Results 31 to 40 of about 20,695 (239)
Chromosome Conformation Capture in Bacteria and Archaea
, 2022 The three-dimensional structure of the chromosome is encoded within its sequence and regulates activities such as replication and transcription. This necessitates the study of the spatial organization of the chromosome in relation to the underlying sequence.
Rashid, F.M.Z., Detmar, L., Dame, R.T.
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Novel insights into chromosomal conformations in cancer
Molecular Cancer, 2017 Exploring gene function is critical for understanding the complexity of life. DNA sequences and the three-dimensional organization of chromatin (chromosomal interactions) are considered enigmatic factors underlying gene function, and interactions between
Ruobing Jia +3 more
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Integrating Multi-omic features exploiting Chromosome Conformation Capture data
Frontiers in Genetics, 2015 The representation, integration and interpretation of omic data is a complex task, in particular considering the huge amount of information that is daily produced in molecular biology laboratories all around the world.
Ivan eMerelli +5 more
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Current Issues in Molecular Biology, 2023 Understanding the three-dimensional (3D) structure of chromatin is invaluable for researching how it functions. One way to gather this information is the chromosome conformation capture (3C) technique and its follow-up technique Hi-C.
David Vadnais, Oluwatosin Oluwadare
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Genome-wide analysis reveals no evidence of trans chromosomal regulation of mammalian immune development. [PDF]
PLoS Genetics, 2018 It has been proposed that interactions between mammalian chromosomes, or transchromosomal interactions (also known as kissing chromosomes), regulate gene expression and cell fate determination.
Timothy M Johanson +8 more
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On the demultiplexing of chromosome capture conformation data [PDF]
FEBS Letters, 2015 How to describe the multiple chromosome structures that underlie interactions among genome loci and how to quantify the occurrence of these structures in a cell population remain important challenges to solve, which can be addressed via a proper demultiplexing of chromosome capture conformation related data.
Ivan Junier +4 more
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eLife, 2014 Genomic analyses of microbial populations in their natural environment remain limited by the difficulty to assemble full genomes of individual species.
Martial Marbouty +5 more
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Epigenetic specifications of host chromosome docking sites for latent Epstein-Barr virus
Nature Communications, 2020 Epstein-Barr virus (EBV) episomes tether to the host chromosome via EBNA1. Here, using circular chromosome conformation capture (4C), Kim et al. identify attachment sites and show that EBV episomes preferentially associate with transcriptionally silenced
Kyoung-Dong Kim +8 more
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Scientific Data, 2022 Measurement(s) genome assemble Technology Type(s) Illumina paired-end sequencing, PacBio single molecule sequencing technique (SMRT) and High-through chromosome conformation capture (Hi-C) technologies Sample Characteristic - Organism Micropterus ...
Kuo He +11 more
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Insights about genome function from spatial organization of the genome
Human Genomics, 2018 Over the last 15 years, development of chromosome conformation capture (3C) and its subsequent high-throughput variants in conjunction with the fast development of sequencing technology has allowed investigators to generate large volumes of data giving ...
Shuvra Shekhar Roy +2 more
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