Results 41 to 50 of about 30,958 (250)

Present status of haploidy research in onion (Allium cepa) – A review

The Indian Journal of Agricultural Sciences, 2019
Research on haploid induction and their subsequent utilization in basic and genomic research and breeding is still at its infancy due to paucity of research efforts, difficulties in various critical steps, large genome size and limited publications ...
ANIL KHAR, SABINA ISLAM, PRITAM KALIA, REETA BHATIA, ARUN KUMAR   +4 more
doaj   +1 more source

Morphological, cytogenetic and molecular characterization of new somaclonal variants in four caladium (Caladium × hortulanum) cultivars

Ornamental Plant Research, 2023
The discovery of triploids in caladium has raised strong interest in their use in cultivar development. For triploid production, tetraploids must first be generated from elite breeding material without the introduction of deleterious alleles like has ...
S. Brooks Parrish, Michael E. Kane, Zhanao Deng   +2 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Genes and genetics belong to maize haploid induction

Frontiers in Plant Science
Maize (Zea mays L.) is a globally significant cereal crop with diverse food, feed, and industry uses. The rapid development of homozygous inbred lines via double haploid (DH) technology has revolutionized maize breeding, reducing the time and cost ...
Kanogporn Khammona, Kanogporn Khammona, Abil Dermail, Yu-Ru Chen, Thomas Lübberstedt, Samart Wanchana, Theerayut Toojinda, Siwaret Arikit, Siwaret Arikit, Vinitchan Ruanjaichon   +9 more
doaj   +1 more source

Moldovan line MHI the source for obtaining a large number of haploid plants in maize [PDF]

Selekcija i Semenarstvo, 2004
The hypothesis of the shortening the cycle of selection was tested in maize, by using the MHI line (Moldovan Haploid Inducer) for inducing haploids in five F1 elite single crosses, made for the purposes of further inbreeding and gaining new elite inbred ...
Vančetović Jelena M., Vidaković D., Ignjatović-Micić K., Marković N., Delić J.   +4 more
doaj  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

The Effect of cdk1 Gene Knockout on Heat Shock-Induced Polyploidization in Loach (Misgurnus anguillicaudatus)

Life
(1) Background: Polyploid fish are highly important in increasing fish production, improving fish quality, and breeding new varieties. The loach (Misgurnus anguillicaudatus), as a naturally polyploid fish, serves as an ideal biological model for ...
Hanjun Jiang, Qi Lei, Wenhao Ma, Junru Wang, Jing Gong, Xusheng Guo, Xiaojuan Cao   +6 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Stability in chromosome number and DNA content in synthetic tetraploids of Lolium multiflorum after two generations of selection

Ciência Rural
: Chromosome doubling of Italian ryegrass genotypes ( Lolium multiflorum Lam.) adapted to the brazilian edaphoclimatic conditions is an important strategy used by breeders and aims to obtain more vigorous genotypes with better forage quality and disease ...
Roselaine Cristina Pereira, Natália de Souza Santos, Fernanda de Oliveira Bustamante, Andrea Mittelmann, Vânia Helena Techio   +4 more
doaj   +1 more source