Results 51 to 60 of about 1,560,009 (266)
BioTechniques, 2015 Three-dimensional (3-D) genome organization in the nuclear space affects various genomic functions. Circular chromosome conformation capture (4C-seq) is a powerful technique that allows researchers to measure long-range chromosomal interactions with a ...
Michal Schwartz +7 more
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3PD: Rapid design of optimal primers for chromosome conformation capture assays
BMC Genomics, 2009 Background Higher eukaryotes control the expression of their genes by mechanisms that we are just beginning to understand. A complex layer of control is the dynamic spatial organization of the nucleus.
Dieterich Christoph, Fröhler Sebastian
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Chromosome conformation capture uncovers potential genome-wide interactions between human conserved non-coding sequences. [PDF]
PLoS ONE, 2011 Comparative analyses of various mammalian genomes have identified numerous conserved non-coding (CNC) DNA elements that display striking conservation among species, suggesting that they have maintained specific functions throughout evolution.
Daniel Robyr +10 more
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BMC Research Notes, 2022 Objectives Transcriptional regulatory modules are usually modelled via a network, in which nodes correspond to genes and edges correspond to regulatory associations between them.
Thibault Poinsignon +4 more
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Primer sequences for Chromosome Conformation capture Assay.
, 2012 Primer sequences for Chromosome Conformation capture Assay.
Jae-Seon So (151210) +4 more
core +1 more source
Chromosome Conformation Capture (3C) in Budding Yeast [PDF]
Cold Spring Harbor Protocols, 2015 Chromosome conformation capture (3C) is a method for studying chromosomal organization that takes advantage of formaldehyde cross-linking to measure the spatial association of two pieces of chromatin. The 3C method begins with whole-cell formaldehyde fixation of chromatin.
Belton, Jon-Matthew, Dekker, Job
openaire +3 more sources
Simultaneous Profiling of Chromosome Conformation and Gene Expression in Single Cells
Bio-Protocol, 2023 Rapid development in single-cell chromosome conformation capture technologies has provided valuable insights into the importance of spatial genome architecture for gene regulation.
Yujie Chen +3 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Chromosome Conformation Capture Carbon Copy (5C) in Budding Yeast
, 2015 Chromosome conformation capture carbon copy (5C) is a high-throughput method for detecting ligation products of interest in a chromosome conformation capture (3C) library.
Dekker, Job, Belton, Jon-Matthew
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High-resolution analysis of chromosome conformation in hyperthermophilic archaea
, 2021 Summary: Chromosome conformation capture (3C) techniques are emerging as promising approaches to study genome organization in Archaea, the least understood domain of life in terms of chromosome biology. Here, we describe a 3C technique combined with deep
Naomichi Takemata, Stephen D. Bell
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