The Drosophila histone variant H2A.V works in concert with HP1 to promote kinetochore-driven microtubule formation [PDF]
, 2015 Unlike other organisms that have evolved distinct H2A variants for different functions, Drosophila melanogaster has just one variant which is capable of filling many roles.
Cenci, Giovanni, Verni', Fiammetta
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Positional changes of pericentromeric heterochromatin and nucleoli in postmitotic Purkinje cells during murine cerebellum development [PDF]
, 2004 Previous studies revealed changes of pericentromeric heterochromatin arrangements in postmitotic Purkinje cells (PCs) during postnatal development in the mouse cerebellum (Manuelidis, 1985; Martou and De Boni, 2000). Here, we performed vibratome sections
Cremer, Thomas +4 more
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Differential expression and sex chromosome association of CHD3/4 and CHD5 during spermatogenesis [PDF]
, 2014 ATP-dependent nucleosome remodelers of the CHD family play important roles in chromatin regulation during development and differentiation. The ubiquitously expressed CHD3 and CHD4 proteins are essential for stem cell function and serve to orchestrate ...
Baarends, W.M. (Willy) +8 more
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G3: Genes, Genomes, Genetics, 2017 Microscopically visible chromatin is partitioned into two major components in Arabidopsis thaliana nuclei. On one hand, chromocenters are conspicuous foci of highly condensed “heterochromatic” domains that contain mostly repeated sequences.
Basten L. Snoek +8 more
doaj +1 more source
RNA from a simple-tandem repeat is required for sperm maturation and male fertility in Drosophila melanogaster. [PDF]
, 2019 Tandemly-repeated DNAs, or satellites, are enriched in heterochromatic regions of eukaryotic genomes and contribute to nuclear structure and function. Some satellites are transcribed, but we lack direct evidence that specific satellite RNAs are required ...
Allshire +44 more
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Intricate structure of the interphase chromocenter revealed by proximity-based biotinylation [PDF]
, 2020 Natalia Y. Kochanova
openalex +2 more sources
eLife, 2018 Structures known as chromocenters, comprising satellite DNA and proteins such as D1 or HMGA1, help to contain DNA inside the nucleus between cell divisions.
Susan A Gerbi
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Nuclear mechanostability emerges from satellite DNA condensation into chromocenters
ABSTRACT As the largest organelle, the nucleus endures significant mechanical stresses over the cellular lifespan, and mechanostability – the ability to resist deformation – is critical for genome integrity and function. Here, we reveal that nuclear mechanostability is an emergent property arising from the coalescence of satellite DNA ...
Brändle FB +14 more
europepmc +2 more sources
Nanolesions induced by heavy ions in human tissues: experimental and theoretical studies [PDF]
, 2012 The biological effects of energetic heavy ions are attracting increasing interest for their applications in cancer therapy and protection against space radiation.
Cathrin Wälzlein +12 more
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High-resolution mapping of h1 linker histone variants in embryonic stem cells. [PDF]
PLoS Genetics, 2013 H1 linker histones facilitate higher-order chromatin folding and are essential for mammalian development. To achieve high-resolution mapping of H1 variants H1d and H1c in embryonic stem cells (ESCs), we have established a knock-in system and shown that ...
Kaixiang Cao +15 more
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