Results 71 to 80 of about 1,322,182 (207)

Patient-oriented education and medication management intervention for people with decompensated cirrhosis: study protocol for a randomized controlled trial

Trials, 2017
Background People with decompensated cirrhosis require complex medical care and are often prescribed an intricate and frequently changing medication and lifestyle regimen.
Kelly L. Hayward, Jennifer H. Martin, W. Neil Cottrell, Antara Karmakar, Leigh U. Horsfall, Preya J. Patel, David D. Smith, Katharine M. Irvine, Elizabeth E. Powell, Patricia C. Valery   +9 more
doaj   +1 more source

Thrombocytopenia in chronic liver disease [PDF]

Liver International, 2016
AbstractThrombocytopenia is a common haematological disorder in patients with chronic liver disease. It is multifactorial and severity of liver disease is the most influential factor. As a result of the increased risk of bleeding, thrombocytopenia may impact upon medical procedures, such as surgery or liver biopsy.
openaire   +2 more sources

Improving immunotherapy for the treatment of hepatocellular carcinoma: learning from patients and preclinical models

npj Gut and Liver
Hepatocellular carcinoma (HCC), the third cause of cancer-related deaths worldwide, continues to present significant therapeutic challenges. Despite significant therapeutic advancement in the last decade, the efficacy of systemic treatments for patients ...
Romain Desert, Fabio Gianonne, Antonio Saviano, Yujin Hoshida, Mathias Heikenwälder, Pierre Nahon, Thomas F. Baumert   +6 more
doaj   +1 more source

Liver Transplantation for Alcoholic Liver Disease: A Consideration of Reasons For and Against [PDF]

, 1989
Orthotopic liver transplantation is a clinical procedure that has been accepted widely as the treatment of choice for individuals with advanced chronic liver disease.
Dindzans, VJ, Gavaler, JS, Gordon, RD, Iwatsuki, S, Makowka, L, Starzl, TE, Tarter, RE, Todo, S, Tzakis, A, Van Thiel, DH   +9 more
core   +1 more source

Angiogenesis in chronic liver disease

Annals of Hepatology, 2007
Chronic liver disease is characterized by inflammation and fibrosis. As a consequence angiogenesis leading to new vasculature may have prognostic value in disease progression. Interfering with angiogenesis may be a potential target to avoid progression of liver disease. Hence we planned to evaluate the CD34 and vascular endothelial growth factor (VEGF),
Anjali D. Amarapurkar, Deepak N. Amarapurkar, Vibhav, Nikhil D. Patel   +3 more
openaire   +3 more sources

TRIM55 restricts the progression of hepatocellular carcinoma through ubiquitin-proteasome-mediated degradation of NF90

Cell Death Discovery
Hepatocellular carcinoma (HCC) is a prevalent malignant tumor worldwide. Tripartite motif containing 55 (TRIM55), also known as muscle-specific ring finger 2 (Murf2), belongs to the TRIM protein family and serves as an E3 ligase.
Changhong Luo, Yuyan Lu, Qinliang Fang, Jing Lu, Ping Zhan, Wenqing Xi, Jinzhu Wang, Xijun Chen, Qin Yao, Fuqiang Wang, Zhenyu Yin, Chengrong Xie   +11 more
doaj   +1 more source

Screening for significant chronic liver disease by using three simple ultrasound parameters [PDF]

, 2015
Objectives Chronic liver diseases remain asymptomatic for many years. Consequently, patients are diagnosed belatedly, when cirrhosis is unmasked by lifethreatening complications.
C. Aubé, F. Oberti, G. Lignon, J. Boursier, J. Lebigot, S. Delumeau, S. Michalak   +6 more
core   +3 more sources

Case Report: Long-term disease-free survival in an advanced hepatocellular carcinoma patient: an exceptional response to PD-1 inhibitor therapy

Frontiers in Immunology
IntroductionHepatocellular carcinoma (HCC) is a leading cause of cancer-related death, with most patients diagnosed at advanced stages, often precluding surgical resection.
Qinliang Fang, Qinliang Fang, Shuqi Yu, Yu Xiong, Yu Xiong, Yibin Zhang, Yibin Zhang, Xiaomin Wang, Xiaomin Wang, Jianyin Zhou, Jianyin Zhou, Fuqiang Wang, Fuqiang Wang, Zhenyu Yin, Zhenyu Yin   +14 more
doaj   +1 more source

Animal models of NASH: getting both pathology and metabolic context right [PDF]

, 2015
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of referral to liver clinics, and its progressive form, non-alcoholic steatohepatitis (NASH), can lead to cirrhosis and end-stage liver disease.
Larter, Claire Z., Yeh, Matthew M.
core   +1 more source

The Natural History of Hepatitis C Virus Infection and Disease in the Era of Curative Therapy with Direct-Acting Antivirals

Viruses
The availability of highly effective direct-acting antivirals (DAAs) that cure individuals infected with HCV has changed completely the natural history of HCV infection and chronic hepatitis C.
Maurizia Rossana Brunetto, Ferruccio Bonino   +1 more
doaj   +1 more source