Results 111 to 120 of about 7,324,613 (292)

Heterozygous mutations in factor H aggravate pathological damage in a stable IgA deposition model induced by Lactobacillus casei cell wall extract

Frontiers in Immunology
IntroductionActivation of complement through the alternative pathway (AP) has a key role in the pathogenesis of IgA nephropathy (IgAN). We previously showed, by intraperitoneal injection of Lactobacillus casei cell wall extract (LCWE), C57BL/6 mice ...
Jingyi Li, Jingyi Li, Jingyi Li, Jingyi Li, Jingyi Li, Yaping Dong, Yaping Dong, Yaping Dong, Yaping Dong, Yaping Dong, Feifei Chen, Feifei Chen, Feifei Chen, Feifei Chen, Feifei Chen, Hongyu Yang, Hongyu Yang, Hongyu Yang, Hongyu Yang, Hongyu Yang, Pei Chen, Pei Chen, Pei Chen, Pei Chen, Pei Chen, Hongyu Li, Hongyu Li, Hongyu Li, Hongyu Li, Hongyu Li, Sufang Shi, Sufang Shi, Sufang Shi, Sufang Shi, Sufang Shi, Xujie Zhou, Xujie Zhou, Xujie Zhou, Xujie Zhou, Xujie Zhou, Li Zhu, Li Zhu, Li Zhu, Li Zhu, Li Zhu, Yuemiao Zhang, Yuemiao Zhang, Yuemiao Zhang, Yuemiao Zhang, Yuemiao Zhang, Lijun Liu, Lijun Liu, Lijun Liu, Lijun Liu, Lijun Liu, Xinfang Xie, Feng Yu, Jing Jin, Jicheng Lv, Jicheng Lv, Jicheng Lv, Jicheng Lv, Jicheng Lv, Hong Zhang, Hong Zhang, Hong Zhang, Hong Zhang, Hong Zhang   +67 more
doaj   +1 more source

BRG1 is involved in vascular calcification in chronic renal disease via autophagy of vascular smooth muscle cells. [PDF]

iScience, 2023
Feng Y, Yu M, Wang C, Xia J, Huang L, Tang Y, Xiao Q, Pu L, Wang L, Li G, Li Y.   +10 more
europepmc   +1 more source

Real‐World Safety and Effectiveness of JAK Inhibitors in Systemic Sclerosis: A Propensity‐Matched Study From the EUSTAR Cohort

Arthritis Care &Research, EarlyView.
Objective JAK inhibitors (JAKi) have shown promising effects in early‐phase studies of systemic sclerosis (SSc). We aimed to assess the safety and explore the effectiveness of JAKi compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the European Scleroderma Trials and Research Group (EUSTAR) cohort was ...
Stefano Di Donato, Marie‐Elise Truchetet, Marco Minerba, Oliver Distler, Juan José Alegre Sancho, Yolanda Braun‐Moscovici, Christina Bergmann, Petros Sfikakis, Jeska K. de Vries‐Bouwstra, Murray Baron, Silvia Bellando‐Randone, Lorenzo Dagna, Christopher P. Denton, Madelon C. Vonk, Vanessa Smith, Ivan Castellvi, Gabriela Riemekasten, Andra Balanescu, Masataka Kuwana, Maria De Santis, Kamal Solanki, Anastas Batalov, Vahan Mukuchyan, Marco Matucci‐Cerinic, Yannick Allanore, Francesco Del Galdo, Michael Hughes, EUSTAR Collaborators   +27 more
wiley   +1 more source

RENAL FUNCTION IN CHRONIC RENAL DISEASE

Medicine, 1965
N S, BRICKER, S, KLAHR, H, LUBOWITZ, R E, RIESELBACH   +3 more
openaire   +2 more sources

Association of Elevated Platelets and C‐Reactive Protein With Severe Disease and Poor Survival in Systemic Sclerosis

Arthritis Care &Research, EarlyView.
Objective Elevated C‐reactive protein (CRP) levels in systemic sclerosis (SSc) have been linked with severe disease and worse survival, but the role of platelet levels remains unclear. This study examined whether elevated platelet levels, CRP levels, or both are associated with disease severity, progression, and survival in SSc.
Brian S. Lee, Shufeng Li, Srijana Davuluri, Jennifer Lee, Lorinda Chung   +4 more
wiley   +1 more source

Randomized Controlled Trial of the Effect of an Exercise Rehabilitation Program on Symptom Burden in Maintenance Hemodialysis: A Clinical Research Protocol

Canadian Journal of Kidney Health and Disease
Background: People receiving hemodialysis experience high symptom burden that contributes to low functional status and poor health-related quality of life.
Emilie Ford, Krista Stewart, Eric Garcia, Monica Sharma, Reid Whitlock, Ruth Getachew, Krista Rossum, Todd A. Duhamel, Mauro Verrelli, James Zacharias, Paul Komenda, Navdeep Tangri, Claudio Rigatto, Jennifer M. MacRae, Clara Bohm   +14 more
doaj   +1 more source

Development of a Disease Activity Index for the Assessment of VEXAS Syndrome (VEXAS‐DAI)

Arthritis Care &Research, EarlyView.
Objective Vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic syndrome (VEXAS) syndrome is characterized by a complex spectrum of inflammatory and hematologic manifestations. Clinical research to identify effective therapies is urgently needed but is hindered by the lack of validated outcome measures.
Kevin Byram, Heřman Mann, Danielle Hammond, Onima Chowdhury, Sinisa Savic, Yohei Kirino, Carmelo Gurnari, Maël Heiblig, Thibault Comont, Arsène Mekinian, Mrinal M. Patnaik, Lachelle D. Weeks, Gary Ho, Adam Al‐Hakim, Scott Goldberg, Marcela A. Ferrada, Sophie Georgin‐Lavialle, Peter C. Grayson, Emma M. Groarke, Bhavisha Patel, Megan Sullivan, Sarah A. Buckley, Bryan G. Harder, Raman Garcha, David B. Beck, Matthew J. Koster   +25 more
wiley   +1 more source

Temporal superficial arteritis as differential diagnosis in patients with atherosclerotic changes due to advanced chronic renal disease: case report and review of the literature. [PDF]

Radiol Case Rep, 2022
Hernández M, Rodríguez LC, Bastidas N, Rincón O.   +3 more
europepmc   +1 more source

Caregiver Perspectives on the Burden of Disease and Treatment in Uncontrolled Gout

Arthritis Care &Research, EarlyView.
Objective Uncontrolled gout (UG) refers to persistently elevated serum urate (SU) levels >6 mg/dL and ongoing gout symptoms despite use of urate‐lowering therapy (ULT). The objective of this study was to evaluate the burden associated with informal caregiving for individuals with UG.
Angelo Gaffo, Bhavisha Desai, Abiola Oladapo, Nana Kragh, Rebekah Zincavage, Brad Padilla, Naomi Schlesinger   +6 more
wiley   +1 more source

The Effect of Sodium Glucose Cotransporter 2 Inhibitors From a Human Genetic Perspective

Frontiers in Genetics, 2021
Xing-zi Liu, Xing-zi Liu, Xing-zi Liu, Hong Zhang, Hong Zhang, Hong Zhang   +5 more
doaj   +1 more source