Results 101 to 110 of about 191,348 (320)
p53 Prohibits Propagation of Chromosome Segregation Errors that Produce Structural Aneuploidies
Cell Reports, 2017 Summary: The presence of an abnormal karyotype has been shown to be profoundly detrimental at the cellular and organismal levels but is an overt hallmark of cancer.
Mar Soto +6 more
doaj +1 more source
Genome-wide high-resolution mapping of UV-induced mitotic recombination events in Saccharomyces cerevisiae. [PDF]
, 2013 In the yeast Saccharomyces cerevisiae and most other eukaryotes, mitotic recombination is important for the repair of double-stranded DNA breaks (DSBs). Mitotic recombination between homologous chromosomes can result in loss of heterozygosity (LOH).
Petes, Thomas D, Yin, Yi
core +1 more source
Chromosome Segregation: Centromeres Get Bent [PDF]
Current Biology, 2008 Work over the last several decades has shown that kinetochores play an active part in chromosome segregation, while the chromatin and, more to the point, the DNA have gathered little attention. In two intriguing papers, the Bloom and Khodjakov groups show that intercentromeric chromatin plays a much more active part in chromosome segregation than ...
Dorn, Jonas F., Maddox, Paul S.
openaire +2 more sources
Advanced Science, EarlyView.Single‐nucleus multi‐omics profiling of sinonasal squamous cell carcinoma unveils a hypoxia‐driven angiogenic axis. A specific hypoxic tumor subpopulation orchestrates endothelial tip cell differentiation via epigenetically regulated ADM and VEGFA secretion.
Chaelin You +12 more
wiley +1 more source
Loop-extruders alter bacterial chromosome topology to direct entropic forces for segregation
Nature CommunicationsEntropic forces have been argued to drive bacterial chromosome segregation during replication. In many bacterial species, however, specifically evolved mechanisms, such as loop-extruding SMC complexes and the ParABS origin segregation system, contribute ...
Janni Harju +2 more
doaj +1 more source
The coordination of nuclear envelope assembly and chromosome segregation in metazoans
Nucleus, 2020 The nuclear envelope (NE) is composed of two lipid bilayer membranes that enclose the eukaryotic genome. In interphase, the NE is perforated by thousands of nuclear pore complexes (NPCs), which allow transport in and out of the nucleus. During mitosis in
Shiwei Liu, David Pellman
doaj +1 more source
Restriction Fragment Length Polymorphism Linkage Map for Arabidopsis thaliana [PDF]
, 1988 We have constructed a restriction fragment length polymorphism linkage map for the nuclear genome of the flowering plant Arabidopsis thaliana. The map, containing 90 randomly distributed molecular markers, is physically very dense; >50% of the genome is ...
Bowman, John L. +4 more
core +1 more source
Chromosome Segregation: Pushing Plasmids Apart [PDF]
Current Biology, 2002 The ParM ATPase from Escherichia coli plasmid R1 assembles into F-actin-like filaments which appear to push replicated copies of the plasmid to opposite ends of the cell, ensuring partitioning into daughter cells. Might bacterial chromosomes use a similar mitotic strategy for segregation?
openaire +2 more sources
Advanced Science, EarlyView.In this study maize chloroplastic malate dehydrogenase7 (ZmMDH7), is identified as a Rhizoctonia solani resistance gene in maize. ZmMDH7 is regulated by transcription factor ZmWRKY44 via pathogens challenge to elevate mitochondrial ROS and SA signaling pathway.
Luyang Wei +9 more
wiley +1 more source
Chromosome complement and meiosis in three species of the Neotropical bug genus Antiteuchus (Heteroptera, Pentatomidae, Discocephalinae) [PDF]
, 2006 Orcein staining of spermatocytes was used to study the meiotic behavior of holocentric chromosomes in three member of the genus Antiteuchus (commonly known as stink bugs). We describe and illustrate the karyotype of Antiteuchus mixtus, A. sepulcralis and
de Souza, Maria José, Lanzone, Cecilia
core +2 more sources