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Chromosome Conformation Capture in Primary Human Cells
20163D organization of the genome, its structural and regulatory function of cell identity, is acquiring prominent features in epigenetics studies; more efforts have been done to develop techniques that allow studying nuclear structure. Chromosome conformation capture (3C) has been set up in 2002 from Dekker and from that moment great investments were made
Alice, Cortesi, Beatrice, Bodega
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The Chromosome Conformation Capture (3C) in Drosophila melanogaster
2020The discovery of the DNA double helix by Watson and Crick in 1953 was the first report showing that the genomic information is not contained in a stretched linear molecule. After that, a huge advance in the knowledge of the structure of the eukaryotic genome in the nuclear space has been made over the last decades, bringing us to the widely accepted ...
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Chromosome Conformation Capture (3C and Higher) with Erythroid Samples
2017Chromosome conformation capture (3C) allows for the determination of the proximity in nuclei of DNA sequences that are linearly distant from one another in the genome. Proximity that is above that expected from random interaction provides evidence for potential long-range functional interactions such as between enhancers and their target genes.
Ivan, Krivega, Ann, Dean
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Technical Review: A Hitchhiker’s Guide to Chromosome Conformation Capture
2017The introduction of chromosome conformation capture (3C) technologies boosted the field of 3D-genome research and significantly enhanced the available toolset to study chromosomal architecture. 3C technologies not only offer increased resolution compared to the previously dominant cytological approaches but also allow the simultaneous study of genome ...
Stefan, Grob, Giacomo, Cavalli
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Chromosome Conformation Capture Followed by Genome-Wide Sequencing (Hi-C) in Drosophila Embryos
Methods in Molecular Biology, 2023Yinxiu Zhan +2 more
exaly
Circular Chromosome Conformation Capture Sequencing (4C-Seq) in Primary Adherent Cells
Methods in Molecular Biology, 2022Judith Marsman +2 more
exaly
Analysis of long-range chromatin interactions using Chromosome Conformation Capture
Methods, 2012Job Dekker, Ye Zhan, Natalia Naumova
exaly