Results 31 to 40 of about 30,070 (249)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

EVALUATION OF SOME GROWTH CHARACTERS AND ALKALOID PRODUCTIVITY OF DIPLOIDY AND TETRAPLOIDY FORMS OF Datura stramonium AND Datura innoxia PLANTS [PDF]

open access: yesJournal of Soil Sciences and Agricultural Engineering, 2004
Field experiment was conducted to study the diversity in growth parameters and alkaloid production between diploidy and tetra ploidy levels of Datura stramonium and Datura innoxia plants. Increases in plant height.
A. A. Youssef   +2 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Glioblastoma Multiforme with a Peculiar Chromosomal Aberration—Double Minute Chromosomes

open access: yesNeurologia medico-chirurgica, 1987
The chromosomal aberration of double minute chromosomes (DMS) is a peculiar structural anomaly characterized by the occurrence of strongly varying numbers of often very small, paired chromatin bodies, in addition to the ordinary chromosomes. A glioblastoma multiforme with DMS was found in a 73-year-old female patient, who had received neither radiation
ARAKI, Osamu   +3 more
openaire   +3 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Present status of haploidy research in onion (Allium cepa) – A review

open access: yesThe Indian Journal of Agricultural Sciences, 2019
Research on haploid induction and their subsequent utilization in basic and genomic research and breeding is still at its infancy due to paucity of research efforts, difficulties in various critical steps, large genome size and limited publications ...
ANIL KHAR   +4 more
doaj   +1 more source

Morphological, Cytological, and Molecular Comparison between Diploid and Induced Autotetraploids of Callisia fragrans (Lindl.) Woodson

open access: yesAgronomy, 2022
The objective of the current study was to assess the efficiency of oryzalin in inducing polyploids in Callisia fragrans (Lindl.) Woodson by in vitro polyploidization.
Kateřina Beranová   +6 more
doaj   +1 more source

The double game of chromosomal inversions in a neotropical butterfly

open access: yesComptes Rendus. Biologies, 2022
Over a century after the first description of a polymorphism controlled by a supergene, these genetic architectures still puzzle biologists. Supergenes are groups of tightly linked loci facilitating the co-segregation of combinations of alleles underlying alternative, complex adaptive strategies. The suppression of recombination at
Jay, Paul, Joron, Mathieu
openaire   +3 more sources

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