Results 41 to 50 of about 1,217,029 (160)

Exploring Impact of Rare Variation in Systemic Lupus Erythematosus by a Genome Wide Imputation Approach

Frontiers in Immunology, 2019
The importance of low frequency and rare variation in complex disease genetics is difficult to estimate in patient populations. Genome-wide association studies are therefore, underpowered to detect rare variation.
Manuel Martínez-Bueno, Marta E. Alarcón-Riquelme   +1 more
doaj   +1 more source

Global, regional, and national burden of chronic kidney disease attributable to high fasting plasma glucose from 1990 to 2019: a systematic analysis from the global burden of disease study 2019

Frontiers in Endocrinology
PurposeGiven the rising prevalence of high fasting plasma glucose (HFPG) over the past three decades, it is crucial to assess its global, national, and regional impact on chronic kidney disease (CKD).
Huizhi Wei, Jinhong Ren, Rui Li, Xiaoming Qi, Fan Yang, Qingshan Li, Qingshan Li   +6 more
doaj   +1 more source

SMAC mimetics sensitize HIV-infected cells to oncolytic virus-mediated death

Frontiers in Immunology
Elimination of latently and persistently HIV-infected cells is one of the main barriers to finding a cure for HIV. We have demonstrated that cells latently/persistently infected with HIV impair interferon signaling, which makes them susceptible to ...
Bengisu Molyer, Bengisu Molyer, Yasmeen Ameeriar, Yasmeen Ameeriar, Yasmeen Ameeriar, Jonathan B. Angel, Jonathan B. Angel, Jonathan B. Angel   +7 more
doaj   +1 more source

Extracellular vesicles and their content in the context of polycystic ovarian syndrome and endometriosis: a review

Journal of Ovarian Research
Extracellular vesicles (EVs), particles enriched in bioactive molecules like proteins, nucleic acids, and lipids, are crucial mediators of intercellular communication and play key roles in various physiological and pathological processes.
Cyntia Duval, Brandon A. Wyse, Benjamin K. Tsang, Clifford L. Librach   +3 more
doaj   +1 more source

A semi-automated imaging and analysis pipeline for NET quantification and temporal-profiling of NETosis

Frontiers in Immunology
NETosis is a distinct form of neutrophil cell death involved in innate immunity and characterized by the release of DNA, that when dysregulated contributes to tissue damage and target-organ injury.
Chloé Landry, Chloé Landry, Liyuan Wang, Emma Gerber, Emma Gerber, Chet Elliot Holterman, Chet Elliot Holterman, Dylan Burger, Dylan Burger   +8 more
doaj   +1 more source

Chondroitin sulfate proteoglycan 4 (CSPG4) overexpression as an oncogenic driver and prognostic marker for unfavorable outcomes in hepatocellular carcinoma

World Journal of Surgical Oncology
Background A significant challenge in improving outcomes for hepatocellular carcinoma (HCC) patients is the scarcity of reliable prognostic markers and predictive tools.
Changjie Ren, Feihu Yan, Hao Xiang, Tianyu Hong, Abudurexiti Mierxiati, Ling Zhang, Mingda Wang, Chao Wang   +7 more
doaj   +1 more source

Extracellular acyl-CoA-binding protein as an independent biomarker of COVID-19 disease severity

Frontiers in Immunology
BackgroundFactors leading to severe COVID-19 remain partially known. New biomarkers predicting COVID-19 severity that are also causally involved in disease pathogenesis could improve patient management and contribute to the development of innovative ...
Stephane Isnard, Stephane Isnard, Tsoarello Mabanga, Tsoarello Mabanga, Léna Royston, Léna Royston, Léna Royston, Carolina A. Berini, Carolina A. Berini, Simeng Bu, Simeng Bu, Orthy Aiyana, Orthy Aiyana, Hansen Feng, Hansen Feng, Bertrand Lebouché, Bertrand Lebouché, Bertrand Lebouché, Bertrand Lebouché, Cecilia T. Costiniuk, Cecilia T. Costiniuk, Joseph Cox, Joseph Cox, Guido Kroemer, Guido Kroemer, Guido Kroemer, Madeleine Durand, Jean-Pierre Routy, Jean-Pierre Routy, Jean-Pierre Routy, the Biobanque Québécoise de la COVID-19 (BQC-19)   +30 more
doaj   +1 more source

Circulating plasma gelsolin and MRI-based radiomics as biomarkers of platinum resistance in epithelial ovarian cancer: building a multiparameteric prediction algorithm

Journal of Ovarian Research
Background Resistance to platinum-based chemotherapy in epithelial ovarian cancer (EOC) patients is a barrier to disease management. Currently, there are no biomarkers to predict chemoresistance.
Emma Gerber, Rahul Singh, Cheuk Nam Hwang, Lei Cai, Alice S. T. Wong, Dylan Burger, Karen K. L. Chan, Benjamin K. Tsang, Elaine Y. P. Lee   +8 more
doaj   +1 more source

Chronic urticaria with inflammation [PDF]

European Journal of Internal Medicine, 2021
Hiroshi Hori, Takahiko Fukuchi, Hitoshi Sugawara   +2 more
openaire   +2 more sources

Chronic Inflammation [PDF]

The American Journal of Pathology, 1998
openaire   +3 more sources