Results 1 to 10 of about 10,514 (223)

Chylomicron metabolism in rats: lipolysis, recirculation of triglyceride-derived fatty acids in plasma FFA, and fate of core lipids as analyzed by compartmental modelling

open access: hybridJournal of Lipid Research, 1996
Chylomicrons labeled in vivo with [14C]oleic acid (primarily in triglycerides (TG), providing a tracer for lipolysis) and [3H]retinol (primarily in ester form, providing a tracer for the corelipids) were injected into rats.
M Hultin, R Savonen, T Olivecrona
doaj   +2 more sources

Consumption of low doses of fat prevents the postprandial rise in chylomicron particle concentration and remnant accumulation in healthy normolipidaemic males

open access: yesJournal of Nutritional Science, 2012
Chylomicron particles are continually synthesised and secreted from the intestine even in the absence of ingested fat. It is possible that following consumption of low doses of fat the basal level of chylomicron secretion and subsequent metabolism are ...
Anthony P. James, John C. Mamo
doaj   +1 more source

ApoB48 as an Efficient Regulator of Intestinal Lipid Transport

open access: yesFrontiers in Physiology, 2020
Fatty meals induce intestinal secretion of chylomicrons (CMs) containing apolipoprotein (Apo) B48. These CMs travel via the lymphatic system before entering the circulation.
Chunmin C. Lo, Karen T. Coschigano
doaj   +1 more source

New insights into the role of dietary triglyceride absorption in obesity and metabolic diseases

open access: yesFrontiers in Pharmacology, 2023
The incidence of obesity and associated metabolic diseases is increasing globally, adversely affecting human health. Dietary fats, especially triglycerides, are an important source of energy for the body, and the intestine absorbs lipids through a series
Xiaojing Li   +6 more
doaj   +1 more source

The Role of Interstitial Matrix and the Lymphatic System in Gastrointestinal Lipid and Lipoprotein Metabolism

open access: yesFrontiers in Physiology, 2020
This review emphasizes the events that take place after the chylomicrons are secreted by the enterocytes through exocytosis. First, we will discuss the journey of how chylomicrons cross the basement membrane to enter the lamina propria.
Anna Zhou, Jie Qu, Min Liu, Patrick Tso
doaj   +1 more source

Evidence that chylomicron remnants and beta-VLDL are transported by the same receptor pathway in J774 murine macrophage-derived cells.

open access: yesJournal of Lipid Research, 1990
To characterize lipoprotein uptake by macrophages, we studied J774 murine macrophage-derived cells. Uptake of 125I-labeled beta-VLDL and 125I-labeled chylomicron remnants was saturable, specific, and of high affinity.
J L Ellsworth, A D Cooper, F B Kraemer
doaj  

Role of hepatic lipase in the uptake and processing of chylomicron remnants in rat liver.

open access: yesJournal of Lipid Research, 1994
The participation of hepatic lipase in the initial uptake and processing of chylomicron remnants was studied in the isolated, perfused rat liver. Hepatic lipase activity was either reduced by preperfusion of livers with heparin or inhibited with specific
S Shafi   +3 more
doaj  

Regulation of the hepatic removal of chylomicron remnants and beta-very low density lipoproteins in the rat.

open access: yesJournal of Lipid Research, 1992
The contribution of the low density lipoprotein (LDL) receptor to the removal of chylomicron remnants was determined in vitro and in vivo by using interventions that up- or down-regulate the LDL receptor but not the LDL receptor-related protein (LRP). In
S Jäckle   +4 more
doaj  

Chylomicrons promote intestinal absorption of lipopolysaccharides

open access: yesJournal of Lipid Research, 2009
Recent data suggest that dietary fat promotes intestinal absorption of lipopolysaccharides (LPS) from the gut microflora, which might contribute to various inflammatory disorders.
Sarbani Ghoshal   +4 more
doaj  

N-3 fatty acids and chylomicron metabolism in the rat

open access: yesJournal of Lipid Research, 1997
Dietary n-3 fatty acids (FAs) reduce postprandial triacylglycerol concentrations in humans by unknown mechanisms. Our goals were to reproduce this phenomenon in the rat, and then to determine the mechanism.
W S Harris   +5 more
doaj  

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