Results 101 to 110 of about 1,033,685 (362)
A gene-derived SNP-based high resolution linkage map of carrot including the location of QTL conditioning root and leaf anthocyanin pigmentation [PDF]
, 2014 Purple carrots accumulate large quantities of anthocyanins in their roots and leaves. These flavonoid pigments possess antioxidant activity and are implicated in providing health benefits.
Cavagnaro, Pablo Federico +6 more
core +2 more sources
Advanced Science, EarlyView.YAP undergoes phase separation to activate the AJUBA super‐enhancer, driving aberrant mitosis through spindle checkpoint dysregulation in breast cancer. This study uncovers a mechanistic link between YAP condensates, super‐enhancer activation, and aneuploidy formation.
Rui Zhang +8 more
wiley +1 more source
Cell Reports, 2013 Homologous recombination leads to the formation of DNA joint molecules (JMs) that must be resolved to allow chromosome segregation, but how resolution is temporally coupled with chromosome segregation is unknown.
Joao Matos +2 more
doaj +1 more source
Mitosis-specific acetylation tunes Ran effector binding for chromosome segregation
Journal of Molecular Cell Biology, 2017 Stable transmission of genetic information during cell division requires faithful mitotic spindle assembly and chromosome segregation. The Ran GTPase plays a key role in mitotic spindle assembly.
Xiaolin Bao +19 more
semanticscholar +1 more source
Resolving Chromosome Segregation in Bacteria
Microbial Physiology, 2006 Bacterial chromosomes are evenly distributed between daughter cells, however no equivalent eukaryotic mitotic apparatus has been identified yet. Nevertheless, an advance in our understanding of the dynamics of the bacterial chromosome has been accomplished in recent years by adopting fluorescence microscopy techniques to visualize living bacterial ...
Ronen, Hazan +3 more
openaire +2 more sources
Advanced Science, EarlyView.CCDC41 is essential for meiotic maturation in mouse oocytes through regulating Rab7‐positive endosomes fusion with lysosomes and Rab11a‐positive vesicle fusion with the plasma membrane. Abstract Coiled‐coil domain‐containing protein 41 (CCDC41), a core component of centriolar distal appendages involved in centriole assembly and ciliary vesicle docking,
Ying Tian +12 more
wiley +1 more source
Mitotic antipairing of homologous and sex chromosomes via spatial restriction of two haploid sets. [PDF]
, 2018 Pairing homologous chromosomes is required for recombination. However, in nonmeiotic stages it can lead to detrimental consequences, such as allelic misregulation and genome instability, and is rare in human somatic cells.
Hua, Lisa L, Mikawa, Takashi
core +1 more source
On the origin of trisomy 21 Down syndrome [PDF]
, 2008 Background: Down syndrome, characterized by an extra chromosome 21 is the most common genetic cause for congenital malformations and learning disability.
Hultén, Maj A. +6 more
core +2 more sources
Bacterial Chromosome Organization and Segregation [PDF]
Annual Review of Cell and Developmental Biology, 2015 If fully stretched out, a typical bacterial chromosome would be nearly 1 mm long, approximately 1,000 times the length of a cell. Not only must cells massively compact their genetic material, but they must also organize their DNA in a manner that is compatible with a range of cellular processes, including DNA replication, DNA repair, homologous ...
Badrinarayanan, Anjana +2 more
openaire +4 more sources
Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier
Advanced Science, EarlyView.SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao +11 more
wiley +1 more source