Results 31 to 40 of about 6,135 (207)

Ethanol Alters DNMT1/3a/3b Expression Profile, Promotes Persistent DNA Hypomethylation in Human Brain Endothelial Cells and Impairs Late Cortical Angiogenesis. [PDF]

open access: yesJ Neurochem
Ethanol exposure alters brain endothelial cell function and blood–brain barrier integrity. In human brain microcapillary endothelial cells (HBMEC) and mouse brain endothelial cells (MBEC) from a prenatal alcohol exposure (PAE) model, ethanol increased DNA methyltransferas‐1 (DNMT1) activity and reduced DNA methylation, affecting DNMT3a/3b, methyl‐CpG ...
Siqueira M   +6 more
europepmc   +2 more sources

DNA Environment of Centromeres and Non-Homologous Chromosomes Interactions in Mouse

open access: yesCells, 2021
Although the pericentromeric regions of chromosomes that are enriched in tandemly repeated satellite DNA represent a significant part of eukaryotic genomes, they remain understudied, which is mainly due to interdisciplinary knowledge gaps. Recent studies
Victor Spangenberg   +5 more
doaj   +1 more source

Bivalent individualization during chromosome territory formation in Drosophila spermatocytes by controlled condensin II protein activity and additional force generators.

open access: yesPLoS Genetics, 2021
Reduction of genome ploidy from diploid to haploid necessitates stable pairing of homologous chromosomes into bivalents before the start of the first meiotic division.
Luisa Vernizzi, Christian F Lehner
doaj   +1 more source

Principles and functions of pericentromeric satellite DNA clustering into chromocenters

open access: yesSeminars in Cell & Developmental Biology, 2022
Seminars in Cell & Developmental Biology ...
Brändle, Franziska   +2 more
openaire   +3 more sources

Time-lapse imaging of chromocenter disruption in spermatocytes.

open access: yes, 2021
(A) The fluorescent TALE light proteins RedX and Green2/3 were used for analysis of chromocenter disruption by time-lapse imaging. The karyogram indicates the location of the 359 bp satellite locus (red) and the 1.686 satellite loci (green) that recruit ...
Christian F. Lehner (9449522)   +1 more
core   +1 more source

The modular mechanism of chromocenter formation in Drosophila

open access: yeseLife, 2019
A central principle underlying the ubiquity and abundance of pericentromeric satellite DNA repeats in eukaryotes has remained poorly understood. Previously we proposed that the interchromosomal clustering of satellite DNAs into nuclear structures known ...
Madhav Jagannathan   +2 more
doaj   +1 more source

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