Results 81 to 90 of about 2,456,607 (422)

Hyperphosphatemia of chronic kidney disease [PDF]

Kidney International, 2008
Observational studies have determined hyperphosphatemia to be a cardiovascular risk factor in chronic kidney disease. Mechanistic studies have elucidated that hyperphosphatemia is a direct stimulus to vascular calcification, which is one cause of morbid cardiovascular events contributing to the excess mortality of chronic kidney disease.
Suresh Mathew, Ping Qiu, Keith A. Hruska, Raymond D. Pratt, Richard J. Lund   +4 more
openaire   +3 more sources

Immunoregulatory mechanisms of the arachidonic acid pathway in cancer

FEBS Letters, EarlyView.
The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine, Matteo Mucci, Antonio Recchiuti, Domenico Mattoscio   +3 more
wiley   +1 more source

Erratum: Evans M, Grams ME, Sang Y, et al., for the Chronic Kidney Disease Prognosis Consortium. Risk factors for prognosis in patients with severely decreased GFR. Kidney Int Rep. 2018;3:625-637. [PDF]

, 2018
[This corrects the article DOI: 10.1016/j.ekir.2018.01.002.]
Chronic Kidney Disease Prognosis Consortium
core   +1 more source

Chronic kidney disease, female infertility, and medically assisted reproduction: a best practice position statement by the Kidney and Pregnancy Group of the Italian Society of Nephrology [PDF]

, 2023
Fertility is known to be impaired more frequently in patients with chronic kidney disease than in the general population. A significant proportion of chronic kidney disease patients may therefore need Medically Assisted Reproduction.
Attini, Rossella, Cabiddu, Gianfranca, Carosso, Andrea Roberto, Ciabatti, Francesca, Gammaro, Linda, Gernone, Giuseppe, Masturzo, Bianca, Montersino, Benedetta, Moroni, Gabriella, Piccoli, Giorgina Barbara, Revelli, Alberto, Santoro, Domenico, Torreggiani, Massimo   +12 more
core   +1 more source

Treatment of chronic kidney disease [PDF]

Kidney International, 2012
Treatment of chronic kidney disease (CKD) can slow its progression to end-stage renal disease (ESRD). However, the therapies remain limited. Blood pressure control using angiotensin-converting enzyme (ACE) inhibitors or angiotensin II receptor blockers (ARBs) has the greatest weight of evidence.
Thomas H. Hostetter, Jeffrey M. Turner, Michal L. Melamed, Carolyn Bauer, Matthew K. Abramowitz   +4 more
openaire   +3 more sources

Adiponectin in Chronic Kidney Disease [PDF]

International Journal of Molecular Sciences, 2020
Adiponectin is the adipokine associated with insulin sensitization, reducing liver gluconeogenesis, and increasing fatty acid oxidation and glucose uptake. Adiponectin is present in the kidneys, mainly in the arterial endothelium and smooth muscle cells, as well as in the capillary endothelium, and might be considered as a marker of many negative ...
Jarosław Przybyciński, Violetta Dziedziejko, Kamila Puchałowicz, Leszek Domański, Andrzej Pawlik   +4 more
openaire   +3 more sources

Mechanism of insulin resistance in a rat model of kidney disease and the risk of developing type 2 diabetes. [PDF]

, 2017
International audienceChronic kidney disease is associated with homeostatic imbalances such as insulin resistance. However, the underlying mechanisms leading to these imbalances and whether they promote the development of type 2 diabetes is unknown.
Arias, Edward B, Beauchemin, Stéphanie, Cartee, Gregory D, Dion, François, Dumayne, Christopher, Henley, Nathalie, Leblond, François A, Lefrançois, Stéphane, Lesage, Sylvie, Pichette, Vincent   +9 more
core   +9 more sources

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Retrospective analysis of crescent score in clinical prognosis of IgA nephropathy

Open Medicine, 2022
The scoring of crescents (Cs) was recently added to the Oxford classification for IgA nephropathy (IgAN). Because of the short-term use of the C score in clinical practice, its validity and applicability need to be verified. We, retrospectively, analyzed
Chen Ying, Yang Yiya, Liang Yumei, Liu Manting, Xiao Wei, Hu Xiaofang   +5 more
doaj   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source