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Chromosome Conformation Capture (3C) of Tandem Arrays in Yeast
, 2014 Studying interphase chromosome arrangements at the molecular level can provide important details on the function and coordination of many metabolic processes that take place on DNA, such as transcription or DNA repair. The chromosome conformation capture (3C) methodology was originally developed in yeast to study the interphase organization of a single-
María D. Mayán, Luís Aragón
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Chromosome Conformation Capture (3C and Higher) with Erythroid Samples
, 2017 Chromosome conformation capture (3C) allows for the determination of the proximity in nuclei of DNA sequences that are linearly distant from one another in the genome. Proximity that is above that expected from random interaction provides evidence for potential long-range functional interactions such as between enhancers and their target genes.
Ivan Krivega, Ann Dean
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Analysis of Interactions Between Genomic Loci Through Chromosome Conformation Capture (3C)
Current Protocols in Cell Biology, 2012 AbstractGenome architecture plays a significant role in the regulation of DNA‐based cellular processes such as transcription and recombination. The successful accomplishment of these processes involves coordinated interaction of DNA elements located at a distance from each other. The ‘Chromosome Conformation Capture’ (3C) assay is a convenient tool for
Belal El Kaderi +2 more
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, 2012 Chromosome conformation capture (3C) is a biochemical assay to reveal higher order chromosomal organizations mediated by physical contact between discrete DNA segments in vivo. Chromosomal organizations are involved in transcriptional regulation of a number of genes in various cell types.
Guang-Hua Peng, Shiming Chen
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Chromosome Conformation Capture (3C) and 3C-based Methods
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2010 Kan Zhai, Zhi-Yin WU, Dianke Yu
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Getting an A with the 3Cs: Chromosome Conformation Capture for Undergraduates
Journal of Visualized Experiments, 2023Chromosome conformation capture (3C) is a powerful tool that has spawned a family of similar techniques (e.g., Hi-C, 4C, and 5C, referred to here as 3C techniques) that provide detailed information of the three-dimensional organization of chromatin. The 3C techniques have been used in a wide range of studies, from monitoring the changes in chromatin ...
Joniec, Acadia +4 more
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Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2009 Xing Wang Deng, Yeqin M Kong
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Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2016 Didier Mazel
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