Results 51 to 60 of about 1,322,182 (207)

Impact of Hepatic Encephalopathy on Clinical Characteristics and Adverse Outcomes in Prospective and Multicenter Cohorts of Patients With Acute-on-Chronic Liver Diseases

Frontiers in Medicine, 2021
Importance: Hepatic encephalopathy is a severe complication, and its contribution to clinical adverse outcomes in patients with acute-on-chronic liver diseases from the East is unclear.Objective: We aimed to investigate the impact of hepatic ...
Liyuan Long, Hai Li, Hai Li, Hai Li, Guohong Deng, Guohong Deng, Xianbo Wang, Xianbo Wang, Sihong Lu, Beiling Li, Zhongji Meng, Zhongji Meng, Yanhang Gao, Yanhang Gao, Zhiping Qian, Zhiping Qian, Feng Liu, Feng Liu, Feng Liu, Xiaobo Lu, Xiaobo Lu, Haotang Ren, Jia Shang, Hai Li, Shaoyang Wang, Yubao Zheng, Yubao Zheng, Huadong Yan, Huadong Yan, Shan Yin, Shan Yin, Wenting Tan, Qun Zhang, Xin Zheng, Xin Zheng, Jinjun Chen, Jinjun Chen, Sen Luo, Jinming Zhao, Wei Yuan, Tao Li, Rongjiong Zheng, Junping Liu, Xiaoxiao Liu, Wenyi Gu, Wenyi Gu, Sumeng Li, Xue Mei, Ruochan Chen, Yan Huang, Yan Huang   +50 more
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Recent advances on the mechanisms regulating cholangiocyte proliferation and the significance of the neuroendocrine regulation of cholangiocyte pathophysiology [PDF]

, 2013
Cholangiocytes are epithelial cells lining the biliary epithelium. Cholangiocytes play several key roles in the modification of ductal bile and are also the target cells in chronic cholestatic liver diseases (i.e., cholangiopathies) such as PSC, PBC ...
Alvaro, Domenico, Carpino, G, Franchitto, Antonio, Gaudio, Eugenio, Mancinelli, Romina, Onori, Paolo, Renzi, Anastasia   +6 more
core   +1 more source

Cost-effectiveness of non-invasive methods for assessment and monitoring of liver fibrosis and cirrhosis in patients with chronic liver disease: systematic review and economic evaluation [PDF]

, 2015
BACKGROUND: Liver biopsy is the reference standard for diagnosing the extent of fibrosis in chronic liver disease; however, it is invasive, with the potential for serious complications.
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Alterations in the Gut Microbiota and Hepatitis-B-Virus Infection in Southern Chinese Patients With Coexisting Non-Alcoholic Fatty Liver Disease and Type-2 Diabetes Mellitus

Frontiers in Medicine, 2021
Background: Hepatitis B virus (HBV) infection has been reported to affect the bacterial characteristics in the host. We aimed to elucidate the compositional and functional characteristics of the microbiota in southern Chinese patients with coexistent HBV
Weijia Han, Weijia Han, Chunyang Huang, Yali Ji, Ling Zhou, Jinjun Chen, Jinjun Chen, Jinjun Chen, Jinlin Hou   +8 more
doaj   +1 more source

Orthotopic liver transplantation in children. Two-year experience with 47 patients [PDF]

, 1984
During a 24-month period (May 1981 to May 1983), 47 pediatric patients (ranging in age from 7 months to 18 years) underwent orthotopic liver transplantation using cyclosporine and prednisone.
Gartner, JC, Iwatsuki, S, Malatack, JJ, Shaw, BW, Starzl, TE, Zitelli, BJ   +5 more
core  

Pathologic analysis of liver transplantation for primary biliary cirrhosis [PDF]

, 1988
A retrospective histopathologic review of all pathologic specimens from 394 adult liver transplant patients was undertaken with clinical correlation to determine if primary biliary cirrhosis has affected the posttrans‐plant course compared to all other ...
Ballardini, Baum, Berg, Bernuau, Demetris, Demetris, Demetris, Demetris, Detre, Epstein, Epstein, Esquivel, Fennell, Fung, Haagsma, Iwatsuki, James, MacSween, McFarlane, McFarlane, Neuberger, Popper, Portmann, Portmann, Portmann, Vento   +25 more
core   +1 more source

PSMD14-mediated deubiquitination of CARM1 facilitates the proliferation and metastasis of hepatocellular carcinoma by inducing the transcriptional activation of FERMT1

Cell Death and Disease
Hepatocellular carcinoma (HCC) is a highly potent malignancy. The enzyme coactivator-associated arginine methyltransferase 1 (CARM1) is highly expressed in different types of cancer.
Jing Lu, Huita Wu, Ping Zhan, Yuyan Lu, Qinliang Fang, Changhong Luo, Fuqiang Wang, Jing Wen, Chengrong Xie, Zhenyu Yin   +9 more
doaj   +1 more source

A comprehensive evaluation of the therapeutic potential of silibinin: a ray of hope in cancer treatment

Frontiers in Pharmacology
Natural compounds hold promise in the search for cancer therapies due to their unique chemical structures and combinations that may effectively combat cancer while minimizing toxicity and side effects compared to conventional treatments.
Pantha Prodip Ray, Mohammad Ashraful Islam, Mohammad Safiqul Islam, Aixia Han, Peiwu Geng, Md. Abdul Aziz, Abdullah Al Mamun   +6 more
doaj   +1 more source

Acute-on-chronic Liver Failure: MELD Score 30-day Mortality Predictability and Etiology in a Pakistani Population [PDF]

, 2020
Background: Cirrhosis is a pathological condition that ultimately leads to liver failure. Acute on chronic liver failure (ACLF) has a high short term mortality rate. Viral hepatitis is the most common cause of liver failure in our local population.
Gilani, N. A. (Naeem), Khalid, T. (Talha), Sarfraz, A. (Azza), Sarfraz, M. (Muzna), Sattar, S. (Saim), Siddiq, J. (Javaria)   +5 more
core  

Matrix metalloproteinases in liver injury, repair and fibrosis. [PDF]

, 2015
The liver is a large highly vascularized organ with a central function in metabolic homeostasis, detoxification, and immunity. Due to its roles, the liver is frequently exposed to various insults which can cause cell death and hepatic dysfunction ...
Baber, John, Coito, Ana J, Duarte, Sergio, Fujii, Takehiro   +3 more
core   +1 more source