Results 141 to 150 of about 92,482 (260)

Epigenetic mechanisms involved in hepatocellular carcinoma development and progression. [PDF]

open access: yeseGastroenterology
Bueloni B   +4 more
europepmc   +1 more source

ATAC‐seq in Emerging Model Organisms: Challenges and Strategies

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Principle of ATAC‐seq (left), overview of arthropod species with published ATAC‐seq data (middle), summary of experimental design (right). ABSTRACT The Assay for Transposase‐Accessible Chromatin with sequencing (ATAC‐seq) is a versatile and widely utilized method for identifying potential regulatory regions, such as promoters and enhancers, within a ...
Duğçar Ebrar Erdoğan   +13 more
wiley   +1 more source

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

The Role of Chronic Inflammation in Pediatric Cancer. [PDF]

open access: yesCancers (Basel)
Mella C   +3 more
europepmc   +1 more source

LncRNA PVT1 Facilitates Phenotypic Switching of Vascular Smooth Muscle Cells in Intracranial Aneurysms by Recruiting KDM1A to Reduce H3K9me2 Modification

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study explores the differential expression of lncRNA PVT1 in intracranial aneurysms (IAs) and its role in the phenotypic switching of vascular smooth muscle cells (VSMCs). PVT1 and ALOX5 expressions in the serum of IA patients and healthy controls were detected by qRT‐PCR.
Yu‐Fei Cheng   +4 more
wiley   +1 more source

Mapping protein–protein interactions by mass spectrometry

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu   +4 more
wiley   +1 more source

A noncanonical role of roX RNAs in autosomal epigenetic repression. [PDF]

open access: yesNat Commun
Li J   +16 more
europepmc   +1 more source

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