Chromosome conformation capture resolved near complete genome assembly of broomcorn millet [PDF]
Nature Communications, 2019 Broomcorn millet is one of the oldest crops cultivated by human that has strong abiotic stress tolerance. To facilitate genome assisted breeding of this and related species, the authors report its genome assembly and conduct comparative genome structure ...
Junpeng Shi +15 more
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Low-input Capture-C: A Chromosome Conformation Capture Assay to Analyze Chromatin Architecture in Small Numbers of Cells [PDF]
Bio-Protocol, 2017 Chromosome conformation capture (3C) techniques are crucial to understanding tissue-specific regulation of gene expression, but current methods generally require large numbers of cells.
A. Marieke Oudelaar +3 more
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Tethered Chromosome Conformation Capture Sequencing in Triticeae: A Valuable Tool for Genome Assembly [PDF]
Bio-Protocol, 2018 Chromosome conformation capture sequencing (Hi-C) is a powerful method to comprehensively interrogate the three-dimensional positioning of chromatin in the nucleus.
Axel Himmelbach +3 more
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BioTechniques, 2015 Three-dimensional (3-D) genome organization in the nuclear space affects various genomic functions. Circular chromosome conformation capture (4C-seq) is a powerful technique that allows researchers to measure long-range chromosomal interactions with a ...
Michal Schwartz +7 more
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Sequence-based multiscale modeling for high-throughput chromosome conformation capture (Hi-C) data analysis. [PDF]
PLoS ONE, 2018 In this paper, we introduce sequence-based multiscale modeling for biomolecular data analysis. We employ spectral clustering method in our modeling and reveal the difference between sequence-based global scale clustering and local scale clustering ...
Kelin Xia
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A cautionary note on the use of chromosome conformation capture in plants [PDF]
Plant Methods, 2017 Background The chromosome conformation capture (3C) technique is a method to study chromatin interactions at specific genomic loci. Initially established for yeast the 3C technique has been adapted to plants in recent years in order to study chromatin ...
Suraj Jamge +3 more
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Application of Chromosome Conformation Capture Method for Detection MYC/TRD Chromosomal Translocation in Leukemia Cell Line [PDF]
International Journal of Hematology-Oncology and Stem Cell Research, 2020 Background: Chromosomal breakpoints are the most common cause of hereditary diseases and cancers. Today, many standard clinical methods such as cytogenetic and PCR based techniques are used which have limitation regarding detection resolution. Chromosome
Moloud Absalan +7 more
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A streamlined tethered chromosome conformation capture protocol. [PDF]
BMC Genomics, 2016 Identification of locus-locus contacts at the chromatin level provides a valuable foundation for understanding of nuclear architecture and function and a valuable tool for inferring long-range linkage relationships. As one approach to this, chromatin conformation capture-based techniques allow creation of genome spatial organization maps.
Gabdank I +3 more
europepmc +4 more sources
Chromosome conformation capture uncovers potential genome-wide interactions between human conserved non-coding sequences. [PDF]
PLoS ONE, 2011 Comparative analyses of various mammalian genomes have identified numerous conserved non-coding (CNC) DNA elements that display striking conservation among species, suggesting that they have maintained specific functions throughout evolution.
Daniel Robyr +10 more
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Improved Brassica rapa reference genome by single-molecule sequencing and chromosome conformation capture technologies [PDF]
Horticulture Research, 2018 Genomes: a new map of field mustard A detailed third-generation genome sequence has been published for Brassica rapa, which includes crops such as napa cabbage, turnips, and bok choy.
Lei Zhang +19 more
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