Results 1 to 10 of about 10,514 (223)
Chylomicrons labeled in vivo with [14C]oleic acid (primarily in triglycerides (TG), providing a tracer for lipolysis) and [3H]retinol (primarily in ester form, providing a tracer for the corelipids) were injected into rats.
M Hultin, R Savonen, T Olivecrona
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Chylomicron particles are continually synthesised and secreted from the intestine even in the absence of ingested fat. It is possible that following consumption of low doses of fat the basal level of chylomicron secretion and subsequent metabolism are ...
Anthony P. James, John C. Mamo
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ApoB48 as an Efficient Regulator of Intestinal Lipid Transport
Fatty meals induce intestinal secretion of chylomicrons (CMs) containing apolipoprotein (Apo) B48. These CMs travel via the lymphatic system before entering the circulation.
Chunmin C. Lo, Karen T. Coschigano
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New insights into the role of dietary triglyceride absorption in obesity and metabolic diseases
The incidence of obesity and associated metabolic diseases is increasing globally, adversely affecting human health. Dietary fats, especially triglycerides, are an important source of energy for the body, and the intestine absorbs lipids through a series
Xiaojing Li+6 more
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This review emphasizes the events that take place after the chylomicrons are secreted by the enterocytes through exocytosis. First, we will discuss the journey of how chylomicrons cross the basement membrane to enter the lamina propria.
Anna Zhou, Jie Qu, Min Liu, Patrick Tso
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To characterize lipoprotein uptake by macrophages, we studied J774 murine macrophage-derived cells. Uptake of 125I-labeled beta-VLDL and 125I-labeled chylomicron remnants was saturable, specific, and of high affinity.
J L Ellsworth, A D Cooper, F B Kraemer
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Role of hepatic lipase in the uptake and processing of chylomicron remnants in rat liver.
The participation of hepatic lipase in the initial uptake and processing of chylomicron remnants was studied in the isolated, perfused rat liver. Hepatic lipase activity was either reduced by preperfusion of livers with heparin or inhibited with specific
S Shafi+3 more
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The contribution of the low density lipoprotein (LDL) receptor to the removal of chylomicron remnants was determined in vitro and in vivo by using interventions that up- or down-regulate the LDL receptor but not the LDL receptor-related protein (LRP). In
S Jäckle+4 more
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Chylomicrons promote intestinal absorption of lipopolysaccharides
Recent data suggest that dietary fat promotes intestinal absorption of lipopolysaccharides (LPS) from the gut microflora, which might contribute to various inflammatory disorders.
Sarbani Ghoshal+4 more
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N-3 fatty acids and chylomicron metabolism in the rat
Dietary n-3 fatty acids (FAs) reduce postprandial triacylglycerol concentrations in humans by unknown mechanisms. Our goals were to reproduce this phenomenon in the rat, and then to determine the mechanism.
W S Harris+5 more
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