Results 101 to 110 of about 10,432 (143)

SMC ensures efficient chromosome replication and oriC positioning during Streptomyces spore germination. [PDF]

Sci Rep
Pawlikiewicz K, Strzałka A, Nurek A, Donczew M, Gierlikowska A, Gongerowska-Jac M, Szafran MJ, Jakimowicz D.   +7 more
europepmc   +1 more source

A non-coding ABO regulatory variant associated with VWF levels, thrombosis risk, and COVID-19 severity is topologically linked to ADAMTS13 in endothelial cells. [PDF]

HGG Adv
Esposito DV, Sobrinho HFS, Marques MR.
europepmc   +1 more source

Essential roles of CTCF binding sites at TAD boundaries in modulating chromatin interactions and transcriptional regulation at the <i>Ifng</i> locus. [PDF]

Front Immunol
Muto K, Yoshida D, Suzuki T, Yamamoto N, Inoue N, Murakami-Sekimata A, Iseki K, Sekimata M.   +7 more
europepmc   +1 more source

Physics-Based Modeling of Sparse Single-Cell Hi-C Uncovers Structural and Epigenetic Variability. [PDF]

Int J Mol Sci
Vercellone F, Kundu S, Esposito A, Chiariello AM, Conte M, Abraham A, Fontana A, Di Pierno F, Guha S, Di Carluccio C, Olimpo M, Nicodemi M, Casale FP, Bianco S.   +13 more
europepmc   +1 more source

LINE-1 Locus Transcription Nucleates Oncogenic Chromatin Architecture. [PDF]

Cancer Discov
Lee M, Zhang Y, Lim JYS, Dai T, Ye J, Cervantes MB, Sondhi V, Zheng S, Kim YJ, Chen B, DeBerardinis RJ, Xu J.   +11 more
europepmc   +1 more source

Association of hepatitis B virus genomes with active chromatin hubs challenges host replication fidelity, leading to DNA damage. [PDF]

J Virol
Marcoe GJ, Larsen CIS, Summers MF, Majumder K.   +3 more
europepmc   +1 more source

Dynamics and interplay of gene expression and chromosome organization across a predatory lifecycle

van Raaphorst R, Yáñez-Cuna FO, Pascal C, Tran N, Kaljević J, Panigrahi S, Le TBK, Koszul R, Laloux G.   +8 more
europepmc   +1 more source

Subtelomeric Chromatin Structure by Chromosome Conformation Capture (3C)-qPCR Methodology in Candida glabrata

, 2022
Chromatin architecture has an enormous impact on gene regulation, DNA replication, repair, and packaging. Chromatin is organized in a complex hierarchical manner in which distant fragments of DNA can interact with each other through DNA loops. DNA loops can interact between themselves to form topologically associated domains (TADs) that are further ...
Eunice López-Fuentes, Grecia Hernández-Hernández, Alejandro De Las Peñas, Irene Castaño   +3 more
openalex   +3 more sources

The Chromosome Conformation Capture (3C) in Drosophila melanogaster

, 2020
The discovery of the DNA double helix by Watson and Crick in 1953 was the first report showing that the genomic information is not contained in a stretched linear molecule. After that, a huge advance in the knowledge of the structure of the eukaryotic genome in the nuclear space has been made over the last decades, bringing us to the widely accepted ...
Federica Lo Sardo
openalex   +3 more sources