CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
The investigation of ion-exchange properties of novel zwitterionic and amphoteric stationary phases and their application to the separation of inorganic and organic ions [PDF]
Over recent years development of ion chromatography (IC) has focused on new phase technologies to s~multaneously increase efficlency and vary selectivity.
Nesterenko, Ekaterina
core +2 more sources
Hydrophobicity of various cation-exchange columns for ion chromatography
The retention of organic cations including homologues of n-alkylamines, phenylalkylamines, and ethanolamines was investigated for 20 commercially produced cation-exchange columns with varying matrix, bonding chemistry, functional groups, and ion-exchange
Pavel N. Nesterenko +1 more
doaj +1 more source
Determination of chlorine-containing compounds in disinfectants using ion-exchange chromatography
Objectives. To develop a method for the determination of hypochlorite, chloride, chlorite, chlorate, and perchlorate ions in solution; to determine the limits of detection and quantitation for ClO−, Cl−, ClO2−, ClO3−, and ClO4− ions; to evaluate the ...
E. A. Lapina +3 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The isotope effects of neodymium in Nd-glycolate ligand exchange system were studied by using ion exchange chromatography. The separation coefficients of neodymium isotopes, ε’s, were calculated from the observed isotopic ratios at the front and rear ...
Ibrahim Ismail +5 more
doaj +1 more source
Sample preparation in ion-chromatography
lon-chromatography, a relatively new technique in analytical chemistry, has already shown great promise toward solving complex trace analysis problems, in particular the speciation and quantitation of anions.
Koch, W.F.
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
A simplified ion exchange bead-based KOH electrodialytic generator for capillary ion chromatography
A simple potassium hydroxide electrodialytic generator (EDG) with singe membrane configuration is described. In this setup, one cation exchange resin (CER) bead is used to fabricate the EDG in place of the common membrane sheet. The device is implemented
Liang, Xinmiao +3 more
core +1 more source

