Results 61 to 70 of about 995,917 (290)

The MatP/matS Site-Specific System Organizes the Terminus Region of the E. coli Chromosome into a Macrodomain [PDF]

, 2008
The organization of the Escherichia coli chromosome into insulated macrodomains influences the segregation of sister chromatids and the mobility of chromosomal DNA.
Adachi, Bates, Ben-Yehuda, Blakely, Brezellec, Coskun-Ari, Danilova, Esnault, Espéli, Frédéric Boccard, Guarne, Halpern, Hildebrandt, Hojgaard, Lee, Li, Lin, Marie-Agnès Petit, Marston, Mearini, Meriem El Karoui, Murray, Murtin, Nielsen, Nielsen, Niki, Ohsumi, Olivier Espéli, Reyes-Lamothe, Robin, Romain Mercier, Sophie Schbath, Stéphane Robin, Sunako, Thanbichler, Valens, Viollier, Wang, Wang, Yamaichi   +39 more
core   +3 more sources

Segregation but Not Replication of the Pseudomonas aeruginosa Chromosome Terminates at Dif

mBio, 2018
Coordination between chromosome replication and segregation is essential for equal partitioning of genetic material between daughter cells. In bacteria, this is achieved through the proximity of the origin of replication, oriC, and the chromosome ...
Bijit K. Bhowmik, April L. Clevenger, Hang Zhao, Valentin V. Rybenkov   +3 more
doaj   +1 more source

Actin protects mammalian eggs against chromosome segregation errors

Science, 2017
Actin helps chromosome segregation in eggs Spindle microtubules are well known to orchestrate the segregation of chromosomes during egg development. But the other major cytoskeletal component, actin, has not been thought to play a role in this process ...
B. Mogessie, M. Schuh
semanticscholar   +1 more source

Chromosome arrangement and dynamics in the budding bacterium Hyphomonas neptunium [PDF]

, 2016
Faithful chromosome replication and segregation are essential for every living cell and must be tightly coordinated with other cell cycle events such as cell division.
Jung, Alexandra
core   +1 more source

A Cohesin-Based Partitioning Mechanism Revealed upon Transcriptional Inactivation of Centromere. [PDF]

PLoS Genetics, 2016
Transcriptional inactivation of the budding yeast centromere has been a widely used tool in studies of chromosome segregation and aneuploidy. In haploid cells when an essential chromosome contains a single conditionally inactivated centromere (GAL-CEN ...
Michael Tsabar, Julian Haase, Benjamin Harrison, Chloe E Snider, Brittany Eldridge, Lila Kaminsky, Rebecca M Hine, James E Haber, Kerry Bloom   +8 more
doaj   +1 more source

Structural plasticity of the living kinetochore [PDF]

, 2017
The kinetochore is a large, evolutionarily conserved protein structure that connects chromosomes with microtubules. During chromosome segregation, outer kinetochore components track depolymerizing ends of microtubules to facilitate the separation of ...
Akiyoshi, Al-Bassam, Aravamudhan, Aravamudhan, Asbury, Biggins, Biggins, Boris Rubinstein, Brian D. Slaughter, Chan, Cheeseman, Culotti, Daniel, De Wulf, Desai, Duffy, Field, Foley, Gandhi, Gao, Gardner, Gestaut, Grishchuk, Guimaraes, Hartwell, He, Hedges, Hill, Hornung, Hornung, Jaspersen, Jay R. Unruh, Jeffrey J. Lange, Jennifer L. Gerton, Jin, Jin, Joglekar, Joglekar, Joglekar, Joglekar, Karthik Dhatchinamoorthy, Kim, Kosco, Lampert, Liu, Longtine, Mallavarapu, Malvezzi, Manjunatha Shivaraju, Mayer, McAinsh, McIntosh, McKinney, Meng, Mieck, Miller, Miranda, Ng, Obuse, Pavelka, Pearson, Pfau, Podolski, Powers, Ramey, Sarangapani, Schleiffer, Schmidt, Severin, Shivaraju, Smith, Stephens, Su, Suzuki, Tanaka, Tien, Tytell, Umbreit, Usui, van Breugel, van Hooff, Visintin, Walczak, Wang, Welburn, Westermann, Westermann, Winey, Wisniewski, Wolyniak, Yuen   +90 more
core   +1 more source

Bacterial chromosome segregation.

Acta Biochimica Polonica, 2005
In most bacteria two vital processes of the cell cycle: DNA replication and chromosome segregation overlap temporally. The action of replication machinery in a fixed location in the cell leads to the duplication of oriC regions, their rapid separation to the opposite halves of the cell and the duplicated chromosomes gradually moving to the same ...
Aneta A. Bartosik, Grazyna Jagura-Burdzy
openaire   +3 more sources

Deregulation of Chromosome Segregation and Cancer [PDF]

Annual Review of Cancer Biology, 2020
The mitotic spindle assembly checkpoint (SAC) is an intricate cell signaling system that ensures the high fidelity and timely segregation of chromosomes during cell division. Mistakes in this process can lead to the loss, gain, or rearrangement of the genetic material. Gross chromosomal aberrations are usually lethal but can cause birth and development
Curtis, Natalie L., Filippo Ruda, Gian Filippo, Brennan, Paul, Bolanos-Garcia, Victor M.   +3 more
openaire   +3 more sources

Age-cumulative effect of REC8 reduction on meiotic chromosome segregation errors in mice

Reproductive and Developmental Medicine, 2021
Objective: This study aimed to explore the relationship between cohesin subunit REC8 reduction and meiosis chromosome segregation errors in the ovary. Methods: Rec8+/− mice were generated using CRIPSR/Cas9 gene editing.
Li-Yuan Tian, Ling Zhang, Cheng-Qiu Tao, Xiao-Qi Lin, Feng Zhang, Bin Zhang   +5 more
doaj   +1 more source

Segregation of Polymers in Confined Spaces [PDF]

Phys. Biol. 9 066005 ( 2012), 2009
We investigate the motion of two overlapping polymers with self-avoidance confined in a narrow 2d box. A statistical model is constructed using blob free-energy arguments. We find spontaneous segregation under the condition: $L > R_{//}$, and mixing under $L < R_{//}$, where L is the length of the box, and $R_{//}$ the polymer extension in an infinite ...
arxiv   +1 more source