Results 81 to 90 of about 1,319,691 (347)

Emphysematous pyelonephritis in a diabetic child: a case report and review of the literature

Journal of Medical Case Reports
Introduction Emphysematous pyelonephritis is a life-threatening condition characterized by gas accumulation within the kidney and the surrounding tissues, often resulting in tissue necrosis.
Behnaz Bazargani, Mastaneh Moghtaderi, Hassan Esfandiary, Fatemeh Ghanbarian, Noosha Samieefar   +4 more
doaj   +1 more source

Phenotype standardization for drug-induced kidney disease. [PDF]

, 2015
Drug-induced kidney disease is a frequent cause of renal dysfunction; however, there are no standards to identify and characterize the spectrum of these disorders.
Awdishu, Linda, Cerda, Jorge, Chakaravarthi, Raj, Davenport, Andrew, Goldstein, Stuart L, Holden, Arthur L, Macedo, Etienne, Mehta, Ravindra L, Murray, Patrick T   +8 more
core   +2 more sources

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

FEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata   +7 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Retrospective analysis of crescent score in clinical prognosis of IgA nephropathy

Open Medicine, 2022
The scoring of crescents (Cs) was recently added to the Oxford classification for IgA nephropathy (IgAN). Because of the short-term use of the C score in clinical practice, its validity and applicability need to be verified. We, retrospectively, analyzed
Chen Ying, Yang Yiya, Liang Yumei, Liu Manting, Xiao Wei, Hu Xiaofang   +5 more
doaj   +1 more source

Asuhan Keperawatan Pada Tn. N Dengan Gangguan Sistem Perkemihan: Gagal Ginjal Kronik Di Ruang Anggrek Bugenvil RSUD Pandan Arang Boyolali [PDF]

, 2015
Background: Globally chronic kidney disease caused the death of about 850,000 inhabitants annually, while Indonesia in 2006 reached 100,000 people with chronic kidney disease, and in Boyolali district, especially in RSUD.Pandanarang has reached 8 ...
, Agus Sudaryanto, S.Kep., Ns., M.Kes, MUSTIKA RATRI, ANGGI   +1 more
core  

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

A case report of NPHP1 deletion in Chinese twins with nephronophthisis

BMC Medical Genetics, 2020
Background Nephronophthisis (NPHP) is a rare autosomal recessive inherited disorder with high heterogeneity. The majority of NPHP patients progress to end-stage renal disease (ESRD) within the first three decades of life.
Feng Chen, Limeng Dai, Jun Zhang, Furong Li, Jinbo Cheng, Jinghong Zhao, Bo Zhang   +6 more
doaj   +1 more source

Health outcomes of children born to mothers with chronic kidney disease: a pilot study [PDF]

, 2010
This study aimed to study the health of children born to mothers with chronic kidney disease. Twenty-four children born to mothers with chronic kidney disease were compared with 39 matched control children born to healthy mothers without kidney disease ...
Banerjee, I., Barnes, Jacqueline, Powis, S., Shevlin, M., Soo, A., Sutcliffe, A.   +5 more
core   +3 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source