved yeast chromatin remodeler that ...
Claudia C Carcamo +9 more
doaj +1 more source
Histone demethylase KDM5A regulates the ZMYND8–NuRD chromatin remodeler to promote DNA repair
Journal of Cell Biology, 2017 Upon DNA damage, histone modifications are dynamically reshaped to accommodate DNA damage signaling and repair within chromatin. In this study, we report the identification of the histone demethylase KDM5A as a key regulator of the bromodomain protein ...
Fade Gong +4 more
semanticscholar +1 more source
Remodeling is at the heart of chromatin [PDF]
Epigenetics, 2011 Chromatin modifications are integral elements of chromosome structure and its function and the vasculature depends on tissue-specific genome regulation for its development. A general concept for the de-regulation of chromatin modifications in cardiac and vascular disease is also emerging.
openaire +2 more sources
Cell Reports, 2017 Dietary interventions dramatically affect metabolic disease and lifespan in various aging models. Here, we profiled liver microRNA (miRNA), coding, and long non-coding RNA (lncRNA) expression by high-throughput deep sequencing in mice across multiple ...
Christopher D. Green +5 more
doaj +1 more source
Regulation of the nucleosome repeat length in vivo by the DNA sequence, protein concentrations and long-range interactions. [PDF]
, 2014 The nucleosome repeat length (NRL) is an integral chromatin property important for its biological functions. Recent experiments revealed several conflicting trends of the NRL dependence on the concentrations of histones and other architectural chromatin ...
Beshnova, Daria A +3 more
core +2 more sources
Communications Biology, 2018 The catalytic subunits of SWI/SNF-family and INO80-family chromatin remodelers bind actin and actin-related proteins (Arps) through an N-terminal helicase/SANT-associated (HSA) domain.
B. Turegun +3 more
semanticscholar +1 more source