Results 161 to 170 of about 157,687 (296)

Surprisingly frequent chromosomal instability in cultivated peanut. [PDF]

open access: yesPlant J
Lamon S   +3 more
europepmc   +1 more source

Hypoxia Induces a Mitotic Survival Advantage After Radiotherapy in Head and Neck Cancer Cells

open access: yesInternational Journal of Cancer, EarlyView.
Hypoxic tumor environments significantly limit radiotherapy effectiveness against cancer, particularly in head and neck squamous cell carcinoma (HNSCC). Here, the authors tracked hypoxic and post‐hypoxic cells using a hypoxia‐fate mapping system in human papillomavirus (HPV)‐positive and HPV‐negative HNSCC models.
Marilyn Wegge   +3 more
wiley   +1 more source

Lymphocyte Micronucleus Formation Is Driven by Inflammation‐Induced Oxidative DNA Damage in Oesophageal Cancer Development

open access: yesInternational Journal of Cancer, EarlyView.
Chromosomal instability is a hallmark of cancer, but minimally invasive ways to detect systemic DNA damage and cancer risk remain limited. Here, using patient blood samples, the authors investigated lymphocyte micronuclei (MN) frequency as a potential marker of DNA damage across the progression from gastroesophageal reflux disease to Barrett's ...
Kathryn Munn   +13 more
wiley   +1 more source

Bizard: A Community‐Driven Platform for Accelerating and Enhancing Biomedical Data Visualization

open access: yesiMetaMed, EarlyView.
Bizard is an open‐source platform that consolidates customizable biomedical data visualization scripts, providing an intuitive interface, tutorials, and community support to enhance analysis and accelerate progress in precision medicine. https://openbiox.github.io/Bizard/ ABSTRACT Biomedical research increasingly relies on heterogeneous, high ...
Kexin Li   +31 more
wiley   +1 more source

bacNeo: A Computational Toolkit for Identifying Bacteria‐Derived Neoantigens in Human Cancers

open access: yesiMetaMed, EarlyView.
We present bacterial neoantigen (bacNeo), a multi‐omics‐based computational software to classify bacterial components (BACC), type bacteria‐bound HLA alleles (BACH), and prioritize bacterial peptides as neoantigens (BACP). Bacterial neoantigen potential is quantified by score for peptide antigenicity recognition & kinetics (SPARK), enabling ...
Yunzhe Wang   +5 more
wiley   +1 more source

Disrupted autophagy overactivates TBK1 and results in mitotic defects promoting chromosomal instability. [PDF]

open access: yesAutophagy
Paul S   +9 more
europepmc   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

open access: yesiNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu   +5 more
wiley   +1 more source

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